TENM2 teneurin transmembrane protein 2 [Homo sapiens (human)] - Gene

Summary

Official Symbol: TENM2provided by HGNC
Official Full Name: teneurin transmembrane protein 2provided by HGNC
Primary source: HGNC:HGNC:29943
See related: Ensembl:ENSG00000145934 MIM:610119; AllianceGenome:HGNC:29943
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: ODZ2; TEN2; TNM2; ten-2; TEN-M2
Summary: Enables cell adhesion molecule binding activity and signaling receptor binding activity. Involved in several processes, including calcium-mediated signaling using intracellular calcium source; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and retrograde trans-synaptic signaling by trans-synaptic protein complex. Located in cell-cell junction and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in heart (RPKM 7.7), brain (RPKM 2.7) and 6 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 5q34

Exon count:: 39

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	5	NC_000005.10 (166979029..168264157)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	5	NC_060929.1 (167513669..168798988)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	5	NC_000005.9 (166406034..167691162)

Chromosome 5 - NC_000005.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These findings reveal a novel mechanism of axonal pathfinding, whereby latrophilin-1 and Lasso mediate both short-range interaction that supports synaptogenesis, and long-range signaling that induces axonal attraction.
Title: Proteolytically released Lasso/teneurin-2 induces axonal attraction by interacting with latrophilin-1 on axonal growth cones.
TENM2 knockdown induces both UCP1 mRNA and protein expression upon adipogenic differentiation without affecting mitochondrial mass.
Title: Teneurin-2 (TENM2) deficiency induces UCP1 expression in differentiating human fat cells.
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Gene rearrangements of ODZ2 is associated with mucosa-associated lymphoid tissue lymphoma.
Title: Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3.
intracellular domain of teneurin-2 has a nuclear function and role in repressing zic-1-mediated transcription
Title: The intracellular domain of teneurin-2 has a nuclear function and represses zic-1-mediated transcription.

Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association of serum uric acid concentration: replication of sequence variants in an island population of the Adriatic coast of Croatia. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association studies and heritability estimates of body mass index related phenotypes in bangladeshi adults. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association study of periodontal pathogen colonization. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. EBI GWAS Catalog EBI GWAS CatalogPubMed
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

