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PRDM15 PR/SET domain 15 [ Homo sapiens (human) ]

Gene ID: 63977, updated on 3-Apr-2024

Summary

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Official Symbol
PRDM15provided by HGNC
Official Full Name
PR/SET domain 15provided by HGNC
Primary source
HGNC:HGNC:13999
See related
Ensembl:ENSG00000141956 MIM:617692; AllianceGenome:HGNC:13999
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PFM15; ZNF298; C21orf83
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II; regulation of signal transduction; and regulation of stem cell division. Located in nuclear body. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in lymph node (RPKM 2.4), appendix (RPKM 1.2) and 25 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
21q22.3
Exon count:
37
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (41798225..41879344, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (40188592..40269664, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (43218385..43299453, complement)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:43173001-43173792 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:43180486-43181120 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:43181121-43181755 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:43181756-43182390 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr21:43182391-43183024 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:43183726-43184325 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:43184326-43184924 Neighboring gene microRNA 6814 Neighboring gene receptor interacting serine/threonine kinase 4 Neighboring gene uncharacterized LOC102724800 Neighboring gene Sharpr-MPRA regulatory region 172 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:43192149-43192696 Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:43216480-43216980 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18485 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr21:43241376-43242575 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18486 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18487 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:43256373-43257080 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr21:43274198-43275397 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18488 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18489 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18490 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18491 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18492 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13333 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18493 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:43318691-43319691 Neighboring gene C2 calcium dependent domain containing 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18494 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18495 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18496 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:43364315-43364815 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:43370715-43371220 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:43373099-43373873 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18497 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:43378985-43379952 Neighboring gene small nucleolar RNA, H/ACA box 91 Neighboring gene NANOG hESC enhancer GRCh37_chr21:43388567-43389068 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:43415728-43415930 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13335 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13336 Neighboring gene zinc finger and BTB domain containing 21 Neighboring gene ZNF295 antisense RNA 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Proof-of-Concept Method to Study Uncharacterized Methyltransferases Using PRDM15. Zhao LN, et al. Int J Mol Sci, 2023 Jan 10. PMID 36674842, Free PMC Article
  2. Mutations in PRDM15 Are a Novel Cause of Galloway-Mowat Syndrome. Mann N, et al. J Am Soc Nephrol, 2021 Mar. PMID 33593823, Free PMC Article
  3. PRDM15 Is Associated with Risk of Chronic Obstructive Pulmonary Disease in a Rural Population in Chile. Hosgood Iii HD, et al. Respiration, 2020. PMID 32222710
  4. Identification of a novel zinc finger protein gene (ZNF298) in the GAP2 of human chromosome 21q. Shibuya K, et al. Biochem Biophys Res Commun, 2005 Jul 1. PMID 15904895
  5. PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling. Mzoughi S, et al. Nat Genet, 2017 Sep. PMID 28740264

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression.
    Title: The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression.
  2. Proof-of-Concept Method to Study Uncharacterized Methyltransferases Using PRDM15.
    Title: Proof-of-Concept Method to Study Uncharacterized Methyltransferases Using PRDM15.
  3. Mutations in PRDM15 Are a Novel Cause of Galloway-Mowat Syndrome.
    Title: Mutations in PRDM15 Are a Novel Cause of Galloway-Mowat Syndrome.
  4. PRDM15 Is Associated with Risk of Chronic Obstructive Pulmonary Disease in a Rural Population in Chile.
    Title: PRDM15 Is Associated with Risk of Chronic Obstructive Pulmonary Disease in a Rural Population in Chile.
  5. PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly.
    Title: PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly.
  6. Findings indicate that PR domain containing 15 protein (PRDM15) is important in both mouse and human induced pluripotent stem cells (iPSCs) reprogramming.
    Title: PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genetic association with overall survival of taxane-treated lung cancer patients - A genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study.
EBI GWAS Catalog
Genome-wide association study of tanning phenotype in a population of European ancestry.
EBI GWAS Catalog
Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • AP001619.2

