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ndufb2 NADH:ubiquinone oxidoreductase subunit B2 [ Danio rerio (zebrafish) ]

Gene ID: 393764, updated on 27-Mar-2024

Summary

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Official Symbol
ndufb2provided by ZNC
Official Full Name
NADH:ubiquinone oxidoreductase subunit B2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1762
See related
Ensembl:ENSDARG00000045490 AllianceGenome:ZFIN:ZDB-GENE-040426-1762
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:73329; wu:fb78c03
Summary
Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex I. Orthologous to human NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See ndufb2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (22480148..22482900)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (22759173..22761925)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene origin recognition complex, subunit 5 Neighboring gene LHFPL tetraspan subfamily member 3 Neighboring gene lysine (K)-specific methyltransferase 2E Neighboring gene lysine (K)-specific demethylase 7Aa Neighboring gene sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Spatio-temporal regulation of Wnt and retinoic acid signaling by tbx16/spadetail during zebrafish mesoderm differentiation. Mueller RL, et al. BMC Genomics, 2010 Sep 9. PMID 20828405, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC73329

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex I assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial respiratory chain complex I IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in respirasome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
Names
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
NP_001161298.1
NP_957085.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167826.1 → NP_001161298.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial

    See identical proteins and their annotated locations for NP_001161298.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BX537168, CB357970
    UniProtKB/TrEMBL
    A0A8M1PBS8, Q6PBN0
    Related
    ENSDARP00000066903.3, ENSDART00000066904.4
    Conserved Domains (1) summary
    pfam14813
    Location:29 → 96
    NADH_B2; NADH dehydrogenase 1 beta subcomplex subunit 2

  2. NM_200791.2 → NP_957085.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial

    See identical proteins and their annotated locations for NP_957085.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC059649, BX537168
    UniProtKB/TrEMBL
    A0A8M1PBS8, Q6PBN0
    Related
    ENSDARP00000115006.1, ENSDART00000146272.3
    Conserved Domains (1) summary
    pfam14813
    Location:29 → 96
    NADH_B2; NADH dehydrogenase 1 beta subcomplex subunit 2

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    22480148..22482900
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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