SHGC-78928 (e-PCR)
- UniSTS:95745

SHGC-68636 (e-PCR)
- UniSTS:95492

SHGC-23892 (e-PCR)
- UniSTS:70668

D5S496 (e-PCR), detects polymorphism
- UniSTS:39440

RH122050 (e-PCR)
- UniSTS:134686

ODZ2_3320 (e-PCR)
- UniSTS:462379

WI-22532 (e-PCR)
- UniSTS:76079

A004A45 (e-PCR)
- UniSTS:4914

SHGC-107168 (e-PCR)
- UniSTS:170295

D5S619 (e-PCR), detects polymorphism
- UniSTS:37176

SHGC-13056 (e-PCR)
- UniSTS:69946

SHGC-154041 (e-PCR)
- UniSTS:184126

G18151 (e-PCR)
- UniSTS:68680

G43625 (e-PCR)
- UniSTS:95056

D5S805 (e-PCR)
- UniSTS:80722

SHGC-110807 (e-PCR)
- UniSTS:168027

G19199 (e-PCR)
- UniSTS:46427

SHGC-145647 (e-PCR)
- UniSTS:174704

G28629 (e-PCR)
- UniSTS:59001

WI-3815 (e-PCR)
- UniSTS:15994

D5S1458 (e-PCR), detects polymorphism
- UniSTS:9099

CHLC.GCT10G10 (e-PCR)
- UniSTS:37515

SHGC-13752 (e-PCR)
- UniSTS:44688

D5S1471 (e-PCR), detects polymorphism
- UniSTS:62868

SHGC-111408 (e-PCR)
- UniSTS:168356

D5S1888 (e-PCR)
- UniSTS:60068

D5S496 (e-PCR), detects polymorphism
- UniSTS:2476

bac5967T (e-PCR)
- UniSTS:181688

RH78971 (e-PCR)
- UniSTS:9147

bac5977T (e-PCR)
- UniSTS:181691

bac5992T (e-PCR)
- UniSTS:181693

D5S2458 (e-PCR)
- UniSTS:76484

WI-22163 (e-PCR)
- UniSTS:61638

SHGC-144555 (e-PCR)
- UniSTS:174285

SHGC-84519 (e-PCR)
- UniSTS:102863

G16914 (e-PCR)
- UniSTS:60111

SHGC-147036 (e-PCR)
- UniSTS:175570

L18086 (e-PCR)
- UniSTS:22244

RH77908 (e-PCR)
- UniSTS:4079

SHGC-132122 (e-PCR)
- UniSTS:184047

RH11035 (e-PCR)
- UniSTS:48630

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables cell adhesion molecule binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein heterodimerization activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein heterodimerization activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein homodimerization activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein homodimerization activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in cell-cell adhesion	ISS Inferred from Sequence or Structural Similarity more info
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info
involved_in neuron development	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of filopodium assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in retrograde trans-synaptic signaling by trans-synaptic protein complex	EXP Inferred from Experiment more info	PubMed
involved_in retrograde trans-synaptic signaling by trans-synaptic protein complex	IDA Inferred from Direct Assay more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	ISS Inferred from Sequence or Structural Similarity more info
located_in PML body	ISS Inferred from Sequence or Structural Similarity more info
located_in cell junction	ISS Inferred from Sequence or Structural Similarity more info
located_in dendrite	ISS Inferred from Sequence or Structural Similarity more info
located_in dendritic spine	ISS Inferred from Sequence or Structural Similarity more info
located_in endoplasmic reticulum	ISS Inferred from Sequence or Structural Similarity more info
located_in filopodium	ISS Inferred from Sequence or Structural Similarity more info
located_in growth cone	ISS Inferred from Sequence or Structural Similarity more info
is_active_in neuron projection	IBA Inferred from Biological aspect of Ancestor more info
located_in neuron projection	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in postsynaptic membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in synapse	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: teneurin-2

Names: neurestin alpha; odd Oz/ten-m homolog 2; odz, odd Oz/ten-m homolog 2; protein Odd Oz/ten-m homolog 2; tenascin-M2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080428.3 → NP_001073897.2 teneurin-2 isoform 2

Status: VALIDATED

Description

Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region and has multiple difference in the central coding region compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus compared to isoform 1.

Source sequence(s)

AB032953, AC093304, AK056053, AL137500, BF950845, BQ774782, BX648178, CR936703

Consensus CDS

CCDS83040.1

UniProtKB/TrEMBL

A0A8Q3SIB5, F8VNQ3

Related

ENSP00000427874.1, ENST00000520394.5

Conserved Domains (12) summary

COG3209
Location:1450 → 2243

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd00054
Location:439 → 468

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:1046 → 1095

NHL; NHL repeat [structural motif]

TIGR03696
Location:2152 → 2228

Rhs_assc_core; RHS repeat-associated core domain

pfam01500
Location:502 → 650

Keratin_B2; Keratin, high sulfur B2 protein

pfam05593
Location:1443 → 1481

RHS_repeat; RHS Repeat

pfam06484
Location:16 → 183

Ten_N; Teneurin Intracellular Region

pfam07974
Location:348 → 370

EGF_2; EGF-like domain

pfam13715
Location:700 → 784

CarbopepD_reg_2; CarboxypepD_reg-like domain

pfam15636
Location:2453 → 2528

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

cl18310
Location:1008 → 1331

NHL; NHL repeat unit of beta-propeller proteins

cl19567
Location:523 → 564

DSL; Delta serrate ligand
NM_001122679.2 → NP_001116151.1 teneurin-2 isoform 1

See identical proteins and their annotated locations for NP_001116151.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

Source sequence(s)

AC008464, AC008601, AC008607, AC008637, AC008642, AC008705, AC011369, AC026689, AC093304

UniProtKB/TrEMBL

A0A8Q3SIB5

Conserved Domains (10) summary

COG3209
Location:1946 → 2432

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd00054
Location:798 → 831

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:1231 → 1270

NHL; NHL repeat [structural motif]

TIGR03696
Location:2382 → 2458

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1231 → 1561

NHL; NHL repeat unit of beta-propeller proteins

pfam05593
Location:1673 → 1709

RHS_repeat; RHS Repeat

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2681 → 2758

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

pfam19232
Location:575 → 734

DUF5885; Family of unknown function (DUF5885)

cl19567
Location:755 → 796

DSL; Delta serrate ligand
NM_001368145.1 → NP_001355074.1 teneurin-2 isoform 3

Status: VALIDATED

Source sequence(s)

AC008464, AC008634, AC008637, AC008705, AC011369, AC026689, AC093304

UniProtKB/TrEMBL

A0A8Q3SIB5
NM_001368146.1 → NP_001355075.1 teneurin-2 isoform 4

Status: VALIDATED

Source sequence(s)

AC008464, AC008634, AC008637, AC008705, AC011369, AC026689, AC093304

Consensus CDS

CCDS93819.1

UniProtKB/TrEMBL

A0A8Q3SI97, A0A8Q3SIB5

Related

ENSP00000512239.1, ENST00000695886.1
NM_001395460.1 → NP_001382389.1 teneurin-2 isoform 5

Status: VALIDATED

Source sequence(s)

AC008464, AC008601, AC008607, AC008637, AC008642, AC008705, AC011369, AC026689, AC026729, AC093304

Consensus CDS

CCDS93818.1

UniProtKB/Swiss-Prot

Q9NT68, Q9ULU2

UniProtKB/TrEMBL

A0A8Q3SIB5

Related

ENSP00000429430.1, ENST00000518659.6

Conserved Domains (8) summary

COG3209
Location:1955 → 2441

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd05819
Location:1240 → 1279

NHL; NHL repeat [structural motif]

TIGR03696
Location:2391 → 2467

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1240 → 1570

NHL; NHL repeat unit of beta-propeller proteins

pfam05593
Location:1682 → 1718

RHS_repeat; RHS Repeat

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2690 → 2767

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

NF033759
Location:570 → 885

exchanger_TraA; outer membrane exchange protein TraA

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000005.10 Reference GRCh38.p14 Primary Assembly

Range

166979029..168264157

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_047417418.1 → XP_047273374.1 teneurin-2 isoform X3

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_017009661.2 → XP_016865150.1 teneurin-2 isoform X1

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_005265950.3 → XP_005266007.1 teneurin-2 isoform X2

See identical proteins and their annotated locations for XP_005266007.1

UniProtKB/TrEMBL

A0A8Q3SIB5

Conserved Domains (10) summary

COG3209
Location:1946 → 2432

RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]

cd00054
Location:798 → 831

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:1231 → 1270

NHL; NHL repeat [structural motif]

TIGR03696
Location:2382 → 2458

Rhs_assc_core; RHS repeat-associated core domain

cl18310
Location:1231 → 1561

NHL; NHL repeat unit of beta-propeller proteins

pfam05593
Location:1673 → 1709

RHS_repeat; RHS Repeat

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam15636
Location:2681 → 2758

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

pfam19232
Location:575 → 734

DUF5885; Family of unknown function (DUF5885)

cl19567
Location:755 → 796

DSL; Delta serrate ligand
XM_011534604.3 → XP_011532906.1 teneurin-2 isoform X5

UniProtKB/TrEMBL

A0A8Q3SIB5

Conserved Domains (11) summary

COG3209
Location:1618 → 2411

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd00054
Location:671 → 700

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:1169 → 1208

NHL; NHL repeat [structural motif]

TIGR03696
Location:2320 → 2396

Rhs_assc_core; RHS repeat-associated core domain

pfam01500
Location:640 → 811

Keratin_B2; Keratin, high sulfur B2 protein

pfam05593
Location:1611 → 1649

RHS_repeat; RHS Repeat

pfam06484
Location:10 → 374

Ten_N; Teneurin Intracellular Region

pfam07974
Location:576 → 602

EGF_2; EGF-like domain

pfam13715
Location:861 → 945

CarbopepD_reg_2; CarboxypepD_reg-like domain

pfam15636
Location:2621 → 2696

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

cl18310
Location:1169 → 1499

NHL; NHL repeat unit of beta-propeller proteins
XM_047417420.1 → XP_047273376.1 teneurin-2 isoform X8