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables promoter-specific chromatin binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of MAPK cascade ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of canonical Wnt signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of stem cell division ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nuclear body IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
PR domain zinc finger protein 15
Names
PR domain 15
PR domain containing 15
zinc finger protein 298

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040424.3 → NP_001035514.2  PR domain zinc finger protein 15 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks seven alternate in-frame exons and differs in the 3' UTR, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AB051812, AP002955, HY066601
    Consensus CDS
    CCDS42932.2
    UniProtKB/TrEMBL
    E7ER26, E9PL97, Q6NXF8
    Related
    ENSP00000381556.2, ENST00000398548.6
    Conserved Domains (6) summary
    COG5048
    Location:363 → 825
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:692 → 712
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:628 → 649
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam16031
    Location:227 → 310
    TonB_N; TonB N-terminal region
    pfam18445
    Location:12 → 37
    zf_PR_Knuckle; PR zinc knuckle motif
    cd19199
    Location:41 → 166
    PR-SET_PRDM15; PR-SET domain found in PR domain zinc finger protein 15 (PRDM15) and similar proteins

  2. NM_001282934.2 → NP_001269863.2  PR domain zinc finger protein 15 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks seven alternate in-frame exons, contains an alternate in-frame exon, and differs in the 3' UTR, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
    Source sequence(s)
    AP001619, AP002955, BC032305, HY066601
    Consensus CDS
    CCDS63370.2
    UniProtKB/TrEMBL
    Q6NXF8
    Related
    ENSP00000408592.2, ENST00000422911.6
    Conserved Domains (7) summary
    COG5048
    Location:676 → 845
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:712 → 732
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:648 → 669
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:372 → 394
    zf-C2H2; Zinc finger, C2H2 type
    pfam16031
    Location:227 → 310
    TonB_N; TonB N-terminal region
    pfam18445
    Location:12 → 37
    zf_PR_Knuckle; PR zinc knuckle motif
    cd19199
    Location:41 → 166
    PR-SET_PRDM15; PR-SET domain found in PR domain zinc finger protein 15 (PRDM15) and similar proteins

  3. NM_022115.7 → NP_071398.5  PR domain zinc finger protein 15 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AB126081, AP001618, AP001619, AP002955
    Consensus CDS
    CCDS13676.2
    UniProtKB/TrEMBL
    Q6NXF8
    Related
    ENSP00000269844.4, ENST00000269844.5
    Conserved Domains (6) summary
    COG5048
    Location:429 → 891
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:758 → 778
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:694 → 715
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam18445
    Location:12 → 37
    zf_PR_Knuckle; PR zinc knuckle motif
    cd19199
    Location:107 → 232
    PR-SET_PRDM15; PR-SET domain found in PR domain zinc finger protein 15 (PRDM15) and similar proteins
    NF033909
    Location:293 → 400
    opacity_OapA; opacity-associated protein OapA

RNA

  1. NR_104257.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) contains multiple differences in the internal exons and differs in the 3' terminal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AB051814, AB126081, AP002955
    Related
    ENST00000449395.6

  2. NR_104258.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) contains multiple differences in the internal exons and differs in the 3' terminal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AB051815, AB126081, AP002955
    Related
    ENST00000441787.5

  3. NR_104260.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) contains multiple differences, including use of an alternate 3' exon structure, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AB126081, AP001618, AP002955, AY063456, BC067102

  4. NR_135464.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) contains multiple differences, including use of an alternate 3' exon structure, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AF276513, AP002955, AY063456, BM544857, BM755202, CA949877, CF135664, CF137278, CF138151, CN400247, EC485279, HY003319, HY146343

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    41798225..41879344 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047440940.1 → XP_047296896.1  PR domain zinc finger protein 15 isoform X8

