These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_001306080.2 → NP_001293009.1  LIM domain only protein 7 isoform 3

   Status: REVIEWED

   Description

   Transcript Variant: This variant (3) is alternatively spliced at the 5' end, and contains two additional internal coding exons, compared to transcript variant 1. The encoded isoform (3) has a distinct N-terminus and is longer than isoform 1.

   Source sequence(s)

   AF144237, AF330045, AL137782, DA313248, FJ711162

   Consensus CDS

   CCDS81773.1

   UniProtKB/TrEMBL

   F8J2B5, F8WD26

   Related

   ENSP00000366757.4, ENST00000377534.8

   Conserved Domains (6) summary

   cd00014
   Location:17 → 129

   CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

   cd00136
   Location:1003 → 1070

   PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

   cd08368
   Location:1562 → 1620

   LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

   pfam15949
   Location:588 → 734

   DUF4757; Domain of unknown function (DUF4757)

   cd16269
   Location:1218 → 1229

   GBP_C; coiled coil [structural motif]

   cl20817
   Location:1175 → 1231

   GBP_C; Guanylate-binding protein, C-terminal domain

2. NM_001330583.1 → NP_001317512.1  LIM domain only protein 7 isoform 4

   Status: REVIEWED

   Description

   Transcript Variant: This variant (4) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in an isoform (4) with a shorter N-terminus, compared to isoform 1.

   Source sequence(s)

   AA777749, AF144237, AF330045, AL137782, DA438537, FJ711162

   Consensus CDS

   CCDS81774.1

   UniProtKB/TrEMBL

   A0A8V8TKQ1, E9PMT2

   Related

   ENSP00000317802.8, ENST00000321797.12

   Conserved Domains (5) summary

   cd00136
   Location:770 → 837

   PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

   cd08368
   Location:1329 → 1387

   LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

   pfam15949
   Location:355 → 501

   DUF4757; Domain of unknown function (DUF4757)

   cd16269
   Location:985 → 996

   GBP_C; coiled coil [structural motif]

   cl20817
   Location:942 → 998

   GBP_C; Guanylate-binding protein, C-terminal domain

3. NM_001366632.2 → NP_001353561.1  LIM domain only protein 7 isoform 2

   Status: REVIEWED

   Source sequence(s)

   AL137121, AL137782, AL359392

   Consensus CDS

   CCDS53876.1

   UniProtKB/TrEMBL

   A0A0A0MTE2, A0A8V8TKQ1

   Related

   ENSP00000513106.1, ENST00000605961.2

   Conserved Domains (5) summary

   cd00136
   Location:770 → 837

   PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

   cd16269
   Location:985 → 996

   GBP_C; coiled coil [structural motif]

   pfam15949
   Location:355 → 502

   DUF4757; Domain of unknown function (DUF4757)

   cl20817
   Location:942 → 998

   GBP_C; Guanylate-binding protein, C-terminal domain

   cl26511
   Location:943 → 1101

   Neuromodulin_N; Gap junction protein N-terminal region

4. NM_001366633.2 → NP_001353562.1  LIM domain only protein 7 isoform 5

   Status: REVIEWED

   Source sequence(s)

   AL137121, AL137782, AL359392

   UniProtKB/TrEMBL

   F8J2B5

   Conserved Domains (5) summary

   cd00136
   Location:961 → 1028

   PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

   cd16269
   Location:1176 → 1187

   GBP_C; coiled coil [structural motif]

   pfam15949
   Location:546 → 693

   DUF4757; Domain of unknown function (DUF4757)

   cl20817
   Location:1133 → 1189

   GBP_C; Guanylate-binding protein, C-terminal domain

   cl26511
   Location:1134 → 1292

   Neuromodulin_N; Gap junction protein N-terminal region

5. NM_001366634.2 → NP_001353563.1  LIM domain only protein 7 isoform 6

   Status: REVIEWED

   Source sequence(s)

   AL137121, AL137782, AL359392

   UniProtKB/TrEMBL

   A0A8V8TKQ1

   Conserved Domains (6) summary

   cd00136
   Location:676 → 743

   PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

   cd08368
   Location:1235 → 1293

   LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

   cd16269
   Location:891 → 902

   GBP_C; coiled coil [structural motif]

   pfam15949
   Location:261 → 408

   DUF4757; Domain of unknown function (DUF4757)

   cl20817
   Location:848 → 904

   GBP_C; Guanylate-binding protein, C-terminal domain

   cl26511
   Location:849 → 1007

   Neuromodulin_N; Gap junction protein N-terminal region

6. NM_001366636.2 → NP_001353565.1  LIM domain only protein 7 isoform 6

   Status: REVIEWED

   Source sequence(s)

