Orc5 Origin recognition complex subunit 5 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Orc5provided by FlyBase
Official Full Name: Origin recognition complex subunit 5provided by FlyBase
Primary source: FLYBASE:FBgn0015271
Locus tag: Dmel_CG7833
See related: AllianceGenome:FB:FBgn0015271
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BG:DS00941.8; br39; CG7833; D-orc5; Dmel\CG7833; DmOrc5; DmORC5; dORC5; l(2)34Df; l(2)br39; ORC; orc5; ORC5
Summary: Predicted to enable DNA replication origin binding activity. Involved in DNA replication initiation; mitotic chromosome condensation; and mitotic spindle organization. Part of nuclear origin of replication recognition complex. Is expressed in several structures, including egg chamber; embryonic brain; embryonic/larval midgut interstitial cell; embryonic/larval nervous system; and extended germ band embryo. Orthologous to human ORC5 (origin recognition complex subunit 5). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (13829837..13831576)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (13829837..13831576)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables DNA replication origin binding	IBA Inferred from Biological aspect of Ancestor more info
enables ribonucleoprotein complex binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA replication	IEA Inferred from Electronic Annotation more info
involved_in DNA replication	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in DNA replication initiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in DNA replication initiation	IDA Inferred from Direct Assay more info	PubMed
involved_in DNA-templated DNA replication	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in mitotic chromosome condensation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitotic spindle organization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of nuclear origin of replication recognition complex	IBA Inferred from Biological aspect of Ancestor more info
part_of nuclear origin of replication recognition complex	IDA Inferred from Direct Assay more info	PubMed
part_of nuclear origin of replication recognition complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of origin recognition complex	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain