akap1b A kinase (PRKA) anchor protein 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: akap1bprovided by ZNC
Official Full Name: A kinase (PRKA) anchor protein 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6844
See related: Ensembl:ENSDARG00000006062 AllianceGenome:ZFIN:ZDB-GENE-030131-6844
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: akap1; fa08b04; wu:fa08b04
Summary: Predicted to enable protein kinase A regulatory subunit binding activity. Predicted to be integral component of membrane. Predicted to be active in membrane and mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; midbrain; musculature system; and segmental plate. Orthologous to human AKAP1 (A-kinase anchoring protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (30840393..30857350, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (30957536..30976609, complement)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables protein kinase A regulatory subunit binding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: A kinase (PRKA) anchor protein 1b; A-kinase anchor protein 1, mitochondrial

Names: A kinase (PRKA) anchor protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001098179.2 → NP_001091649.2 A kinase (PRKA) anchor protein 1b

Status: VALIDATED

Source sequence(s)

BX000438

UniProtKB/TrEMBL

A0A8M6Z0N0, F1RBY1, F6NHG9

Related

ENSDARP00000115383.1, ENSDART00000138988.3

Conserved Domains (3) summary

smart00333
Location:694 → 751

TUDOR; Tudor domain

cd00105
Location:548 → 608

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

pfam00567
Location:641 → 765

TUDOR; Tudor domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007126.7 Reference GRCz11 Primary Assembly

Range

30840393..30857350 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017350962.2 → XP_017206451.1 A-kinase anchor protein 1, mitochondrial isoform X1

UniProtKB/TrEMBL

A0A8M6Z0N0, F1RBY1, F6NHG9

Conserved Domains (3) summary

smart00333
Location:694 → 751

TUDOR; Tudor domain

cd00105
Location:548 → 608

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

pfam00567
Location:641 → 765

TUDOR; Tudor domain