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ADCY4 adenylate cyclase 4 [ Canis lupus familiaris (dog) ]

Gene ID: 480271, updated on 5-Mar-2024

Summary

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Official Symbol
ADCY4provided by VGNC
Official Full Name
adenylate cyclase 4provided by VGNC
Primary source
VGNC:VGNC:37621
See related
Ensembl:ENSCAFG00845007125
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ADCY4 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
26
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (4399506..4415189, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (4210485..4226167, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (4414264..4429941, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (4089855..4105524, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (4151682..4167531, complement)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene cell death inducing DFFA like effector b Neighboring gene leukotriene B4 receptor 2 Neighboring gene leukotriene B4 receptor Neighboring gene receptor interacting serine/threonine kinase 3 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables adenylate cyclase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cAMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adenylate cyclase type 4
XP_005623330.1
XP_013971276.1
XP_013971277.1
XP_022277561.1
XP_022277563.1
XP_038338820.1
XP_038338821.1
XP_038338822.1
XP_038338823.1
XP_038338824.1
XP_038338825.1
XP_038338826.1
XP_038400253.1
XP_038400254.1
XP_038400255.1
XP_038400256.1
XP_038400257.1
XP_038400258.1
XP_038400259.1
XP_038440229.1
XP_038464370.1
XP_038464371.1
XP_038464372.1
XP_038464373.1
XP_038464374.1
XP_038464375.1
XP_038464376.1
XP_038529182.1
XP_038529183.1
XP_038529184.1
XP_038529185.1
XP_038529186.1
XP_038529187.1
XP_038529188.1
XP_537394.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    4399506..4415189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038673260.1 → XP_038529188.1  adenylate cyclase type 4 isoform X7

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:788 → 1012
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:1 → 114
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:403 → 507
    DUF1053; Domain of Unknown Function (DUF1053)

  2. XM_038673254.1 → XP_038529182.1  adenylate cyclase type 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:920 → 1144
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:535 → 639
    DUF1053; Domain of Unknown Function (DUF1053)

  3. XM_038673259.1 → XP_038529187.1  adenylate cyclase type 4 isoform X6

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (4) summary
    pfam00211
    Location:830 → 1054
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:445 → 549
    DUF1053; Domain of Unknown Function (DUF1053)
    cl11967
    Location:328 → 384
    Nucleotidyl_cyc_III; Class III nucleotidyl cyclases

  4. XM_038673256.1 → XP_038529184.1  adenylate cyclase type 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:885 → 1109
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:500 → 604
    DUF1053; Domain of Unknown Function (DUF1053)

  5. XM_038673255.1 → XP_038529183.1  adenylate cyclase type 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:920 → 1119
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:535 → 639
    DUF1053; Domain of Unknown Function (DUF1053)

  6. XM_038673257.1 → XP_038529185.1  adenylate cyclase type 4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:864 → 1088
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:479 → 583
    DUF1053; Domain of Unknown Function (DUF1053)

  7. XM_038673258.1 → XP_038529186.1  adenylate cyclase type 4 isoform X5

    UniProtKB/TrEMBL
    A0A8C0LKP6, A0A8C0N4S7, A0A8I3RTR3
    Related
    ENSCAFP00845009870.1, ENSCAFT00845012649.1
    Conserved Domains (3) summary
    pfam00211
    Location:864 → 1063
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:479 → 583
    DUF1053; Domain of Unknown Function (DUF1053)

RNA

  1. XR_005430822.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    4089855..4105524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038482898.1 → XP_038338826.1  adenylate cyclase type 4 isoform X7

    Conserved Domains (3) summary
    pfam00211
    Location:788 → 1012
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:1 → 114
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:403 → 507
    DUF1053; Domain of Unknown Function (DUF1053)

  2. XM_038482897.1 → XP_038338825.1  adenylate cyclase type 4 isoform X6

    Conserved Domains (4) summary
    pfam00211
    Location:830 → 1054
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:445 → 549
    DUF1053; Domain of Unknown Function (DUF1053)
    cl11967
    Location:328 → 384
    Nucleotidyl_cyc_III; Class III nucleotidyl cyclases

  3. XM_038482892.1 → XP_038338820.1  adenylate cyclase type 4 isoform X1

    Conserved Domains (3) summary
    pfam00211
    Location:920 → 1144
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:535 → 639
    DUF1053; Domain of Unknown Function (DUF1053)

  4. XM_038482894.1 → XP_038338822.1  adenylate cyclase type 4 isoform X3

    Conserved Domains (3) summary
    pfam00211
    Location:885 → 1109
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:500 → 604
    DUF1053; Domain of Unknown Function (DUF1053)

  5. XM_038482893.1 → XP_038338821.1  adenylate cyclase type 4 isoform X2

    Conserved Domains (3) summary
    pfam00211
    Location:920 → 1119
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:535 → 639
    DUF1053; Domain of Unknown Function (DUF1053)

  6. XM_038482895.1 → XP_038338823.1  adenylate cyclase type 4 isoform X4

    Conserved Domains (3) summary
    pfam00211
    Location:864 → 1088
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:479 → 583
    DUF1053; Domain of Unknown Function (DUF1053)

  7. XM_038482896.1 → XP_038338824.1  adenylate cyclase type 4 isoform X5

    Conserved Domains (3) summary
    pfam00211
    Location:864 → 1063
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:479 → 583
    DUF1053; Domain of Unknown Function (DUF1053)

RNA

  1. XR_005329202.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    4151682..4167531 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038608448.1 → XP_038464376.1  adenylate cyclase type 4 isoform X7

