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MIR566 microRNA 566 [ Homo sapiens (human) ]

Gene ID: 693151, discontinued on 14-Mar-2018
  • This record was discontinued.

Summary

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Official Symbol
MIR566provided by HGNC
Official Full Name
microRNA 566provided by HGNC
Primary source
HGNC:HGNC:32822
See related
miRBase:MI0003572
Gene type
ncRNA
RefSeq status
WITHDRAWN
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MIRN566; hsa-mir-566
Summary
This record was withdrawn by miRBase.
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Genomic context

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See MIR566 in Genome Data Viewer
Location:
3p21.31
Exon count:
1
Annotation release Status Assembly Chr Location
105 latest, but not current GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (50210759..50210852)
105 latest, but not current HuRef (GCF_000002125.1) 3 AC_000135.1 (50266468..50266561)
105 latest, but not current CHM1_1.1 (GCF_000306695.2) 3 NC_018914.2 (50163029..50163122)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000003.12 Chromosome 3 Reference GRCh38.p12 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. inhibition of miR566 expression increases the expression levels of VHL, decreases the expression levels of VEGF, and inhibits the invasive and migratory abilities of glioblastoma.
    Title: MicroRNA‑566 modulates vascular endothelial growth factor by targeting Von Hippel‑Landau in human glioblastoma in vitro and in vivo.
  2. this is the first report to demonstrate that miR-566 expression is significantly increased in glioma cells and modulated the EGFR pathway through direct targeting of VHL
    Title: MicroRNA-566 activates EGFR signaling and its inhibition sensitizes glioblastoma cells to nimotuzumab.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 (NOTE: not current)

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p12 Primary Assembly

    Range
    50173326..50173419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. NR_030291.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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