g3bp2a G3BP stress granule assembly factor 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: g3bp2aprovided by ZNC
Official Full Name: G3BP stress granule assembly factor 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070112-1972
See related: Ensembl:ENSDARG00000014790 AllianceGenome:ZFIN:ZDB-GENE-070112-1972
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: g3bp2; fb43h08; fe25b02; wu:fb43h08; wu:fc13c01; wu:fe25b02; zgc:158370
Summary: Predicted to enable mRNA binding activity. Predicted to act upstream of or within innate immune response and stress granule assembly. Predicted to be located in cytoplasmic stress granule. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytosol. Orthologous to human G3BP2 (G3BP stress granule assembly factor 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (26443751..26465429)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (25751272..25771715)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb43h08 (e-PCR)
- UniSTS:187206

fc13c01.x1 (e-PCR)
- UniSTS:192619

fc13c01.x1 (e-PCR)
- UniSTS:192620

fe25b02.x1 (e-PCR)
- UniSTS:196329

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in intracellular organelle	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ras GTPase-activating protein-binding protein 2

Names: GTPase activating protein (SH3 domain) binding protein 2; Ras-GTPase activating protein SH3 domain-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080563.1 → NP_001074032.1 ras GTPase-activating protein-binding protein 2

See identical proteins and their annotated locations for NP_001074032.1

Status: PROVISIONAL

Source sequence(s)

BC129213

UniProtKB/TrEMBL

A0A8M1NCU4, A1L1U3

Related

ENSDARP00000046375.7, ENSDART00000046376.9

Conserved Domains (2) summary

cd00780
Location:7 → 135

NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...

cl17169
Location:348 → 430

RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007112.7 Reference GRCz11 Primary Assembly

Range

26443751..26465429

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021474934.1 → XP_021330609.1 ras GTPase-activating protein-binding protein 2 isoform X1

UniProtKB/TrEMBL

A0A8M1NCU4, A1L1U3

Conserved Domains (2) summary

cd00780
Location:7 → 135

NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...

cl17169
Location:348 → 430

RRM_SF; RNA recognition motif (RRM) superfamily