    Conserved Domains (3) summary
    pfam00211
    Location:788 → 1012
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:1 → 114
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:403 → 507
    DUF1053; Domain of Unknown Function (DUF1053)

  2. XM_038608447.1 → XP_038464375.1  adenylate cyclase type 4 isoform X6

    Conserved Domains (4) summary
    pfam00211
    Location:830 → 1054
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:445 → 549
    DUF1053; Domain of Unknown Function (DUF1053)
    cl11967
    Location:328 → 384
    Nucleotidyl_cyc_III; Class III nucleotidyl cyclases

  3. XM_038608442.1 → XP_038464370.1  adenylate cyclase type 4 isoform X1

    Conserved Domains (3) summary
    pfam00211
    Location:920 → 1144
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:535 → 639
    DUF1053; Domain of Unknown Function (DUF1053)

  4. XM_038608444.1 → XP_038464372.1  adenylate cyclase type 4 isoform X3

    Conserved Domains (3) summary
    pfam00211
    Location:885 → 1109
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:500 → 604
    DUF1053; Domain of Unknown Function (DUF1053)

  5. XM_038608443.1 → XP_038464371.1  adenylate cyclase type 4 isoform X2

    Conserved Domains (3) summary
    pfam00211
    Location:920 → 1119
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:535 → 639
    DUF1053; Domain of Unknown Function (DUF1053)

  6. XM_038608445.1 → XP_038464373.1  adenylate cyclase type 4 isoform X4

    Conserved Domains (3) summary
    pfam00211
    Location:864 → 1088
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:479 → 583
    DUF1053; Domain of Unknown Function (DUF1053)

  7. XM_038608446.1 → XP_038464374.1  adenylate cyclase type 4 isoform X5

    Conserved Domains (3) summary
    pfam00211
    Location:864 → 1063
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:479 → 583
    DUF1053; Domain of Unknown Function (DUF1053)

RNA

  1. XR_005397544.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    4414264..4429941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038544331.1 → XP_038400259.1  adenylate cyclase type 4 isoform X7

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:788 → 1012
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:1 → 114
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:403 → 507
    DUF1053; Domain of Unknown Function (DUF1053)

  2. XM_038544330.1 → XP_038400258.1  adenylate cyclase type 4 isoform X6

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (4) summary
    pfam00211
    Location:830 → 1054
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:445 → 549
    DUF1053; Domain of Unknown Function (DUF1053)
    cl11967
    Location:328 → 384
    Nucleotidyl_cyc_III; Class III nucleotidyl cyclases

  3. XM_038544325.1 → XP_038400253.1  adenylate cyclase type 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:920 → 1144
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:535 → 639
    DUF1053; Domain of Unknown Function (DUF1053)

  4. XM_038544327.1 → XP_038400255.1  adenylate cyclase type 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:885 → 1109
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:500 → 604
    DUF1053; Domain of Unknown Function (DUF1053)

  5. XM_038544326.1 → XP_038400254.1  adenylate cyclase type 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:920 → 1119
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:535 → 639
    DUF1053; Domain of Unknown Function (DUF1053)

  6. XM_038544328.1 → XP_038400256.1  adenylate cyclase type 4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:864 → 1088
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:479 → 583
    DUF1053; Domain of Unknown Function (DUF1053)

  7. XM_038544329.1 → XP_038400257.1  adenylate cyclase type 4 isoform X5

    UniProtKB/TrEMBL
    A0A8C0LKP6, A0A8C0N4S7, A0A8I3RTR3
    Conserved Domains (3) summary
    pfam00211
    Location:864 → 1063
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:479 → 583
    DUF1053; Domain of Unknown Function (DUF1053)

RNA

  1. XR_005363073.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    4210485..4226167 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022421855.2 → XP_022277563.1  adenylate cyclase type 4 isoform X7

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:788 → 1012
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:1 → 114
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:403 → 507
    DUF1053; Domain of Unknown Function (DUF1053)

  2. XM_022421853.2 → XP_022277561.1  adenylate cyclase type 4 isoform X6

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (4) summary
    pfam00211
    Location:830 → 1054
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:445 → 549
    DUF1053; Domain of Unknown Function (DUF1053)
    cl11967
    Location:328 → 384
    Nucleotidyl_cyc_III; Class III nucleotidyl cyclases

  3. XM_014115801.3 → XP_013971276.1  adenylate cyclase type 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:920 → 1144
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:535 → 639
    DUF1053; Domain of Unknown Function (DUF1053)

  4. XM_038584301.1 → XP_038440229.1  adenylate cyclase type 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:885 → 1109
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:500 → 604
    DUF1053; Domain of Unknown Function (DUF1053)

  5. XM_005623273.3 → XP_005623330.1  adenylate cyclase type 4 isoform X2

    See identical proteins and their annotated locations for XP_005623330.1

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:920 → 1119
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:535 → 639
    DUF1053; Domain of Unknown Function (DUF1053)

  6. XM_014115802.2 → XP_013971277.1  adenylate cyclase type 4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LKP6
    Conserved Domains (3) summary
    pfam00211
    Location:864 → 1088
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:479 → 583
    DUF1053; Domain of Unknown Function (DUF1053)

  7. XM_537394.6 → XP_537394.2  adenylate cyclase type 4 isoform X5

    UniProtKB/TrEMBL
    A0A8C0LKP6, A0A8C0N4S7, A0A8I3RTR3
    Conserved Domains (3) summary
    pfam00211
    Location:864 → 1063
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:115 → 246
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:479 → 583
    DUF1053; Domain of Unknown Function (DUF1053)

RNA

  1. XR_005384412.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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