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FZD6 frizzled class receptor 6 [ Gallus gallus (chicken) ]

Gene ID: 378788, updated on 3-Apr-2024

Summary

Symbol
FZD6provided by CGNC
Full Name
frizzled class receptor 6provided by CGNC
Primary source
CGNC:49120
See related
Ensembl:ENSGALG00010010938
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
FZ-6
Orthologs
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Genomic context

Location:
chromosome: 2
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (128958449..128985750)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (129165363..129192641)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene ATPase H+ transporting V1 subunit C1 Neighboring gene brain and acute leukemia, cytoplasmic Neighboring gene collagen triple helix repeat containing 1 Neighboring gene solute carrier family 25 member 32 Neighboring gene DDB1 and CUL4 associated factor 13

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
frizzled-6
Names
frizzled family receptor 6
frizzled homolog 6
involved in Wnt signaling, encoding a Wnt receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271931.4NP_001258860.3  frizzled-6 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000044
    UniProtKB/TrEMBL
    A0A8V0Y788, A0A8V0YFQ3
    Related
    ENSGALP00010014827.1, ENSGALT00010026203.1
    Conserved Domains (2) summary
    cd07450
    Location:21151
    CRD_FZ6; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 6 (Fz6) receptor
    cd15032
    Location:189509
    7tmF_FZD6; class F frizzled subfamily 6, member of 7-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    128958449..128985750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040674479.2XP_040530413.1  frizzled-6 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y788, A0A8V0YFQ3
    Related
    ENSGALP00010014821.1, ENSGALT00010026197.1
    Conserved Domains (2) summary
    cd07450
    Location:21151
    CRD_FZ6; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 6 (Fz6) receptor
    cd15032
    Location:189509
    7tmF_FZD6; class F frizzled subfamily 6, member of 7-transmembrane G protein-coupled receptors
  2. XM_040674489.2XP_040530423.1  frizzled-6 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y2J0, A0A8V0YFN9
    Related
    ENSGALP00010014818.1, ENSGALT00010026194.1
    Conserved Domains (2) summary
    cd15032
    Location:131451
    7tmF_FZD6; class F frizzled subfamily 6, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:193
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    129165363..129192641
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910213.1XP_046766169.1  frizzled-6 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y788
  2. XM_046910214.1XP_046766170.1  frizzled-6 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YFN9