fosb FBJ murine osteosarcoma viral oncogene homolog B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: fosbprovided by ZNC
Official Full Name: FBJ murine osteosarcoma viral oncogene homolog Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041114-181
See related: Ensembl:ENSDARG00000055751 AllianceGenome:ZFIN:ZDB-GENE-041114-181
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92354
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Orthologous to human FOSB (FosB proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (36768849..36779598)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (36786947..36798590)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phylogenetic and Expression Analysis of Fos Transcription Factors in Zebrafish.
Title: Phylogenetic and Expression Analysis of Fos Transcription Factors in Zebrafish.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein fosB

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001328202.1 → NP_001315131.1 protein fosB

Status: VALIDATED

Source sequence(s)

BX248121, EH434631, EH460635

UniProtKB/TrEMBL

A0A2R8QTZ5, A0A8M1PA30

Related

ENSDARP00000156988.1, ENSDART00000180375.1

Conserved Domains (1) summary

cd14721
Location:208 → 261

bZIP_Fos; Basic leucine zipper (bZIP) domain of the oncogene Fos (Fos): a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007129.7 Reference GRCz11 Primary Assembly

Range

36768849..36779598

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005173641.4 → XP_005173698.1 protein fosB isoform X1

UniProtKB/TrEMBL

A0A8M2BKW7, Q1LXX4

Related

ENSDARP00000114070.1, ENSDART00000133487.3

Conserved Domains (1) summary

cd14721
Location:208 → 261

bZIP_Fos; Basic leucine zipper (bZIP) domain of the oncogene Fos (Fos): a DNA-binding and dimerization domain
XM_005173642.4 → XP_005173699.1 protein fosB isoform X2

UniProtKB/TrEMBL

A0A8M2BL93

Conserved Domains (1) summary

cd14721
Location:208 → 261

bZIP_Fos; Basic leucine zipper (bZIP) domain of the oncogene Fos (Fos): a DNA-binding and dimerization domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001007312.1: Suppressed sequence

Description

NM_001007312.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.