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nckap1 NCK-associated protein 1 [ Danio rerio (zebrafish) ]

Gene ID: 561894, updated on 11-Apr-2024

Summary

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Official Symbol
nckap1provided by ZNC
Official Full Name
NCK-associated protein 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4426
See related
Ensembl:ENSDARG00000060853 AllianceGenome:ZFIN:ZDB-GENE-030131-4426
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fd05c01; si:dkey-234n3.1
Summary
Acts upstream of or within heart development and neuron projection morphogenesis. Predicted to be located in lamellipodium membrane. Predicted to be integral component of membrane. Orthologous to human NCKAP1 (NCK associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
31
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (44722205..44825419)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (44921239..45024467)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 1A, calmodulin-dependent Neighboring gene uncharacterized LOC103911689 Neighboring gene dual specificity phosphatase 19a Neighboring gene frizzled related protein Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within heart development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within neuron projection morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in lamellipodium membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
nck-associated protein 1
Names
NAP 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001137665.1 → NP_001131137.1  nck-associated protein 1

    Status: PROVISIONAL

    Source sequence(s)
    BX548025, CR513785
    UniProtKB/TrEMBL
    A0A2U3TVM3, A0A8M1NLZ3
    Related
    ENSDARP00000080611.6, ENSDART00000086176.7
    Conserved Domains (1) summary
    pfam09735
    Location:13 → 1118
    Nckap1; Membrane-associated apoptosis protein

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    44722205..44825419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005167921.4 → XP_005167978.1  nck-associated protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A2R8QPW3, A0A8M2BFC9
    Related
    ENSDARP00000156716.1, ENSDART00000190578.1
    Conserved Domains (1) summary
    pfam09735
    Location:13 → 1128
    Nckap1; Membrane-associated apoptosis protein

  2. XM_005167922.4 → XP_005167979.1  nck-associated protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M2BFE2
    Conserved Domains (1) summary
    pfam09735
    Location:13 → 1126
    Nckap1; Membrane-associated apoptosis protein

  3. XM_005167923.4 → XP_005167980.1  nck-associated protein 1 isoform X3

    See identical proteins and their annotated locations for XP_005167980.1

    UniProtKB/Swiss-Prot
    B0S6R0, B0S6R1
    Related
    ENSDARP00000116328.1, ENSDART00000132696.2
    Conserved Domains (1) summary
    pfam09735
    Location:13 → 1122
    Nckap1; Membrane-associated apoptosis protein

  4. XM_005167924.4 → XP_005167981.1  nck-associated protein 1 isoform X4

    UniProtKB/Swiss-Prot
    B0S6R1
    Conserved Domains (1) summary
    pfam09735
    Location:13 → 1120
    Nckap1; Membrane-associated apoptosis protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B0S6R1.1 GenPept UniProtKB/Swiss-Prot:B0S6R1

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