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APAF1 apoptotic peptidase activating factor 1 [ Canis lupus familiaris (dog) ]

Gene ID: 482620, updated on 5-Mar-2024

Summary

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Official Symbol
APAF1provided by VGNC
Official Full Name
apoptotic peptidase activating factor 1provided by VGNC
Primary source
VGNC:VGNC:54194
See related
Ensembl:ENSCAFG00845027232
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
APAF-1
Orthologs
human mouse all
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Genomic context

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See APAF1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
46
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (38689945..38835971)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (38408276..38554051)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (38328187..38474238)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (37961882..38107501)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (38054503..38200556)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA53 Neighboring gene translation initiation factor IF-2-like Neighboring gene small nucleolar RNA SNORA70 Neighboring gene solute carrier family 25 member 3 Neighboring gene IKBKB interacting protein Neighboring gene uncharacterized LOC119869417 Neighboring gene uncharacterized LOC111090058 Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1B Neighboring gene cytosolic purine 5'-nucleotidase-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of apoptosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
apoptotic protease-activating factor 1
Names
Apoptotic protease-activating factor 1
apoptotic protease activating factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    38689945..38835971
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038688353.1 → XP_038544281.1  apoptotic protease-activating factor 1 isoform X7

    UniProtKB/TrEMBL
    A0A8C0QM80, A0A8C0R713, A0A8I3S699
    Conserved Domains (5) summary
    cd00200
    Location:608 → 1017
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  2. XM_038688349.1 → XP_038544277.1  apoptotic protease-activating factor 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0NT42
    Conserved Domains (6) summary
    COG2319
    Location:837 → 1187
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  3. XM_038688351.1 → XP_038544279.1  apoptotic protease-activating factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QM80, A0A8C0R713, A0A8I3S699
    Conserved Domains (5) summary
    cd00200
    Location:608 → 934
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:661 → 698
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  4. XM_038688350.1 → XP_038544278.1  apoptotic protease-activating factor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0P0S4
    Conserved Domains (5) summary
    cd00200
    Location:608 → 869
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:661 → 698
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  5. XM_038688352.1 → XP_038544280.1  apoptotic protease-activating factor 1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0NT42
    Conserved Domains (5) summary
    cd00200
    Location:552 → 855
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:568 → 600
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:399 → 532
    APAF1_C; APAF-1 helical domain

  6. XM_038688346.1 → XP_038544274.1  apoptotic protease-activating factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NT42
    Conserved Domains (5) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  7. XM_038688348.1 → XP_038544276.1  apoptotic protease-activating factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LEF9, A0A8C0LFC7, A0A8C0P040, A0A8I3PSY9
    Related
    ENSCAFP00845037757.1, ENSCAFT00845048127.1
    Conserved Domains (5) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  8. XM_038688354.1 → XP_038544282.1  apoptotic protease-activating factor 1 isoform X8

    UniProtKB/TrEMBL
    A0A8C0LHN3, A0A8I3Q1H0, A0A8P0SR49
    Conserved Domains (6) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain
    cl29593
    Location:837 → 1069
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  9. XM_038688356.1 → XP_038544284.1  apoptotic protease-activating factor 1 isoform X10

    Conserved Domains (5) summary
    cd00200
    Location:608 → 769
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:620 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  10. XM_038688347.1 → XP_038544275.1  apoptotic protease-activating factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NT42
    Conserved Domains (5) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  11. XM_038688355.1 → XP_038544283.1  apoptotic protease-activating factor 1 isoform X9

    Conserved Domains (4) summary
    cd00200
    Location:378 → 681
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:394 → 426
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:2 → 145
    NB-ARC; NB-ARC domain
    pfam17908
    Location:224 → 358
    APAF1_C; APAF-1 helical domain

RNA

  1. XR_005438387.1 RNA Sequence

  2. XR_005438386.1 RNA Sequence

  3. XR_005438389.1 RNA Sequence

  4. XR_005438388.1 RNA Sequence

  5. XR_005438393.1 RNA Sequence

  6. XR_005438392.1 RNA Sequence

  7. XR_005438391.1 RNA Sequence

  8. XR_005438390.1 RNA Sequence

  9. XR_005438394.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    37961882..38107501
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496365.1 → XP_038352293.1  apoptotic protease-activating factor 1 isoform X7

    Conserved Domains (5) summary
    cd00200
    Location:608 → 1017
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  2. XM_038496360.1 → XP_038352288.1  apoptotic protease-activating factor 1 isoform X3

    Conserved Domains (6) summary
    COG2319
    Location:837 → 1187
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  3. XM_038496362.1 → XP_038352290.1  apoptotic protease-activating factor 1 isoform X5

