slc6a1b solute carrier family 6 member 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc6a1bprovided by ZNC
Official Full Name: solute carrier family 6 member 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041114-57
See related: Ensembl:ENSDARG00000039647 AllianceGenome:ZFIN:ZDB-GENE-041114-57
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: slc6a1; wu:fj45h10; wu:fq41d04; zgc:103663
Summary: Predicted to enable gamma-aminobutyric acid:sodium symporter activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to act upstream of or within neurotransmitter transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in axon and cell surface. Predicted to be integral component of plasma membrane. Is expressed in basal plate midbrain region and nervous system. Orthologous to human SLC6A1 (solute carrier family 6 member 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (998789..1024483, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (972201..997895, complement)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fj45h10.x1 (e-PCR)
- UniSTS:188586

fj60a08.x1 (e-PCR)
- UniSTS:199646

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables gamma-aminobutyric acid:sodium:chloride symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables gamma-aminobutyric acid:sodium:chloride symporter activity	IEA Inferred from Electronic Annotation more info
enables symporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in amino acid transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within neurotransmitter transport	IEA Inferred from Electronic Annotation more info
involved_in sodium ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in axon	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cell surface	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sodium- and chloride-dependent GABA transporter 1b

Names: gat-1; solute carrier family 6 (neurotransmitter transporter), member 1b; solute carrier family 6 (neurotransmitter transporter, GABA), member 1; solute carrier family 6 (neurotransmitter transporter, GABA), member 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.