RARB retinoic acid receptor beta [Gallus gallus (chicken)] - Gene

Summary

Symbol: RARBprovided by CGNC
Full Name: retinoic acid receptor betaprovided by CGNC
Primary source: CGNC:8589
See related: Ensembl:ENSGALG00010002438
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: NR1B2; RARBETA
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	2	NC_052533.1 (37422055..37746383)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	2	NC_052574.1 (37472707..37797392)

Chromosome 2 - NC_052533.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Study showed that RARB expression was vital for the timely execution of programmed cell death and was furthermore seen to have an influence on the differentiation state of the ciliary ganglion neurons
Title: RARβ regulates neuronal cell death and differentiation in the avian ciliary ganglion.

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General gene information

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Markers

MCW0362 (e-PCR), detects polymorphism
- UniSTS:280201

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables nuclear glucocorticoid receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables nuclear receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to corticotropin-releasing hormone stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in retinoic acid receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
part_of transcription regulator complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: retinoic acid receptor beta

Names: RAR-beta; nuclear receptor subfamily 1 group B member 2; retinoic acid receptor beta 2; retinoic acid receptor beta4'; retinoic acid receptor beta4M; retinoic acid receptor beta4M'

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205326.2 → NP_990657.1 retinoic acid receptor beta

See identical proteins and their annotated locations for NP_990657.1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000037

UniProtKB/Swiss-Prot

P22448, P27537, Q90598, Q91354

UniProtKB/TrEMBL

A0A8V0XGL7

Related

ENSGALP00010003472.1, ENSGALT00010005633.1

Conserved Domains (2) summary

cd06937
Location:186 → 416

NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily

cd06964
Location:82 → 166

NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

37422055..37746383

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040676713.2 → XP_040532647.1 retinoic acid receptor beta isoform X1

UniProtKB/Swiss-Prot

P22448, P27537, Q90598, Q91354

UniProtKB/TrEMBL

A0A8V0XGL7

Conserved Domains (2) summary

cd06937
Location:186 → 416

NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily

cd06964
Location:82 → 166

NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
XM_040676707.2 → XP_040532641.1 retinoic acid receptor beta isoform X1

UniProtKB/Swiss-Prot

P22448, P27537, Q90598, Q91354

UniProtKB/TrEMBL

A0A8V0XGL7

Conserved Domains (2) summary

cd06937
Location:186 → 416

NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily

cd06964
Location:82 → 166

NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
XM_040676732.2 → XP_040532666.1 retinoic acid receptor beta isoform X2

UniProtKB/TrEMBL

A0A8V0XGL7

Conserved Domains (2) summary

cd06937
Location:185 → 415

NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily

cd06964
Location:81 → 165

NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
XM_015281315.4 → XP_015136801.1 retinoic acid receptor beta isoform X2

UniProtKB/TrEMBL

A0A8V0XGL7

Related

ENSGALP00010003480.1, ENSGALT00010005638.1

Conserved Domains (2) summary

cd06937
Location:185 → 415

NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily

cd06964
Location:81 → 165

NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
XM_015281314.4 → XP_015136800.1 retinoic acid receptor beta isoform X1

UniProtKB/Swiss-Prot

P22448, P27537, Q90598, Q91354

UniProtKB/TrEMBL

A0A8V0XGL7

Related

ENSGALP00010003483.1, ENSGALT00010005644.1

Conserved Domains (2) summary

cd06937
Location:186 → 416

NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily

cd06964
Location:82 → 166

NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
XM_046919124.1 → XP_046775080.1 retinoic acid receptor beta isoform X6

UniProtKB/TrEMBL

A0A8V0XFP9

Related

ENSGALP00010003469.1, ENSGALT00010005631.1
XM_015281316.4 → XP_015136802.1 retinoic acid receptor beta isoform X3

UniProtKB/TrEMBL

A0A8V0X5W1

Related

ENSGALP00010003463.1, ENSGALT00010005624.1

Conserved Domains (2) summary

cd06937
Location:179 → 409

NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily

cd06964
Location:75 → 159

NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
XM_015281317.4 → XP_015136803.1 retinoic acid receptor beta isoform X4

UniProtKB/TrEMBL

A0A8V0XGJ5

Conserved Domains (2) summary

cd06937
Location:178 → 408

NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily

cd06964
Location:74 → 158

NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
XM_025147067.3 → XP_025002835.1 retinoic acid receptor beta isoform X5

UniProtKB/TrEMBL

A0A1N8XGG5, A0A8V0X5W1

Related

ENSGALP00010003459.1, ENSGALT00010005620.1

Conserved Domains (2) summary

cd06937
Location:165 → 395

NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily

cd06964
Location:61 → 145

NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
XM_040676766.2 → XP_040532700.1 retinoic acid receptor beta isoform X7

Conserved Domains (2) summary

cd06937
Location:67 → 297

NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily

cl02596
Location:1 → 47

NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

37472707..37797392

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046910456.1 → XP_046766412.1 retinoic acid receptor beta isoform X1

UniProtKB/Swiss-Prot

P22448, P27537, Q90598, Q91354
XM_046910459.1 → XP_046766415.1 retinoic acid receptor beta isoform X1

UniProtKB/Swiss-Prot

P22448, P27537, Q90598, Q91354
XM_046910457.1 → XP_046766413.1 retinoic acid receptor beta isoform X1

UniProtKB/Swiss-Prot

P22448, P27537, Q90598, Q91354
XM_046910461.1 → XP_046766417.1 retinoic acid receptor beta isoform X2
XM_046910460.1 → XP_046766416.1 retinoic acid receptor beta isoform X2
XM_046910458.1 → XP_046766414.1 retinoic acid receptor beta isoform X1

UniProtKB/Swiss-Prot

P22448, P27537, Q90598, Q91354
XM_046910465.1 → XP_046766421.1 retinoic acid receptor beta isoform X6

UniProtKB/TrEMBL

A0A8V0XFP9
XM_046910462.1 → XP_046766418.1 retinoic acid receptor beta isoform X3
XM_046910463.1 → XP_046766419.1 retinoic acid receptor beta isoform X4
XM_046910464.1 → XP_046766420.1 retinoic acid receptor beta isoform X5

UniProtKB/TrEMBL

A0A1N8XGG5
XM_046910466.1 → XP_046766422.1 retinoic acid receptor beta isoform X7