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ADCY8 adenylate cyclase 8 [ Canis lupus familiaris (dog) ]

Gene ID: 482045, updated on 5-Mar-2024

Summary

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Official Symbol
ADCY8provided by VGNC
Official Full Name
adenylate cyclase 8provided by VGNC
Primary source
VGNC:VGNC:37625
See related
Ensembl:ENSCAFG00845013615
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ADCY8 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (28068919..28289497, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (27690009..27910417, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (28205442..28426573, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (27784095..28006367, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (27904105..28118318, complement)

Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098554 Neighboring gene uncharacterized LOC111098451 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111098452 Neighboring gene uncharacterized LOC119865419

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables adenylate cyclase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cAMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adenylate cyclase type 8
XP_005627997.1
XP_005627998.2
XP_038349201.1
XP_038349202.1
XP_038349203.1
XP_038411460.1
XP_038411461.1
XP_038411462.1
XP_038475359.1
XP_038475360.1
XP_038475361.1
XP_038540963.1
XP_038540964.1
XP_038540965.1
XP_539166.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051817.1 Reference ROS_Cfam_1.0

    Range
    28068919..28289497 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038685036.1 → XP_038540964.1  adenylate cyclase type 8 isoform X2

    UniProtKB/TrEMBL
    A0A8C0T647, A0A8I3NUB8, A0A8I3NUE6, A0A8P0TJP9
    Related
    ENSCAFP00845019551.1, ENSCAFT00845024853.1
    Conserved Domains (3) summary
    pfam00211
    Location:943 → 1142
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:161 → 400
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:617 → 711
    DUF1053; Domain of Unknown Function (DUF1053)

  2. XM_038685035.1 → XP_038540963.1  adenylate cyclase type 8 isoform X1

    UniProtKB/TrEMBL
    A0A8C0Z1L3, A0A8I3NFX0, A0A8I3NUE6, A0A8P0TJP9
    Related
    ENSCAFP00845019509.1, ENSCAFT00845024802.1
    Conserved Domains (3) summary
    pfam00211
    Location:973 → 1172
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:161 → 400
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:617 → 711
    DUF1053; Domain of Unknown Function (DUF1053)

  3. XM_038685037.1 → XP_038540965.1  adenylate cyclase type 8 isoform X3

    UniProtKB/TrEMBL
    A0A8C0T467, A0A8I3NUA5
    Related
    ENSCAFP00845019629.1, ENSCAFT00845024954.1
    Conserved Domains (2) summary
    pfam00211
    Location:723 → 922
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:89 → 216
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049273.1 Alternate UMICH_Zoey_3.1

    Range
    27784095..28006367 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038493274.1 → XP_038349202.1  adenylate cyclase type 8 isoform X2

    Conserved Domains (3) summary
    pfam00211
    Location:943 → 1142
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:161 → 400
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:617 → 711
    DUF1053; Domain of Unknown Function (DUF1053)

  2. XM_038493273.1 → XP_038349201.1  adenylate cyclase type 8 isoform X1

    Conserved Domains (3) summary
    pfam00211
    Location:973 → 1172
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:161 → 400
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:617 → 711
    DUF1053; Domain of Unknown Function (DUF1053)

  3. XM_038493275.1 → XP_038349203.1  adenylate cyclase type 8 isoform X3

    Conserved Domains (2) summary
    pfam00211
    Location:723 → 922
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:89 → 216
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

    Range
    27904105..28118318 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038619432.1 → XP_038475360.1  adenylate cyclase type 8 isoform X2

  2. XM_038619431.1 → XP_038475359.1  adenylate cyclase type 8 isoform X1

  3. XM_038619433.1 → XP_038475361.1  adenylate cyclase type 8 isoform X3

    Conserved Domains (2) summary
    pfam00211
    Location:723 → 922
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:89 → 216
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

    Range
    28205442..28426573 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038555533.1 → XP_038411461.1  adenylate cyclase type 8 isoform X2

    UniProtKB/TrEMBL
    A0A8C0T647, A0A8I3NUB8, A0A8I3NUE6, A0A8P0TJP9
    Conserved Domains (3) summary
    pfam00211
    Location:943 → 1142
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:161 → 400
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:617 → 711
    DUF1053; Domain of Unknown Function (DUF1053)

  2. XM_038555532.1 → XP_038411460.1  adenylate cyclase type 8 isoform X1

    UniProtKB/TrEMBL
    A0A8C0Z1L3, A0A8I3NFX0, A0A8I3NUE6, A0A8P0TJP9
    Conserved Domains (3) summary
    pfam00211
    Location:973 → 1172
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:161 → 400
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:617 → 711
    DUF1053; Domain of Unknown Function (DUF1053)

  3. XM_038555534.1 → XP_038411462.1  adenylate cyclase type 8 isoform X3

    UniProtKB/TrEMBL
    A0A8C0T467, A0A8I3NUA5
    Conserved Domains (2) summary
    pfam00211
    Location:723 → 922
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:89 → 216
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    27690009..27910417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005627940.4 → XP_005627997.1  adenylate cyclase type 8 isoform X2

    UniProtKB/TrEMBL
    A0A8C0T647, A0A8I3NUB8, A0A8I3NUE6, A0A8P0TJP9
    Conserved Domains (3) summary
    pfam00211
    Location:943 → 1142
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:161 → 400
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:617 → 711
    DUF1053; Domain of Unknown Function (DUF1053)

  2. XM_539166.7 → XP_539166.2  adenylate cyclase type 8 isoform X1

    UniProtKB/TrEMBL
    A0A8C0Z1L3, A0A8I3NFX0, A0A8I3NUE6, A0A8P0TJP9
    Conserved Domains (3) summary
    pfam00211
    Location:973 → 1172
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:161 → 400
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    pfam06327
    Location:617 → 711
    DUF1053; Domain of Unknown Function (DUF1053)

  3. XM_005627941.4 → XP_005627998.2  adenylate cyclase type 8 isoform X3

    UniProtKB/TrEMBL
    A0A8C0T467, A0A8I3NUA5
    Conserved Domains (2) summary
    pfam00211
    Location:723 → 922
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:89 → 216
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
Nucleotide Protein
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