PTGS2 prostaglandin-endoperoxide synthase 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PTGS2provided by VGNC
Official Full Name: prostaglandin-endoperoxide synthase 2provided by VGNC
Primary source: VGNC:VGNC:6970
Locus tag: CK820_G0013506
See related: Ensembl:ENSPTRG00000001786
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	1	NC_072398.2 (62419581..62425881)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	1	NC_072398.1 (168923845..168930229, complement)

Chromosome 1 - NC_072398.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

GDB:455285 (e-PCR)
- UniSTS:157459

SHGC-76038 (e-PCR)
- UniSTS:23085

G67929 (e-PCR)
- UniSTS:225608

G67930 (e-PCR)
- UniSTS:225609

PTGS2_236 (e-PCR)
- UniSTS:280936

PTGS2-235F (e-PCR)
- UniSTS:15725

csnpptgs2-pcr10-1 (e-PCR)
- UniSTS:243111

csnpptgs2-pcr6-1 (e-PCR)
- UniSTS:243112

G63797 (e-PCR)
- UniSTS:139433

csnpptgs2-pcr8-1 (e-PCR)
- UniSTS:243113

G63795 (e-PCR)
- UniSTS:139435

G63807 (e-PCR)
- UniSTS:139436

G63794 (e-PCR)
- UniSTS:139437

G63790 (e-PCR)
- UniSTS:139439

G63789 (e-PCR)
- UniSTS:139440

G63792 (e-PCR)
- UniSTS:139441

D1S3433 (e-PCR)
- UniSTS:13489

G63793 (e-PCR)
- UniSTS:139442

G63791 (e-PCR)
- UniSTS:139443

G65466 (e-PCR)
- UniSTS:166594

G65467 (e-PCR)
- UniSTS:166595

G65468 (e-PCR)
- UniSTS:166596

G65470 (e-PCR)
- UniSTS:166598

G65471 (e-PCR)
- UniSTS:166599

G65464 (e-PCR)
- UniSTS:166600

G65465 (e-PCR)
- UniSTS:166601

PMC309638P1 (e-PCR)
- UniSTS:272598

PMC100312P2 (e-PCR)
- UniSTS:270057

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info	PubMed
enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	IEA Inferred from Electronic Annotation more info	PubMed
enables peroxidase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables prostaglandin-endoperoxide synthase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cyclooxygenase pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to oxidative stress	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in neuron projection	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prostaglandin G/H synthase 2

Names: prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

XP_524999.3

EC 1.14.99.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

62419581..62425881

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_524999.9 → XP_524999.3 prostaglandin G/H synthase 2

See identical proteins and their annotated locations for XP_524999.3

UniProtKB/TrEMBL

A0A2J8N6A4, A0A6D2XHJ5, H2Q0S9

Related

ENSPTRP00000002990.2

Conserved Domains (2) summary

cd09816
Location:75 → 562

prostaglandin_endoperoxide_synthase; Animal prostaglandin endoperoxide synthase and related bacterial proteins

cd00054
Location:19 → 54

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...