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_017009662.2 → XP_016865151.1 teneurin-2 isoform X4

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417419.1 → XP_047273375.1 teneurin-2 isoform X7

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_017009665.2 → XP_016865154.1 teneurin-2 isoform X16

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417427.1 → XP_047273383.1 teneurin-2 isoform X17

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_017009669.2 → XP_016865158.1 teneurin-2 isoform X20

UniProtKB/TrEMBL

A0A8Q3SIA3, A0A8Q3SIB5
XM_017009663.3 → XP_016865152.1 teneurin-2 isoform X6

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417421.1 → XP_047273377.1 teneurin-2 isoform X9

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417422.1 → XP_047273378.1 teneurin-2 isoform X10

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417423.1 → XP_047273379.1 teneurin-2 isoform X11

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_017009664.2 → XP_016865153.1 teneurin-2 isoform X12

UniProtKB/TrEMBL

A0A8Q3SIB5, G3V106

Related

ENSP00000428964.1, ENST00000519204.5

Conserved Domains (12) summary

COG3209
Location:1568 → 2361

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd00054
Location:550 → 579

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:1119 → 1158

NHL; NHL repeat [structural motif]

TIGR03696
Location:2270 → 2346

Rhs_assc_core; RHS repeat-associated core domain

pfam01500
Location:613 → 761

Keratin_B2; Keratin, high sulfur B2 protein

pfam05593
Location:1561 → 1599

RHS_repeat; RHS Repeat

pfam06484
Location:44 → 253

Ten_N; Teneurin Intracellular Region

pfam07974
Location:459 → 481

EGF_2; EGF-like domain

pfam13715
Location:811 → 895

CarbopepD_reg_2; CarboxypepD_reg-like domain

pfam15636
Location:2571 → 2646

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

cl18310
Location:1119 → 1449

NHL; NHL repeat unit of beta-propeller proteins

cl19567
Location:634 → 675

DSL; Delta serrate ligand
XM_047417424.1 → XP_047273380.1 teneurin-2 isoform X13

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417425.1 → XP_047273381.1 teneurin-2 isoform X14

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417426.1 → XP_047273382.1 teneurin-2 isoform X15

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417432.1 → XP_047273388.1 teneurin-2 isoform X21

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417430.1 → XP_047273386.1 teneurin-2 isoform X19

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_017009668.2 → XP_016865157.1 teneurin-2 isoform X20

UniProtKB/TrEMBL

A0A8Q3SIA3, A0A8Q3SIB5

Related

ENSP00000512289.1, ENST00000695961.1
XM_047417431.1 → XP_047273387.1 teneurin-2 isoform X19

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417428.1 → XP_047273384.1 teneurin-2 isoform X18

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417429.1 → XP_047273385.1 teneurin-2 isoform X19

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417433.1 → XP_047273389.1 teneurin-2 isoform X22

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_005265952.3 → XP_005266009.1 teneurin-2 isoform X23

UniProtKB/TrEMBL

A0A8Q3SIB5

Related

ENSP00000512290.1, ENST00000695962.1

Conserved Domains (11) summary

COG3209
Location:1293 → 2086

RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]

cd00054
Location:275 → 304

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd05819
Location:844 → 883

NHL; NHL repeat [structural motif]

TIGR03696
Location:1995 → 2071

Rhs_assc_core; RHS repeat-associated core domain

pfam01500
Location:338 → 486

Keratin_B2; Keratin, high sulfur B2 protein

pfam05593
Location:1286 → 1324

RHS_repeat; RHS Repeat

pfam07974
Location:184 → 206

EGF_2; EGF-like domain

pfam13715
Location:536 → 620

CarbopepD_reg_2; CarboxypepD_reg-like domain

pfam15636
Location:2296 → 2371

Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

cl18310
Location:844 → 1174

NHL; NHL repeat unit of beta-propeller proteins

cl19567
Location:359 → 400

DSL; Delta serrate ligand
XM_047417434.1 → XP_047273390.1 teneurin-2 isoform X24

UniProtKB/TrEMBL

A0A8Q3SIB5
XM_047417435.1 → XP_047273391.1 teneurin-2 isoform X25

UniProtKB/TrEMBL

A0A8Q3SIB5