  2. XM_047440938.1 → XP_047296894.1  PR domain zinc finger protein 15 isoform X5

  3. XM_047440939.1 → XP_047296895.1  PR domain zinc finger protein 15 isoform X7

  4. XM_017028425.2 → XP_016883914.1  PR domain zinc finger protein 15 isoform X6

    UniProtKB/TrEMBL
    E7ER26, E9PL97, Q6NXF8
    Related
    ENSP00000431410.1, ENST00000447016.6
    Conserved Domains (6) summary
    COG5048
    Location:363 → 825
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:692 → 712
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:628 → 649
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam16031
    Location:227 → 310
    TonB_N; TonB N-terminal region
    pfam18445
    Location:12 → 37
    zf_PR_Knuckle; PR zinc knuckle motif
    cd19199
    Location:41 → 166
    PR-SET_PRDM15; PR-SET domain found in PR domain zinc finger protein 15 (PRDM15) and similar proteins

  5. XM_047440937.1 → XP_047296893.1  PR domain zinc finger protein 15 isoform X4

  6. XM_011529675.2 → XP_011527977.1  PR domain zinc finger protein 15 isoform X3

    See identical proteins and their annotated locations for XP_011527977.1

    UniProtKB/TrEMBL
    Q6NXF8
    Conserved Domains (7) summary
    COG5048
    Location:676 → 845
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:712 → 732
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:648 → 669
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:372 → 394
    zf-C2H2; Zinc finger, C2H2 type
    pfam16031
    Location:227 → 310
    TonB_N; TonB N-terminal region
    pfam18445
    Location:12 → 37
    zf_PR_Knuckle; PR zinc knuckle motif
    cd19199
    Location:41 → 166
    PR-SET_PRDM15; PR-SET domain found in PR domain zinc finger protein 15 (PRDM15) and similar proteins

  7. XM_047440935.1 → XP_047296891.1  PR domain zinc finger protein 15 isoform X5

  8. XM_011529674.2 → XP_011527976.2  PR domain zinc finger protein 15 isoform X2

  9. XM_006724040.3 → XP_006724103.2  PR domain zinc finger protein 15 isoform X7

  10. XM_006724039.3 → XP_006724102.2  PR domain zinc finger protein 15 isoform X4

  11. XM_011529683.2 → XP_011527985.2  PR domain zinc finger protein 15 isoform X9

  12. XM_011529678.3 → XP_011527980.1  PR domain zinc finger protein 15 isoform X3

    See identical proteins and their annotated locations for XP_011527980.1

    UniProtKB/TrEMBL
    Q6NXF8
    Conserved Domains (7) summary
    COG5048
    Location:676 → 845
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:712 → 732
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:648 → 669
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:372 → 394
    zf-C2H2; Zinc finger, C2H2 type
    pfam16031
    Location:227 → 310
    TonB_N; TonB N-terminal region
    pfam18445
    Location:12 → 37
    zf_PR_Knuckle; PR zinc knuckle motif
    cd19199
    Location:41 → 166
    PR-SET_PRDM15; PR-SET domain found in PR domain zinc finger protein 15 (PRDM15) and similar proteins

  13. XM_011529681.4 → XP_011527983.1  PR domain zinc finger protein 15 isoform X1

    See identical proteins and their annotated locations for XP_011527983.1

    UniProtKB/TrEMBL
    Q6NXF8
    Conserved Domains (7) summary
    smart00317
    Location:53 → 169
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    COG5048
    Location:367 → 820
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:716 → 736
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:652 → 673
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:376 → 398
    zf-C2H2; Zinc finger, C2H2 type
    pfam06217
    Location:219 → 284
    GAGA_bind; GAGA binding protein-like family
    pfam13465
    Location:728 → 753
    zf-H2C2_2; Zinc-finger double domain

  14. XM_011529676.3 → XP_011527978.1  PR domain zinc finger protein 15 isoform X3

    See identical proteins and their annotated locations for XP_011527978.1

    UniProtKB/TrEMBL
    Q6NXF8
    Conserved Domains (7) summary
    COG5048
    Location:676 → 845
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:712 → 732
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:648 → 669
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:372 → 394
    zf-C2H2; Zinc finger, C2H2 type
    pfam16031
    Location:227 → 310
    TonB_N; TonB N-terminal region
    pfam18445
    Location:12 → 37
    zf_PR_Knuckle; PR zinc knuckle motif
    cd19199
    Location:41 → 166
    PR-SET_PRDM15; PR-SET domain found in PR domain zinc finger protein 15 (PRDM15) and similar proteins

