ADRB2 adrenoceptor beta 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: ADRB2provided by VGNC
Official Full Name: adrenoceptor beta 2provided by VGNC
Primary source: VGNC:VGNC:3896
Locus tag: CK820_G0010043
See related: Ensembl:ENSPTRG00000017391
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	4	NC_072402.2 (146561369..146700563)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	5	NC_072403.1 (146573878..146713077)

Chromosome 4 - NC_072402.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

GDB:606222 (e-PCR)
- UniSTS:158215

GDB:606238 (e-PCR)
- UniSTS:158219

ADRB2 (e-PCR)
- UniSTS:504882

SHGC-154600 (e-PCR)
- UniSTS:184138

PMC109640P1 (e-PCR)
- UniSTS:270173

ADRB2sts1 (e-PCR)
- UniSTS:258478

ADRB2 (e-PCR)
- UniSTS:265908

bac51348S (e-PCR)
- UniSTS:181447

PMC115184P1 (e-PCR)
- UniSTS:270293

GDB:294209 (e-PCR)
- UniSTS:156395

ADRB2_1263 (e-PCR)
- UniSTS:276979

ADRB2_v364 (e-PCR)
- UniSTS:276979

WI-19151 (e-PCR)
- UniSTS:65272

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables beta2-adrenergic receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables norepinephrine binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of smooth muscle contraction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: beta-2 adrenergic receptor

Names: adrenergic receptor beta-2; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2, surface

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001195264.3 → NP_001182193.1 beta-2 adrenergic receptor

See identical proteins and their annotated locations for NP_001182193.1

Status: VALIDATED

Source sequence(s)

JAQQLN020000004

UniProtKB/TrEMBL

A0A2J8NJB0, A0A803KKN1, D3K5P1, Q8HZG3

Conserved Domains (1) summary

cd15957
Location:34 → 336

7tmA_Beta2_AR; beta-2 adrenergic receptors (adrenoceptors), member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

146561369..146700563

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024356499.3 → XP_024212267.1 beta-2 adrenergic receptor isoform X2

UniProtKB/TrEMBL

Q8HZG3

Conserved Domains (1) summary

cd15957
Location:34 → 336

7tmA_Beta2_AR; beta-2 adrenergic receptors (adrenoceptors), member of the class A family of seven-transmembrane G protein-coupled receptors
XM_024356498.3 → XP_024212266.1 beta-2 adrenergic receptor isoform X1

UniProtKB/TrEMBL

Q8HZG3

Conserved Domains (1) summary

cd15957
Location:34 → 336

7tmA_Beta2_AR; beta-2 adrenergic receptors (adrenoceptors), member of the class A family of seven-transmembrane G protein-coupled receptors
XM_016952804.3 → XP_016808293.1 beta-2 adrenergic receptor isoform X3

UniProtKB/TrEMBL

H2QRR3, Q8HZG3

Related

ENSPTRP00000029722.5