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AXIN1 axin 1 [ Canis lupus familiaris (dog) ]

Gene ID: 490099, updated on 5-Mar-2024

Summary

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Official Symbol
AXIN1provided by VGNC
Official Full Name
axin 1provided by VGNC
Primary source
VGNC:VGNC:38324
See related
Ensembl:ENSCAFG00845028817
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
13
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (40497801..40560709)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (41419076..41481969)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (40625599..40688493)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (40186114..40248973)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (40146325..40210047)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene post-GPI attachment to proteins 6 Neighboring gene mitochondrial ribosomal protein L28 Neighboring gene mucin-1-like Neighboring gene protein disulfide isomerase family A member 2 Neighboring gene Rho GDP dissociation inhibitor gamma

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
axin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    40497801..40560709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038669749.1 → XP_038525677.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K8Y3, A0A8C0MYL1, A0A8I3Q4M1
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  2. XM_038669748.1 → XP_038525676.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K8Y3, A0A8C0MYL1, A0A8I3Q4M1
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  3. XM_038669751.1 → XP_038525679.1  axin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0K8X5, A0A8C0S545, A0A8I3Q6C8
    Related
    ENSCAFP00845039966.1, ENSCAFT00845050977.1
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:751 → 828
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  4. XM_038669750.1 → XP_038525678.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K8Y3, A0A8C0MYL1, A0A8I3Q4M1
    Related
    ENSCAFP00845039925.1, ENSCAFT00845050928.1
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    40186114..40248973
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038479673.1 → XP_038335601.1  axin-1 isoform X1

    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  2. XM_038479672.1 → XP_038335600.1  axin-1 isoform X1

    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  3. XM_038479675.1 → XP_038335603.1  axin-1 isoform X2

    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:751 → 828
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  4. XM_038479674.1 → XP_038335602.1  axin-1 isoform X1

    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    40146325..40210047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038605073.1 → XP_038461001.1  axin-1 isoform X1

    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  2. XM_038605072.1 → XP_038461000.1  axin-1 isoform X1

    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  3. XM_038605075.1 → XP_038461003.1  axin-1 isoform X2

    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:751 → 828
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  4. XM_038605074.1 → XP_038461002.1  axin-1 isoform X1

    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    40625599..40688493
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038540948.1 → XP_038396876.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K8Y3, A0A8C0MYL1, A0A8I3Q4M1
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  2. XM_038540947.1 → XP_038396875.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K8Y3, A0A8C0MYL1, A0A8I3Q4M1
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  3. XM_038540950.1 → XP_038396878.1  axin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0K8X5, A0A8C0S545, A0A8I3Q6C8
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:751 → 828
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  4. XM_038540949.1 → XP_038396877.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K8Y3, A0A8C0MYL1, A0A8I3Q4M1
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    41419076..41481969
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022420311.2 → XP_022276019.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K8Y3, A0A8C0MYL1, A0A8I3Q4M1
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  2. XM_038551448.1 → XP_038407376.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K8Y3, A0A8C0MYL1, A0A8I3Q4M1
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  3. XM_038551458.1 → XP_038407386.1  axin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0K8X5, A0A8C0S545, A0A8I3Q6C8
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:751 → 828
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain

  4. XM_038551457.1 → XP_038407385.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K8Y3, A0A8C0MYL1, A0A8I3Q4M1
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:787 → 864
    DIX; DIX domain
    pfam08833
    Location:465 → 494
    Axin_b-cat_bind; Axin beta-catenin binding domain
Nucleotide Protein
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