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PF3D7_0629500 amino acid transporter AAT1 [ Plasmodium falciparum 3D7 ]

Gene ID: 3885735, updated on 10-Sep-2023

Summary

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Gene symbol
PF3D7_0629500
Gene description
amino acid transporter AAT1
Locus tag
PF3D7_0629500
Gene type
protein coding
RNA name
amino acid transporter AAT1
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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See PF3D7_0629500 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
2
Sequence:
Chromosome: 6; NC_004327.3 (1213948..1216005, complement)

Chromosome 6 - NC_004327.3Genomic Context describing neighboring genes Neighboring gene phospholipase, putative Neighboring gene polyadenylate-binding protein 3, putative Neighboring gene RNA-binding protein, putative Neighboring gene SET domain protein, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004327.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Heterologous Expression of a Novel Drug Transporter from the Malaria Parasite Alters Resistance to Quinoline Antimalarials. Tindall SM, et al. Sci Rep, 2018 Feb 6. PMID 29410428, Free PMC Article
  2. Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics. Cowell AN, et al. Science, 2018 Jan 12. PMID 29326268, Free PMC Article
  3. Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Hall N, et al. Nature, 2002 Oct 3. PMID 12368867

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PF3D7_0629500 is a Plasmodium falciparum amino acid transporter responsible for quinoline antimalarials resistance.
    Title: Heterologous Expression of a Novel Drug Transporter from the Malaria Parasite Alters Resistance to Quinoline Antimalarials.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables xenobiotic transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within response to xenobiotic stimulus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in food vacuole IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
amino acid transporter AAT1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004327.3 Reference assembly

    Range
    1213948..1216005 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_961184.1 → XP_966277.1  amino acid transporter AAT1 [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_966277.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024VAM9, A0A024W9S3, A0A024XCP5, A0A0L1IEF8, A0A0L7K7P6, A0A0L7M7X1, C6KTD0, W4IUL9, W7FIQ3, W7G1X4, W7JFB1, W7KJA3
    Conserved Domains (1) summary
    cl00456
    Location:168 → 606
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
Nucleotide Protein
Heading Accession and Version

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