GNAI2 G protein subunit alpha i2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: GNAI2provided by VGNC
Official Full Name: G protein subunit alpha i2provided by VGNC
Primary source: VGNC:VGNC:41302
See related: Ensembl:ENSCAFG00845022609
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	20	NC_051824.1 (39431154..39450979, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	20	NC_006602.4 (38996147..39015757, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	20	NC_049241.1 (39482556..39502160, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	20	NC_049280.1 (38798956..38818559, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	20	NC_049761.1 (39202455..39222063, complement)

Chromosome 20 - NC_051824.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Inhibition of Galpha(i) interactions in the posterior left atrium would modify the substrate for vagal atrial fibrillation.
Title: Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables G-protein beta/gamma-subunit complex binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in gamma-aminobutyric acid signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of heterotrimeric G-protein complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: guanine nucleotide-binding protein G(i) subunit alpha-2

Names: adenylate cyclase-inhibiting G alpha protein; guanine nucleotide-binding regulatory protein alpha inhibitory subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.