   AL137121, AL137782, AL359392

   UniProtKB/TrEMBL

   A0A8V8TKQ1

   Conserved Domains (6) summary

   cd00136
   Location:676 → 743

   PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

   cd08368
   Location:1235 → 1293

   LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

   cd16269
   Location:891 → 902

   GBP_C; coiled coil [structural motif]

   pfam15949
   Location:261 → 408

   DUF4757; Domain of unknown function (DUF4757)

   cl20817
   Location:848 → 904

   GBP_C; Guanylate-binding protein, C-terminal domain

   cl26511
   Location:849 → 1007

   Neuromodulin_N; Gap junction protein N-terminal region

7. NM_005358.5 → NP_005349.3  LIM domain only protein 7 isoform 1

   See identical proteins and their annotated locations for NP_005349.3

   Status: REVIEWED

   Description

   Transcript Variant: This variant (1) encodes isoform 1.

   Source sequence(s)

   AA777749, AB020665, AF330045, AL137244, AW805522, DB064574

   Consensus CDS

   CCDS9454.1

   UniProtKB/TrEMBL

   A0A1P7ZIM8

   Related

   ENSP00000342112.4, ENST00000341547.8

   Conserved Domains (6) summary

   cd00014
   Location:74 → 181

   CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

   cd00136
   Location:721 → 788

   PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

   cd08368
   Location:1280 → 1338

   LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

   pfam15949
   Location:294 → 452

   DUF4757; Domain of unknown function (DUF4757)

   cd16269
   Location:936 → 947

   GBP_C; coiled coil [structural motif]

   cl20817
   Location:893 → 949

   GBP_C; Guanylate-binding protein, C-terminal domain

8. NM_015842.2 → NP_056667.2  LIM domain only protein 7 isoform 2

   See identical proteins and their annotated locations for NP_056667.2

   Status: REVIEWED

   Description

   Transcript Variant: This variant (2) is alternatively spliced at the 5' and 3' ends, and contains two additional internal coding exons, compared to transcript variant 1. The encoded isoform (2) has distinct N- and C-termini, and is longer than isoform 1.

   Source sequence(s)

   AA777749, AB020665, AF330045, AK055465, AW805522, DB064574, DB227898

   Consensus CDS

   CCDS53876.1

   UniProtKB/TrEMBL

   A0A0A0MTE2, A0A8V8TKQ1

   Related

   ENSP00000433352.1, ENST00000465261.6

   Conserved Domains (5) summary

   cd00136
   Location:770 → 837

   PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

   cd16269
   Location:985 → 996

   GBP_C; coiled coil [structural motif]

   pfam15949
   Location:355 → 502

   DUF4757; Domain of unknown function (DUF4757)

   cl20817
   Location:942 → 998

   GBP_C; Guanylate-binding protein, C-terminal domain

   cl26511
   Location:943 → 1101

   Neuromodulin_N; Gap junction protein N-terminal region

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference GRCh38.p14 Primary Assembly

Genomic

1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

   Range

   75620434..75859870

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_047430323.1 → XP_047286279.1  LIM domain only protein 7 isoform X17

2. XM_047430329.1 → XP_047286285.1  LIM domain only protein 7 isoform X20

3. XM_047430352.1 → XP_047286308.1  LIM domain only protein 7 isoform X44

4. XM_047430307.1 → XP_047286263.1  LIM domain only protein 7 isoform X1

5. XM_047430308.1 → XP_047286264.1  LIM domain only protein 7 isoform X2

6. XM_047430310.1 → XP_047286266.1  LIM domain only protein 7 isoform X4

7. XM_047430309.1 → XP_047286265.1  LIM domain only protein 7 isoform X3

8. XM_047430311.1 → XP_047286267.1  LIM domain only protein 7 isoform X5

9. XM_047430312.1 → XP_047286268.1  LIM domain only protein 7 isoform X6

10. XM_047430316.1 → XP_047286272.1  LIM domain only protein 7 isoform X9

11. XM_047430317.1 → XP_047286273.1  LIM domain only protein 7 isoform X10

    UniProtKB/TrEMBL

    A0A0A0MTE2

12. XM_047430320.1 → XP_047286276.1  LIM domain only protein 7 isoform X13

13. XM_024449359.2 → XP_024305127.1  LIM domain only protein 7 isoform X14

    UniProtKB/TrEMBL

    A0A8V8TKQ1

    Conserved Domains (4) summary

    cd00136
    Location:676 → 743

    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

    cd16269
    Location:918 → 929

    GBP_C; coiled coil [structural motif]

