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TPTE2P1 TPTE2 pseudogene 1 [ Homo sapiens (human) ]

Gene ID: 646405, updated on 10-Oct-2023

Summary

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Official Symbol
TPTE2P1provided by HGNC
Official Full Name
TPTE2 pseudogene 1provided by HGNC
Primary source
HGNC:HGNC:35196
See related
AllianceGenome:HGNC:35196
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in brain (RPKM 1.4), thyroid (RPKM 0.8) and 11 other tissues See more
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Genomic context

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Location:
13q12.13
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (24928755..24968484, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (24137007..24176744, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (25502893..25542607, complement)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7479 Neighboring gene ankyrin repeat domain 20 family member A10, pseudogene Neighboring gene iroquois homeobox 1 pseudogene 1 Neighboring gene ring finger protein 17 Neighboring gene Sharpr-MPRA regulatory region 11275 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5181 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:25467896-25468814 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7480 Neighboring gene centromere protein J Neighboring gene MED14-independent group 3 enhancer GRCh37_chr13:25484884-25486083 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:25496143-25497044 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:25497045-25497946 Neighboring gene solute carrier family 25 member 15 pseudogene 3 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:25531195-25531774 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:25543733-25544640 Neighboring gene ribosomal protein L34 pseudogene 27 Neighboring gene Sharpr-MPRA regulatory region 15462 Neighboring gene striatin, calmodulin binding protein pseudogene Neighboring gene LSP1 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Long noncoding RNA TPTE2P1 promotes the migration and invasion of hepatocellular carcinoma. Liu J, et al. Eur Rev Med Pharmacol Sci, 2019 May. PMID 31114999
  2. The long noncoding RNA TPTE2P1 promotes the viability of colorectal cancer cells. Dai X, et al. J Cell Biochem, 2019 Apr. PMID 30382596
  3. LncRNA TPTE2P1 promotes the proliferation of thyroid carcinoma by inhibiting miR-520c-3p. Peng L, et al. Panminerva Med, 2020 Mar. PMID 31144790
  4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. Comuzzie AG, et al. PLoS One, 2012. PMID 23251661, Free PMC Article
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LncRNA TPTE2P1 promotes the proliferation of thyroid carcinoma by inhibiting miR-520c-3p.
    Title: LncRNA TPTE2P1 promotes the proliferation of thyroid carcinoma by inhibiting miR-520c-3p.
  2. Long noncoding RNA TPTE2P1 promotes the migration and invasion of hepatocellular carcinoma.
    Title: Long noncoding RNA TPTE2P1 promotes the migration and invasion of hepatocellular carcinoma.
  3. TPTE2P1 is upregulated in colorectal cancer and plays essential roles in the regulation of cell viability in vitro and tumor formation in vivo.
    Title: The long noncoding RNA TPTE2P1 promotes the viability of colorectal cancer cells.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
EBI GWAS Catalog

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_026730.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL354798

  2. NR_178209.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL354798

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    24928755..24968484 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    24137007..24176744 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001126062.1: Suppressed sequence

    Description
    NM_001126062.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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