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aroK shikimate kinase 1 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 2847759, updated on 2-May-2024

Summary

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Gene symbol
aroK
Gene description
shikimate kinase 1
Primary source
ASAP:ABE-0011069
Locus tag
b3390
See related
ECOCYC:EG10081
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3377
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Genomic context

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Sequence:
NC_000913.3 (3518543..3519064, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene cell division protein DamX Neighboring gene 3-dehydroquinate synthase Neighboring gene DNA utilization protein HofQ Neighboring gene DNA utilization protein HofP Neighboring gene DNA utilization protein HofO Neighboring gene DNA utilization protein HofN

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Improving the Production of L-Phenylalanine by Identifying Key Enzymes Through Multi-Enzyme Reaction System in Vitro. Ding D, et al. Sci Rep, 2016 Aug 25. PMID 27558633, Free PMC Article
  2. Identification of a missing link in the evolution of an enzyme into a transcriptional regulator. Durante-Rodríguez G, et al. PLoS One, 2013. PMID 23526945, Free PMC Article
  3. Exploring the effects of carbon sources on the metabolic capacity for shikimic acid production in Escherichia coli using in silico metabolic predictions. Ahn JO, et al. J Microbiol Biotechnol, 2008 Nov. PMID 19047820
  4. Mecillinam resistance in Escherichia coli is conferred by loss of a second activity of the AroK protein. Vinella D, et al. J Bacteriol, 1996 Jul. PMID 8682786, Free PMC Article
  5. The gene (aroK) encoding shikimate kinase I from Escherichia coli. Griffin HG, et al. DNA Seq, 1995. PMID 7612934

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: '98 Escherichia coli SWISS-2DPAGE database update.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables shikimate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables shikimate kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables shikimate kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables shikimate kinase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in aromatic amino acid family biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carboxylic acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in chorismate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chorismate biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within response to antibiotic IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
shikimate kinase 1
YP_026215.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3518543..3519064 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026215.2 shikimate kinase 1 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026215.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A418GLX6, A0A418H450
    Conserved Domains (1) summary
    PRK05057
    Location:1 → 173
    aroK; shikimate kinase AroK
Nucleotide Protein
Heading Accession and Version

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