    pfam17380
    Location:878 → 1033

    DUF5401; Family of unknown function (DUF5401)

    cl20817
    Location:875 → 931

    GBP_C; Guanylate-binding protein, C-terminal domain

14. XM_047430321.1 → XP_047286277.1  LIM domain only protein 7 isoform X15

15. XM_047430322.1 → XP_047286278.1  LIM domain only protein 7 isoform X16

16. XM_047430324.1 → XP_047286280.1  LIM domain only protein 7 isoform X18

    Related

    ENSP00000388955.1, ENST00000447038.5

17. XM_011535095.3 → XP_011533397.3  LIM domain only protein 7 isoform X22

18. XM_047430333.1 → XP_047286289.1  LIM domain only protein 7 isoform X24

19. XM_047430334.1 → XP_047286290.1  LIM domain only protein 7 isoform X25

20. XM_047430331.1 → XP_047286287.1  LIM domain only protein 7 isoform X23

21. XM_047430337.1 → XP_047286293.1  LIM domain only protein 7 isoform X28

22. XM_047430338.1 → XP_047286294.1  LIM domain only protein 7 isoform X29

23. XM_047430330.1 → XP_047286286.1  LIM domain only protein 7 isoform X21

24. XM_047430335.1 → XP_047286291.1  LIM domain only protein 7 isoform X26

25. XM_047430336.1 → XP_047286292.1  LIM domain only protein 7 isoform X27

26. XM_047430340.1 → XP_047286296.1  LIM domain only protein 7 isoform X31

27. XM_047430343.1 → XP_047286299.1  LIM domain only protein 7 isoform X34

28. XM_047430315.1 → XP_047286271.1  LIM domain only protein 7 isoform X8

29. XM_047430319.1 → XP_047286275.1  LIM domain only protein 7 isoform X12

30. XM_047430341.1 → XP_047286297.1  LIM domain only protein 7 isoform X32

31. XM_047430345.1 → XP_047286301.1  LIM domain only protein 7 isoform X37

32. XM_047430347.1 → XP_047286303.1  LIM domain only protein 7 isoform X39

33. XM_047430350.1 → XP_047286306.1  LIM domain only protein 7 isoform X42

34. XM_047430344.1 → XP_047286300.1  LIM domain only protein 7 isoform X35

35. XM_047430327.1 → XP_047286283.1  LIM domain only protein 7 isoform X17

36. XM_047430326.1 → XP_047286282.1  LIM domain only protein 7 isoform X17

37. XM_047430353.1 → XP_047286309.1  LIM domain only protein 7 isoform X45

38. XM_047430314.1 → XP_047286270.1  LIM domain only protein 7 isoform X7

39. XM_047430318.1 → XP_047286274.1  LIM domain only protein 7 isoform X11

40. XM_047430325.1 → XP_047286281.1  LIM domain only protein 7 isoform X19

41. XM_047430339.1 → XP_047286295.1  LIM domain only protein 7 isoform X30

42. XM_047430342.1 → XP_047286298.1  LIM domain only protein 7 isoform X33

43. XM_047430346.1 → XP_047286302.1  LIM domain only protein 7 isoform X38

44. XM_047430348.1 → XP_047286304.1  LIM domain only protein 7 isoform X40

45. XM_047430351.1 → XP_047286307.1  LIM domain only protein 7 isoform X43

46. XM_024449363.2 → XP_024305131.2  LIM domain only protein 7 isoform X36

    Related

    ENSP00000431129.1, ENST00000526202.5

47. XM_047430349.1 → XP_047286305.1  LIM domain only protein 7 isoform X41

48. XM_047430328.1 → XP_047286284.1  LIM domain only protein 7 isoform X17

Alternate T2T-CHM13v2.0

Genomic

1. NC_060937.1 Alternate T2T-CHM13v2.0

   Range

   74844083..75083598

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_054374537.1 → XP_054230512.1  LIM domain only protein 7 isoform X17

