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LTA4H leukotriene A4 hydrolase [ Canis lupus familiaris (dog) ]

Gene ID: 482611, updated on 5-Mar-2024

Summary

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Official Symbol
LTA4Hprovided by VGNC
Official Full Name
leukotriene A4 hydrolaseprovided by VGNC
Primary source
VGNC:VGNC:42853
See related
Ensembl:ENSCAFG00845024692
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
19
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (36460885..36495697, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (36182408..36217145, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (36091485..36126289, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (35733722..35768521, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (35828282..35863043, complement)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene amidohydrolase domain containing 1 Neighboring gene histidine ammonia-lyase Neighboring gene uncharacterized LOC102152760 Neighboring gene transfer RNA aspartic acid (anticodon GUC) Neighboring gene uncharacterized LOC111090047

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aminopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables epoxide hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables leukotriene-A4 hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in leukotriene biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leukotriene A-4 hydrolase
XP_038352245.1
XP_038414629.1
XP_038478545.1
XP_038544216.1
XP_539728.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    36460885..36495697 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038688288.1 → XP_038544216.1  leukotriene A-4 hydrolase

    UniProtKB/TrEMBL
    A0A8I3PTW1
    Related
    ENSCAFP00845034446.1, ENSCAFT00845043953.1
    Conserved Domains (1) summary
    TIGR02411
    Location:6 → 608
    leuko_A4_hydro; leukotriene A-4 hydrolase/aminopeptidase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    35733722..35768521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496317.1 → XP_038352245.1  leukotriene A-4 hydrolase

    Conserved Domains (1) summary
    TIGR02411
    Location:6 → 608
    leuko_A4_hydro; leukotriene A-4 hydrolase/aminopeptidase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    35828282..35863043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038622617.1 → XP_038478545.1  leukotriene A-4 hydrolase

    Conserved Domains (1) summary
    TIGR02411
    Location:6 → 608
    leuko_A4_hydro; leukotriene A-4 hydrolase/aminopeptidase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    36091485..36126289 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558701.1 → XP_038414629.1  leukotriene A-4 hydrolase

    UniProtKB/TrEMBL
    A0A8I3PTW1
    Conserved Domains (1) summary
    TIGR02411
    Location:6 → 608
    leuko_A4_hydro; leukotriene A-4 hydrolase/aminopeptidase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    36182408..36217145 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_539728.7 → XP_539728.3  leukotriene A-4 hydrolase

    UniProtKB/TrEMBL
    A0A8I3PTW1
    Conserved Domains (1) summary
    TIGR02411
    Location:6 → 608
    leuko_A4_hydro; leukotriene A-4 hydrolase/aminopeptidase
Nucleotide Protein
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