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HCL1 hydroxymethylglutaryl-coenzyme A lyase [ Phaeodactylum tricornutum CCAP 1055/1 ]

Gene ID: 7202194, updated on 11-Apr-2024

Summary

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Gene symbol
HCL1
Gene description
hydroxymethylglutaryl-coenzyme A lyase
Locus tag
PHATRDRAFT_13643
Gene type
protein coding
RNA name
hydroxymethylglutaryl-coenzyme A lyase
RefSeq status
PROVISIONAL
Organism
Phaeodactylum tricornutum CCAP 1055/1 (strain: CCAP 1055/1)
Lineage
Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae; Phaeodactylum
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Genomic context

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Location:
chromosome: 12
Exon count:
2
Sequence:
Chromosome: 12; NC_011680.1 (823057..824108)

Chromosome 12 - NC_011680.1Genomic Context describing neighboring genes Neighboring gene predicted protein Neighboring gene predicted protein Neighboring gene predicted protein Neighboring gene predicted protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_011680.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Phaeodactylum genome reveals the evolutionary history of diatom genomes. Bowler C, et al. Nature, 2008 Nov 13. PMID 18923393

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ketone body biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Names
hydroxymethylglutaryl-coenzyme A lyase
XP_002181269.1
  • Catalyses the transformation of 3-hydroxy-3-methylglutaryl-coenzyme A into acetyl-CoA and acetoacetate, with potential roles in ketogenesis (in lipid metabolism), leucine degradation, and mevalonate degradation.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_011680.1 Reference assembly

    Range
    823057..824108
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002181233.1 → XP_002181269.1  hydroxymethylglutaryl-coenzyme A lyase [Phaeodactylum tricornutum CCAP 1055/1]

    See identical proteins and their annotated locations for XP_002181269.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    B7G2V2
    Conserved Domains (2) summary
    PLN02746
    Location:1 → 320
    PLN02746; hydroxymethylglutaryl-CoA lyase
    pfam00682
    Location:12 → 296
    HMGL-like; HMGL-like
Nucleotide Protein
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