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SHC4 SHC adaptor protein 4 [ Bos taurus (cattle) ]

Gene ID: 524734, updated on 11-Apr-2024

Summary

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Official Symbol
SHC4provided by VGNC
Official Full Name
SHC adaptor protein 4provided by VGNC
Primary source
VGNC:VGNC:106925
See related
BGD:BT29578; Ensembl:ENSBTAG00000022583
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (61243632..61420825)

Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene COP9 signalosome subunit 2 Neighboring gene SECIS binding protein 2 like Neighboring gene hypoxanthine phosphoribosyltransferase 1-like pseudogene Neighboring gene EP300 interacting inhibitor of differentiation 1 Neighboring gene centrosomal protein 152 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene endogenous retrovirus group K member 6 Env polyprotein-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SHC-transforming protein 4
Names
SHC (Src homology 2 domain containing) family, member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205912.1 → NP_001192841.1  SHC-transforming protein 4

    See identical proteins and their annotated locations for NP_001192841.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000010
    UniProtKB/TrEMBL
    E1BCR0
    Related
    ENSBTAP00000015489.6, ENSBTAT00000015489.7
    Conserved Domains (2) summary
    cd09925
    Location:518 → 618
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:176 → 347
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    61243632..61420825
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059890432.1 → XP_059746415.1  SHC-transforming protein 4 isoform X1

    UniProtKB/TrEMBL
    E1BCR0

  2. XM_005211817.5 → XP_005211874.1  SHC-transforming protein 4 isoform X2

    Conserved Domains (2) summary
    cd09925
    Location:517 → 617
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:176 → 347
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  3. XM_024997566.2 → XP_024853334.1  SHC-transforming protein 4 isoform X3

    UniProtKB/TrEMBL
    G3N270
    Conserved Domains (3) summary
    cd09925
    Location:458 → 558
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:176 → 347
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain
    cl26464
    Location:44 → 175
    Atrophin-1; Atrophin-1 family

RNA

  1. XR_009496037.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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