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FZD3 frizzled class receptor 3 [ Canis lupus familiaris (dog) ]

Gene ID: 486093, updated on 5-Mar-2024

Summary

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Official Symbol
FZD3provided by VGNC
Official Full Name
frizzled class receptor 3provided by VGNC
Primary source
VGNC:VGNC:41031
See related
Ensembl:ENSCAFG00845022244
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See FZD3 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
13
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (29127606..29234347, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (29618932..29725782, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (29137221..29244439, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (29087452..29194695, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (28971836..29078759, complement)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene integrator complex subunit 9 Neighboring gene exostosin like glycosyltransferase 3 Neighboring gene U2 spliceosomal RNA Neighboring gene F-box protein 16 Neighboring gene zinc finger protein 395

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
frizzled-3
Names
frizzled 3, seven transmembrane spanning receptor
frizzled family receptor 3
frizzled homolog 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    29127606..29234347 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038435310.1 → XP_038291238.1  frizzled-3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SXF1, A0A8I3PAZ2, A0A8I3PNJ9
    Related
    ENSCAFP00845030790.1, ENSCAFT00845039302.1
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  2. XM_038435309.1 → XP_038291237.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  3. XM_038435306.1 → XP_038291234.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Related
    ENSCAFP00845030870.1, ENSCAFT00845039395.1
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  4. XM_038435307.1 → XP_038291235.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  5. XM_038435308.1 → XP_038291236.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  6. XM_038435312.1 → XP_038291240.1  frizzled-3 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PNJ9
    Conserved Domains (2) summary
    cd15033
    Location:125 → 445
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:1 → 83
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

  7. XM_038435311.1 → XP_038291239.1  frizzled-3 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PNJ9
    Conserved Domains (2) summary
    cd15033
    Location:125 → 445
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:1 → 83
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

  8. XM_038435313.1 → XP_038291241.1  frizzled-3 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PNJ9
    Related
    ENSCAFP00845030729.1, ENSCAFT00845039234.1
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    29087452..29194695 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038510254.1 → XP_038366182.1  frizzled-3 isoform X2

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  2. XM_038510253.1 → XP_038366181.1  frizzled-3 isoform X1

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  3. XM_038510250.1 → XP_038366178.1  frizzled-3 isoform X1

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  4. XM_038510251.1 → XP_038366179.1  frizzled-3 isoform X1

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  5. XM_038510252.1 → XP_038366180.1  frizzled-3 isoform X1

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  6. XM_038510256.1 → XP_038366184.1  frizzled-3 isoform X3

    Conserved Domains (2) summary
    cd15033
    Location:125 → 445
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:1 → 83
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

  7. XM_038510255.1 → XP_038366183.1  frizzled-3 isoform X3

    Conserved Domains (2) summary
    cd15033
    Location:125 → 445
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:1 → 83
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

  8. XM_038510257.1 → XP_038366185.1  frizzled-3 isoform X4

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    28971836..29078759 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038638019.1 → XP_038493947.1  frizzled-3 isoform X2

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  2. XM_038638018.1 → XP_038493946.1  frizzled-3 isoform X1

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  3. XM_038638015.1 → XP_038493943.1  frizzled-3 isoform X1

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  4. XM_038638016.1 → XP_038493944.1  frizzled-3 isoform X1

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  5. XM_038638017.1 → XP_038493945.1  frizzled-3 isoform X1

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  6. XM_038638021.1 → XP_038493949.1  frizzled-3 isoform X3

    Conserved Domains (2) summary
    cd15033
    Location:125 → 445
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:1 → 83
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

  7. XM_038638020.1 → XP_038493948.1  frizzled-3 isoform X3

    Conserved Domains (2) summary
    cd15033
    Location:125 → 445
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:1 → 83
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

  8. XM_038638022.1 → XP_038493950.1  frizzled-3 isoform X4

    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    29137221..29244439 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038573711.1 → XP_038429639.1  frizzled-3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SXF1, A0A8I3PAZ2, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  2. XM_038573710.1 → XP_038429638.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  3. XM_038573707.1 → XP_038429635.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  4. XM_038573708.1 → XP_038429636.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  5. XM_038573709.1 → XP_038429637.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  6. XM_038573713.1 → XP_038429641.1  frizzled-3 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PNJ9
    Conserved Domains (2) summary
    cd15033
    Location:125 → 445
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:1 → 83
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

  7. XM_038573712.1 → XP_038429640.1  frizzled-3 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PNJ9
    Conserved Domains (2) summary
    cd15033
    Location:125 → 445
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:1 → 83
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

  8. XM_038573714.1 → XP_038429642.1  frizzled-3 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    29618932..29725782 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022409710.2 → XP_022265418.1  frizzled-3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SXF1, A0A8I3PAZ2, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  2. XM_038458407.1 → XP_038314335.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  3. XM_543219.7 → XP_543219.2  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  4. XM_014107594.3 → XP_013963069.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  5. XM_022409709.2 → XP_022265417.1  frizzled-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KH62, A0A8C0Z036, A0A8I3PFW0, A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

  6. XM_022409712.2 → XP_022265420.1  frizzled-3 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PNJ9
    Conserved Domains (2) summary
    cd15033
    Location:125 → 445
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:1 → 83
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

  7. XM_022409711.2 → XP_022265419.1  frizzled-3 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PNJ9
    Conserved Domains (2) summary
    cd15033
    Location:125 → 445
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
    cl02447
    Location:1 → 83
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

  8. XM_038458408.1 → XP_038314336.1  frizzled-3 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PNJ9
    Conserved Domains (2) summary
    cd07449
    Location:24 → 150
    CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
    cd15033
    Location:192 → 512
    7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors
Nucleotide Protein
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