    Conserved Domains (5) summary
    cd00200
    Location:608 → 934
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:661 → 698
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  4. XM_038496361.1 → XP_038352289.1  apoptotic protease-activating factor 1 isoform X4

    Conserved Domains (5) summary
    cd00200
    Location:608 → 869
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:661 → 698
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  5. XM_038496363.1 → XP_038352291.1  apoptotic protease-activating factor 1 isoform X6

    Conserved Domains (5) summary
    cd00200
    Location:552 → 855
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:568 → 600
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:399 → 532
    APAF1_C; APAF-1 helical domain

  6. XM_038496357.1 → XP_038352285.1  apoptotic protease-activating factor 1 isoform X1

    Conserved Domains (5) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  7. XM_038496359.1 → XP_038352287.1  apoptotic protease-activating factor 1 isoform X2

    Conserved Domains (5) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  8. XM_038496366.1 → XP_038352294.1  apoptotic protease-activating factor 1 isoform X8

    Conserved Domains (6) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain
    cl29593
    Location:837 → 1069
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  9. XM_038496368.1 → XP_038352296.1  apoptotic protease-activating factor 1 isoform X10

    Conserved Domains (5) summary
    cd00200
    Location:608 → 769
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:620 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  10. XM_038496358.1 → XP_038352286.1  apoptotic protease-activating factor 1 isoform X1

    Conserved Domains (5) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  11. XM_038496367.1 → XP_038352295.1  apoptotic protease-activating factor 1 isoform X9

    Conserved Domains (4) summary
    cd00200
    Location:378 → 681
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:394 → 426
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:2 → 145
    NB-ARC; NB-ARC domain
    pfam17908
    Location:224 → 358
    APAF1_C; APAF-1 helical domain

RNA

  1. XR_005336881.1 RNA Sequence

  2. XR_005336880.1 RNA Sequence

  3. XR_005336884.1 RNA Sequence

  4. XR_005336882.1 RNA Sequence

  5. XR_005336888.1 RNA Sequence

  6. XR_005336887.1 RNA Sequence

  7. XR_005336886.1 RNA Sequence

  8. XR_005336885.1 RNA Sequence

  9. XR_005336889.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    38054503..38200556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038622689.1 → XP_038478617.1  apoptotic protease-activating factor 1 isoform X7

  2. XM_038622685.1 → XP_038478613.1  apoptotic protease-activating factor 1 isoform X3

  3. XM_038622687.1 → XP_038478615.1  apoptotic protease-activating factor 1 isoform X5

  4. XM_038622686.1 → XP_038478614.1  apoptotic protease-activating factor 1 isoform X4

  5. XM_038622688.1 → XP_038478616.1  apoptotic protease-activating factor 1 isoform X6

  6. XM_038622682.1 → XP_038478610.1  apoptotic protease-activating factor 1 isoform X1

  7. XM_038622684.1 → XP_038478612.1  apoptotic protease-activating factor 1 isoform X2

    Conserved Domains (5) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  8. XM_038622690.1 → XP_038478618.1  apoptotic protease-activating factor 1 isoform X8

    Conserved Domains (6) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain
    cl29593
    Location:837 → 1069
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  9. XM_038622692.1 → XP_038478620.1  apoptotic protease-activating factor 1 isoform X10

    Conserved Domains (5) summary
    cd00200
    Location:608 → 769
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:620 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  10. XM_038622683.1 → XP_038478611.1  apoptotic protease-activating factor 1 isoform X1

  11. XM_038622691.1 → XP_038478619.1  apoptotic protease-activating factor 1 isoform X9

RNA

  1. XR_005404848.1 RNA Sequence

  2. XR_005404847.1 RNA Sequence

  3. XR_005404850.1 RNA Sequence

  4. XR_005404849.1 RNA Sequence

  5. XR_005404854.1 RNA Sequence

  6. XR_005404853.1 RNA Sequence

  7. XR_005404852.1 RNA Sequence

  8. XR_005404851.1 RNA Sequence

  9. XR_005404856.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    38328187..38474238
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558766.1 → XP_038414694.1  apoptotic protease-activating factor 1 isoform X7

    UniProtKB/TrEMBL
    A0A8C0QM80, A0A8C0R713, A0A8I3S699

  2. XM_038558762.1 → XP_038414690.1  apoptotic protease-activating factor 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0NT42

  3. XM_038558764.1 → XP_038414692.1  apoptotic protease-activating factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QM80, A0A8C0R713, A0A8I3S699

  4. XM_038558763.1 → XP_038414691.1  apoptotic protease-activating factor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0P0S4

  5. XM_038558765.1 → XP_038414693.1  apoptotic protease-activating factor 1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0NT42

