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EPOR erythropoietin receptor [ Canis lupus familiaris (dog) ]

Gene ID: 484943, updated on 5-Mar-2024

Summary

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Official Symbol
EPORprovided by VGNC
Official Full Name
erythropoietin receptorprovided by VGNC
Primary source
VGNC:VGNC:40424
See related
Ensembl:ENSCAFG00845019440
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
EPO-R
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (50463402..50469165)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (49816892..49821971)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (50343701..50348780)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (49674383..49679467)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (50100740..50105821)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119864739 Neighboring gene outer dynein arm docking complex subunit 3 Neighboring gene ral guanine nucleotide dissociation stimulator like 3 Neighboring gene uncharacterized LOC111091374 Neighboring gene SWIM-type zinc finger 7 associated protein 1 Neighboring gene phospholipid phosphatase related 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Synergistic upregulation of erythropoietin receptor (EPO-R) expression by sense and antisense EPO-R transcripts in the canine lung. Zhang Q, et al. Proc Natl Acad Sci U S A, 2008 May 27. PMID 18495932, Free PMC Article
  2. Upregulation of erythropoietin receptor during postnatal and postpneumonectomy lung growth. Foster DJ, et al. Am J Physiol Lung Cell Mol Physiol, 2004 Dec. PMID 15286000

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. sEPO-R and asEPO-R transcripts contribute to in vivo up-regulation of EPO-R protein expression in the post-pneumonectomy remaining lung.
    Title: Synergistic upregulation of erythropoietin receptor (EPO-R) expression by sense and antisense EPO-R transcripts in the canine lung.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables erythropoietin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hemopoiesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
erythropoietin receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001048111.1 → NP_001041576.1  erythropoietin receptor precursor

    See identical proteins and their annotated locations for NP_001041576.1

    Status: PROVISIONAL

    Source sequence(s)
    AY908987
    UniProtKB/Swiss-Prot
    Q2KL21
    UniProtKB/TrEMBL
    A0A8C0RQI3
    Related
    ENSCAFP00845026848.1, ENSCAFT00845034299.1
    Conserved Domains (2) summary
    cd00063
    Location:147 → 244
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam09067
    Location:37 → 141
    EpoR_lig-bind; Erythropoietin receptor, ligand binding

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    50463402..50469165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038426476.1 → XP_038282404.1  erythropoietin receptor isoform X1

    UniProtKB/TrEMBL
    A0A8C0RQI3, A0A8I3P4L4, A0A8P0NIT0
    Conserved Domains (2) summary
    cd00063
    Location:147 → 244
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam09067
    Location:37 → 141
    EpoR_lig-bind; Erythropoietin receptor, ligand binding

  2. XM_038426478.1 → XP_038282406.1  erythropoietin receptor isoform X2

    Conserved Domains (2) summary
    cd00063
    Location:147 → 244
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam09067
    Location:37 → 141
    EpoR_lig-bind; Erythropoietin receptor, ligand binding

  3. XM_038426477.1 → XP_038282405.1  erythropoietin receptor isoform X1

    UniProtKB/TrEMBL
    A0A8C0RQI3, A0A8I3P4L4, A0A8P0NIT0
    Conserved Domains (2) summary
    cd00063
    Location:147 → 244
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam09067
    Location:37 → 141
    EpoR_lig-bind; Erythropoietin receptor, ligand binding

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    49674383..49679467
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    50100740..50105821
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    50343701..50348780
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    49816892..49821971
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2KL21.1 GenPept UniProtKB/Swiss-Prot:Q2KL21

Gene LinkOut

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