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PF3D7_0627500 protein DJ-1 [ Plasmodium falciparum 3D7 ]

Gene ID: 3885695, updated on 10-Sep-2023

Summary

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Gene symbol
PF3D7_0627500
Gene description
protein DJ-1
Locus tag
PF3D7_0627500
Gene type
protein coding
RNA name
protein DJ-1
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 6
Exon count:
3
Sequence:
Chromosome: 6; NC_004327.3 (1101734..1102852, complement)

Chromosome 6 - NC_004327.3Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase RNF5, putative Neighboring gene mitochondrial import inner membrane translocase subunit TIM22, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene transportin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004327.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved human DJ1-subfamily motif (DJSM) is critical for anti-oxidative and deglycase activities of Plasmodium falciparum DJ1. Nair DN, et al. Mol Biochem Parasitol, 2018 Jun. PMID 29753659
  2. Genetic ablation of plasmoDJ1, a multi-activity enzyme, attenuates parasite virulence and reduces oocyst production. Singhal N, et al. Biochem J, 2014 Jul 15. PMID 25091419
  3. PlasmoSEP: Predicting surface-exposed proteins on the malaria parasite using semisupervised self-training and expert-annotated data. El-Manzalawy Y, et al. Proteomics, 2016 Dec. PMID 27714937, Free PMC Article
  4. Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Hall N, et al. Nature, 2002 Oct 3. PMID 12368867

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables peptidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein deglycase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within protein deglycation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within protein folding IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
protein DJ-1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004327.3 Reference assembly

    Range
    1101734..1102852 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_961165.1 → XP_966258.1  protein DJ-1 [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_966258.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024VAN0, A0A024WAR9, A0A024WTA6, A0A024XAP3, A0A0L1II03, A0A0L7K704, A0A2I0BPL2, C6KTB1, W4IK72, W4ITF2, W7FM98, W7FQT5, W7K1C1
    Conserved Domains (1) summary
    cd03135
    Location:7 → 168
    GATase1_DJ-1; Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1
Nucleotide Protein
Heading Accession and Version

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