2. XM_054374543.1 → XP_054230518.1  LIM domain only protein 7 isoform X20

3. XM_054374567.1 → XP_054230542.1  LIM domain only protein 7 isoform X44

4. XM_054374521.1 → XP_054230496.1  LIM domain only protein 7 isoform X1

5. XM_054374522.1 → XP_054230497.1  LIM domain only protein 7 isoform X2

6. XM_054374524.1 → XP_054230499.1  LIM domain only protein 7 isoform X4

7. XM_054374523.1 → XP_054230498.1  LIM domain only protein 7 isoform X3

8. XM_054374525.1 → XP_054230500.1  LIM domain only protein 7 isoform X5

9. XM_054374526.1 → XP_054230501.1  LIM domain only protein 7 isoform X6

10. XM_054374529.1 → XP_054230504.1  LIM domain only protein 7 isoform X9

11. XM_054374530.1 → XP_054230505.1  LIM domain only protein 7 isoform X10

    UniProtKB/TrEMBL

    A0A0A0MTE2

12. XM_054374533.1 → XP_054230508.1  LIM domain only protein 7 isoform X13

13. XM_054374534.1 → XP_054230509.1  LIM domain only protein 7 isoform X14

14. XM_054374535.1 → XP_054230510.1  LIM domain only protein 7 isoform X15

15. XM_054374536.1 → XP_054230511.1  LIM domain only protein 7 isoform X16

16. XM_054374538.1 → XP_054230513.1  LIM domain only protein 7 isoform X18

17. XM_054374545.1 → XP_054230520.1  LIM domain only protein 7 isoform X22

18. XM_054374547.1 → XP_054230522.1  LIM domain only protein 7 isoform X24

19. XM_054374548.1 → XP_054230523.1  LIM domain only protein 7 isoform X25

20. XM_054374546.1 → XP_054230521.1  LIM domain only protein 7 isoform X23

21. XM_054374551.1 → XP_054230526.1  LIM domain only protein 7 isoform X28

22. XM_054374552.1 → XP_054230527.1  LIM domain only protein 7 isoform X29

23. XM_054374544.1 → XP_054230519.1  LIM domain only protein 7 isoform X21

24. XM_054374549.1 → XP_054230524.1  LIM domain only protein 7 isoform X26

25. XM_054374550.1 → XP_054230525.1  LIM domain only protein 7 isoform X27

26. XM_054374554.1 → XP_054230529.1  LIM domain only protein 7 isoform X31

27. XM_054374557.1 → XP_054230532.1  LIM domain only protein 7 isoform X34

28. XM_054374528.1 → XP_054230503.1  LIM domain only protein 7 isoform X8

29. XM_054374532.1 → XP_054230507.1  LIM domain only protein 7 isoform X12

30. XM_054374555.1 → XP_054230530.1  LIM domain only protein 7 isoform X32

31. XM_054374560.1 → XP_054230535.1  LIM domain only protein 7 isoform X37

32. XM_054374562.1 → XP_054230537.1  LIM domain only protein 7 isoform X39

33. XM_054374565.1 → XP_054230540.1  LIM domain only protein 7 isoform X42

34. XM_054374558.1 → XP_054230533.1  LIM domain only protein 7 isoform X35

35. XM_054374541.1 → XP_054230516.1  LIM domain only protein 7 isoform X17

36. XM_054374540.1 → XP_054230515.1  LIM domain only protein 7 isoform X17

37. XM_054374564.1 → XP_054230539.1  LIM domain only protein 7 isoform X41

38. XM_054374527.1 → XP_054230502.1  LIM domain only protein 7 isoform X7

39. XM_054374568.1 → XP_054230543.1  LIM domain only protein 7 isoform X45

40. XM_054374531.1 → XP_054230506.1  LIM domain only protein 7 isoform X11

41. XM_054374539.1 → XP_054230514.1  LIM domain only protein 7 isoform X19

42. XM_054374553.1 → XP_054230528.1  LIM domain only protein 7 isoform X30

43. XM_054374556.1 → XP_054230531.1  LIM domain only protein 7 isoform X33

44. XM_054374561.1 → XP_054230536.1  LIM domain only protein 7 isoform X38

45. XM_054374563.1 → XP_054230538.1  LIM domain only protein 7 isoform X40

46. XM_054374566.1 → XP_054230541.1  LIM domain only protein 7 isoform X43

47. XM_054374559.1 → XP_054230534.1  LIM domain only protein 7 isoform X36

48. XM_054374542.1 → XP_054230517.1  LIM domain only protein 7 isoform X17

The following Reference Sequences have been suppressed. Explain

These RefSeqs were suppressed for the cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links, or BLAST links (BLink), but may still be retrieved by clicking on their accession.version below.

1. NM_015843.1: Suppressed sequence

   Description

   NM_015843.1: This RefSeq was temporarily suppressed because the CDS is 5'' partial, and currently there is not sufficient data to support this transcript variant.