  6. XM_038558759.1 → XP_038414687.1  apoptotic protease-activating factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NT42

  7. XM_038558761.1 → XP_038414689.1  apoptotic protease-activating factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LEF9, A0A8C0LFC7, A0A8C0P040, A0A8I3PSY9
    Conserved Domains (5) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  8. XM_038558767.1 → XP_038414695.1  apoptotic protease-activating factor 1 isoform X8

    UniProtKB/TrEMBL
    A0A8C0LHN3, A0A8I3Q1H0, A0A8P0SR49
    Conserved Domains (6) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain
    cl29593
    Location:837 → 1069
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  9. XM_038558769.1 → XP_038414697.1  apoptotic protease-activating factor 1 isoform X10

    Conserved Domains (5) summary
    cd00200
    Location:608 → 769
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:620 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  10. XM_038558760.1 → XP_038414688.1  apoptotic protease-activating factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NT42

  11. XM_038558768.1 → XP_038414696.1  apoptotic protease-activating factor 1 isoform X9

RNA

  1. XR_005370661.1 RNA Sequence

  2. XR_005370660.1 RNA Sequence

  3. XR_005370663.1 RNA Sequence

  4. XR_005370662.1 RNA Sequence

  5. XR_005370667.1 RNA Sequence

  6. XR_005370666.1 RNA Sequence

  7. XR_005370665.1 RNA Sequence

  8. XR_005370664.1 RNA Sequence

  9. XR_005370668.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    38408276..38554051
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038452196.1 → XP_038308124.1  apoptotic protease-activating factor 1 isoform X10

    Conserved Domains (5) summary
    cd00200
    Location:608 → 769
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:620 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  2. XM_038452194.1 → XP_038308122.1  apoptotic protease-activating factor 1 isoform X7

    UniProtKB/TrEMBL
    A0A8C0QM80, A0A8C0R713, A0A8I3S699
    Conserved Domains (5) summary
    cd00200
    Location:608 → 1017
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  3. XM_038452190.1 → XP_038308118.1  apoptotic protease-activating factor 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0NT42
    Conserved Domains (6) summary
    COG2319
    Location:837 → 1187
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  4. XM_038452192.1 → XP_038308120.1  apoptotic protease-activating factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QM80, A0A8C0R713, A0A8I3S699
    Conserved Domains (5) summary
    cd00200
    Location:608 → 934
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:661 → 698
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  5. XM_038452191.1 → XP_038308119.1  apoptotic protease-activating factor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0P0S4
    Conserved Domains (5) summary
    cd00200
    Location:608 → 869
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:661 → 698
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  6. XM_038452193.1 → XP_038308121.1  apoptotic protease-activating factor 1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0NT42
    Conserved Domains (5) summary
    cd00200
    Location:552 → 855
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:568 → 600
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:399 → 532
    APAF1_C; APAF-1 helical domain

  7. XM_038452188.1 → XP_038308116.1  apoptotic protease-activating factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NT42
    Conserved Domains (5) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  8. XM_038452195.1 → XP_038308123.1  apoptotic protease-activating factor 1 isoform X8

    UniProtKB/TrEMBL
    A0A8C0LHN3, A0A8I3Q1H0, A0A8P0SR49
    Conserved Domains (6) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain
    cl29593
    Location:837 → 1069
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  9. XM_038452189.1 → XP_038308117.1  apoptotic protease-activating factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LEF9, A0A8C0LFC7, A0A8C0P040, A0A8I3PSY9
    Conserved Domains (5) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  10. XM_022403383.2 → XP_022259091.1  apoptotic protease-activating factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NT42
    Conserved Domains (5) summary
    cd00200
    Location:608 → 911
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:624 → 656
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:130 → 375
    NB-ARC; NB-ARC domain
    pfam17908
    Location:454 → 588
    APAF1_C; APAF-1 helical domain

  11. XM_022403390.2 → XP_022259098.1  apoptotic protease-activating factor 1 isoform X9

    Conserved Domains (3) summary
    cd00200
    Location:378 → 681
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:394 → 426
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:2 → 185
    NB-ARC; NB-ARC domain

RNA

  1. XR_005310455.1 RNA Sequence

  2. XR_005310454.1 RNA Sequence

  3. XR_005310457.1 RNA Sequence

  4. XR_005310456.1 RNA Sequence

  5. XR_005310461.1 RNA Sequence

  6. XR_005310460.1 RNA Sequence

  7. XR_005310459.1 RNA Sequence

  8. XR_005310458.1 RNA Sequence

  9. XR_005310462.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9GL23.2 GenPept UniProtKB/Swiss-Prot:Q9GL23

Gene LinkOut

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