  15. XM_047440936.1 → XP_047296892.1  PR domain zinc finger protein 15 isoform X6

    UniProtKB/TrEMBL
    E7ER26, E9PL97

  16. XM_011529677.3 → XP_011527979.1  PR domain zinc finger protein 15 isoform X3

    See identical proteins and their annotated locations for XP_011527979.1

    UniProtKB/TrEMBL
    Q6NXF8
    Conserved Domains (7) summary
    COG5048
    Location:676 → 845
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:712 → 732
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:648 → 669
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:372 → 394
    zf-C2H2; Zinc finger, C2H2 type
    pfam16031
    Location:227 → 310
    TonB_N; TonB N-terminal region
    pfam18445
    Location:12 → 37
    zf_PR_Knuckle; PR zinc knuckle motif
    cd19199
    Location:41 → 166
    PR-SET_PRDM15; PR-SET domain found in PR domain zinc finger protein 15 (PRDM15) and similar proteins

  17. XM_011529679.3 → XP_011527981.1  PR domain zinc finger protein 15 isoform X3

    See identical proteins and their annotated locations for XP_011527981.1

    UniProtKB/TrEMBL
    Q6NXF8
    Conserved Domains (7) summary
    COG5048
    Location:676 → 845
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:712 → 732
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:648 → 669
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:372 → 394
    zf-C2H2; Zinc finger, C2H2 type
    pfam16031
    Location:227 → 310
    TonB_N; TonB N-terminal region
    pfam18445
    Location:12 → 37
    zf_PR_Knuckle; PR zinc knuckle motif
    cd19199
    Location:41 → 166
    PR-SET_PRDM15; PR-SET domain found in PR domain zinc finger protein 15 (PRDM15) and similar proteins

RNA

  1. XR_007067792.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    40188592..40269664 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054324753.1 → XP_054180728.1  PR domain zinc finger protein 15 isoform X8

  2. XM_054324751.1 → XP_054180726.1  PR domain zinc finger protein 15 isoform X5

  3. XM_054324752.1 → XP_054180727.1  PR domain zinc finger protein 15 isoform X7

  4. XM_054324747.1 → XP_054180722.1  PR domain zinc finger protein 15 isoform X6

  5. XM_054324750.1 → XP_054180725.1  PR domain zinc finger protein 15 isoform X4

  6. XM_054324740.1 → XP_054180715.1  PR domain zinc finger protein 15 isoform X3

  7. XM_054324746.1 → XP_054180721.1  PR domain zinc finger protein 15 isoform X5

  8. XM_054324739.1 → XP_054180714.1  PR domain zinc finger protein 15 isoform X2

  9. XM_054324749.1 → XP_054180724.1  PR domain zinc finger protein 15 isoform X7

  10. XM_054324745.1 → XP_054180720.1  PR domain zinc finger protein 15 isoform X4

  11. XM_054324754.1 → XP_054180729.1  PR domain zinc finger protein 15 isoform X9

  12. XM_054324743.1 → XP_054180718.1  PR domain zinc finger protein 15 isoform X3

  13. XM_054324738.1 → XP_054180713.1  PR domain zinc finger protein 15 isoform X1

  14. XM_054324742.1 → XP_054180717.1  PR domain zinc finger protein 15 isoform X3

  15. XM_054324748.1 → XP_054180723.1  PR domain zinc finger protein 15 isoform X6

  16. XM_054324741.1 → XP_054180716.1  PR domain zinc finger protein 15 isoform X3

  17. XM_054324744.1 → XP_054180719.1  PR domain zinc finger protein 15 isoform X3

RNA

  1. XR_008485343.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P57071.4 GenPept UniProtKB/Swiss-Prot:P57071

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