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ADRA2A adrenoceptor alpha 2A [ Canis lupus familiaris (dog) ]

Gene ID: 486888, updated on 5-Mar-2024

Summary

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Official Symbol
ADRA2Aprovided by VGNC
Official Full Name
adrenoceptor alpha 2Aprovided by VGNC
Primary source
VGNC:VGNC:52983
See related
Ensembl:ENSCAFG00845029289
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 28
Exon count:
1
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 28 NC_051832.1 (22892378..22895274)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 28 NC_006610.4 (22520055..22522948)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 28 NC_049249.1 (22592510..22595401)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 28 NC_049288.1 (22451483..22454353)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 28 NC_049769.1 (22458352..22461267)

Chromosome 28 - NC_051832.1Genomic Context describing neighboring genes Neighboring gene programmed cell death 4 Neighboring gene BBSome interacting protein 1 Neighboring gene SHOC2 leucine rich repeat scaffold protein Neighboring gene uncharacterized LOC111093044 Neighboring gene 60S ribosomal protein L27-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha2-adrenergic receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in platelet activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of smooth muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of vasoconstriction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-2A adrenergic receptor; LOW QUALITY PROTEIN: alpha-2A adrenergic receptor
Names
adrenergic, alpha-2A-, receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051832.1 Reference ROS_Cfam_1.0

    Range
    22892378..22895274
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038439683.1 → XP_038295611.1  alpha-2A adrenergic receptor

    UniProtKB/TrEMBL
    A0A8I3Q7S8
    Related
    ENSCAFP00845040665.1, ENSCAFT00845051825.1
    Conserved Domains (2) summary
    PHA03247
    Location:244 → 345
    PHA03247; large tegument protein UL36; Provisional
    cd15322
    Location:49 → 472
    7tmA_alpha2A_AR; alpha-2 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049288.1 Alternate UMICH_Zoey_3.1

    Range
    22451483..22454353
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038515661.1 → XP_038371589.1  LOW QUALITY PROTEIN: alpha-2A adrenergic receptor

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049769.1 Alternate UNSW_CanFamBas_1.0

    Range
    22458352..22461267
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038642139.1 → XP_038498067.1  alpha-2A adrenergic receptor

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049249.1 Alternate UU_Cfam_GSD_1.0

    Range
    22592510..22595401
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038577959.1 → XP_038433887.1  alpha-2A adrenergic receptor

    UniProtKB/TrEMBL
    A0A8P0ND24

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006610.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    22520055..22522948
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038460428.1 → XP_038316356.1  alpha-2A adrenergic receptor

    UniProtKB/TrEMBL
    A0A8P0ND24
    Conserved Domains (2) summary
    PHA03307
    Location:245 → 342
    PHA03307; transcriptional regulator ICP4; Provisional
    cd15322
    Location:49 → 471
    7tmA_alpha2A_AR; alpha-2 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
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