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P5CS delta l-pyrroline-5-carboxylate synthetase [ Phaeodactylum tricornutum CCAP 1055/1 ]

Gene ID: 7198171, updated on 21-Dec-2023

Summary

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Gene symbol
P5CS
Gene description
delta l-pyrroline-5-carboxylate synthetase
Locus tag
PHATRDRAFT_55086
Gene type
protein coding
RNA name
delta l-pyrroline-5-carboxylate synthetase
RefSeq status
PROVISIONAL
Organism
Phaeodactylum tricornutum CCAP 1055/1 (strain: CCAP 1055/1)
Lineage
Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae; Phaeodactylum
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Genomic context

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Location:
chromosome: 23
Exon count:
3
Sequence:
Chromosome: 23; NC_011691.1 (443526..446454, complement)

Chromosome 23 - NC_011691.1Genomic Context describing neighboring genes Neighboring gene predicted protein Neighboring gene predicted protein Neighboring gene predicted protein Neighboring gene predicted protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_011691.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Phaeodactylum genome reveals the evolutionary history of diatom genomes. Bowler C, et al. Nature, 2008 Nov 13. PMID 18923393

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glutamate 5-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glutamate-5-semialdehyde dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proline biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Names
delta l-pyrroline-5-carboxylate synthetase
XP_002184463.1
  • delta l-pyrroline-5-carboxylate synthetase contains a glutamate 5-kinase region followed by a gamma-glutamyl phosphate reductase region and catalyses the first and second steps in proline biosynthesis.Catalyses ATP + L-glutamate = ADP + L-glutamate 5-phosphate and L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_011691.1 Reference assembly

    Range
    443526..446454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002184427.1 → XP_002184463.1  delta l-pyrroline-5-carboxylate synthetase [Phaeodactylum tricornutum CCAP 1055/1]

    See identical proteins and their annotated locations for XP_002184463.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    B7GBH2
    Conserved Domains (3) summary
    cd07079
    Location:316 → 720
    ALDH_F18-19_ProA-GPR; Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19
    PLN02418
    Location:12 → 747
    PLN02418; delta-1-pyrroline-5-carboxylate synthase
    cl00452
    Location:28 → 306
    AAK; Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that ...
Nucleotide Protein
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