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MTHFS methenyltetrahydrofolate synthetase [ Gallus gallus (chicken) ]

Gene ID: 415484, updated on 5-Mar-2024

Summary

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Official Symbol
MTHFSprovided by CGNC
Official Full Name
methenyltetrahydrofolate synthetaseprovided by CGNC
Primary source
CGNC:4914
See related
Ensembl:ENSGALG00010019833
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
9
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (12654932..12687035)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (12532861..12565516)

Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene zinc finger AN1-type containing 6 Neighboring gene uncharacterized LOC112533223 Neighboring gene uncharacterized LOC124417131 Neighboring gene BCL2 related protein A1 Neighboring gene uncharacterized LOC770352 Neighboring gene membrane integral NOTCH2 associated receptor 1 Neighboring gene uncharacterized LOC121113488

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5-formyltetrahydrofolate cyclo-ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in folic acid-containing compound biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-formyltetrahydrofolate cyclo-ligase
Names
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NP_001264555.2
XP_046755013.1
XP_046780824.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277626.2 → NP_001264555.2  5-formyltetrahydrofolate cyclo-ligase

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000245
    UniProtKB/TrEMBL
    A0A8V0ZI79
    Related
    ENSGALP00010028300.1, ENSGALT00010047893.1
    Conserved Domains (1) summary
    cl00360
    Location:22 → 206
    5-FTHF_cyc-lig; 5-formyltetrahydrofolate cyclo-ligase family

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    12654932..12687035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046899057.1 → XP_046755013.1  5-formyltetrahydrofolate cyclo-ligase isoform X1

RNA

  1. XR_005862560.2 RNA Sequence

  2. XR_006931010.1 RNA Sequence

  3. XR_005862563.2 RNA Sequence

  4. XR_005862556.2 RNA Sequence

  5. XR_005862558.2 RNA Sequence

  6. XR_005862559.2 RNA Sequence

  7. XR_005862561.2 RNA Sequence

  8. XR_005862555.2 RNA Sequence

  9. XR_006931008.1 RNA Sequence

  10. XR_006931009.1 RNA Sequence

  11. XR_005862557.2 RNA Sequence

  12. XR_005862562.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    12532861..12565516
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046924868.1 → XP_046780824.1  5-formyltetrahydrofolate cyclo-ligase isoform X1

RNA

  1. XR_006935702.1 RNA Sequence

  2. XR_006935698.1 RNA Sequence

  3. XR_006935704.1 RNA Sequence

  4. XR_006935693.1 RNA Sequence

  5. XR_006935701.1 RNA Sequence

  6. XR_006935694.1 RNA Sequence

  7. XR_006935703.1 RNA Sequence

  8. XR_006935695.1 RNA Sequence

  9. XR_006935696.1 RNA Sequence

  10. XR_006935697.1 RNA Sequence

  11. XR_006935699.1 RNA Sequence

  12. XR_006935700.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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