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gntU low-affinity gluconate transporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 2847760, updated on 11-Apr-2024

Summary

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Gene symbol
gntU
Gene description
low-affinity gluconate transporter
Primary source
ASAP:ABE-0174105
Locus tag
b4476
See related
ECOCYC:EG12631
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
b3435; b3436; ECK3421
Summary
GntU is one of four known transporters for gluconate in Escherichia coli, the others being the homologous GntT, GntP and IdnT transporters. [More information is available at EcoCyc: EG12631].
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Genomic context

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Sequence:
NC_000913.3 (3575721..3577061, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene aspartate-semialdehyde dehydrogenase Neighboring gene MarC family putative inner membrane protein YhgN Neighboring gene D-gluconate kinase, thermostable Neighboring gene DNA-binding transcriptional repressor GntR

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of the Escherichia coli gntT and gntU genes and comparison of the products with their homologues. Yamada M, et al. Biosci Biotechnol Biochem, 1996 Sep. PMID 8987614
  2. Mutations affecting gluconate catabolism in Escherichia coli. Genetic mapping of loci for the low affinity transport and the thermoresistant gluconokinase. de Rekarte UD, et al. J Basic Microbiol, 1994. PMID 7815304
  3. Gene organization and transcriptional regulation of the gntRKU operon involved in gluconate uptake and catabolism of Escherichia coli. Izu H, et al. J Mol Biol, 1997 Apr 11. PMID 9135111
  4. Cloning and molecular genetic characterization of the Escherichia coli gntR, gntK, and gntU genes of GntI, the main system for gluconate metabolism. Tong S, et al. J Bacteriol, 1996 Jun. PMID 8655507, Free PMC Article
  5. The mechanism of maintenance of electroneutrality during the transport of gluconate by E. coli. Robin A, et al. FEBS Lett, 1973 Oct 15. PMID 4585187

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carbohydrate:monoatomic cation symporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables gluconate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables gluconate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-gluconate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carbohydrate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in gluconate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in gluconate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in organic substance transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
low-affinity gluconate transporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3575721..3577061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026221.1 low-affinity gluconate transporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026221.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A485J8E5, A0A8S7TD99
    Conserved Domains (1) summary
    PRK10472
    Location:1 → 445
    PRK10472; low affinity gluconate transporter; Provisional
Nucleotide Protein
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