U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PHATRDRAFT_22113 bifunctional aspartokinase [ Phaeodactylum tricornutum CCAP 1055/1 ]

Gene ID: 7203242, updated on 21-Dec-2023

Summary

Go to the top of the page Help
Gene symbol
PHATRDRAFT_22113
Gene description
bifunctional aspartokinase
Locus tag
PHATRDRAFT_22113
Gene type
protein coding
RNA name
bifunctional aspartokinase
RefSeq status
PROVISIONAL
Organism
Phaeodactylum tricornutum CCAP 1055/1 (strain: CCAP 1055/1)
Lineage
Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae; Phaeodactylum
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 15
Exon count:
4
Sequence:
Chromosome: 15; NC_011683.1 (726456..729426)

Chromosome 15 - NC_011683.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_011683.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The Phaeodactylum genome reveals the evolutionary history of diatom genomes. Bowler C, et al. Nature, 2008 Nov 13. PMID 18923393

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables aspartate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables homoserine dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in aspartate family amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homoserine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Names
bifunctional aspartokinase
XP_002182284.1
  • Aspartate kinase () (AK) catalyzes the phosphorylation of aspartate. The product of this reaction can then be used in the biosynthesis of lysine or in the pathway leading to homoserine, which participates in the biosynthesis of threonine, isoleucine and methionine. Homoserine dehydrogenase () (HDh) catalyzes NAD-dependent reduction of aspartate beta-semialdehyde into homoserine. This reaction is the third step in a pathway leading from aspartate to homoserine. The latter participates in the biosynthesis of threonine and then isoleucine as well as in that of methioni; AK-HD 2; AK-HSDH 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_011683.1 Reference assembly

    Range
    726456..729426
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002182248.1 → XP_002182284.1  bifunctional aspartokinase, partial [Phaeodactylum tricornutum CCAP 1055/1]

    See identical proteins and their annotated locations for XP_002182284.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    B7G5P2
    Conserved Domains (5) summary
    cd04921
    Location:362 → 439
    ACT_AKi-HSDH-ThrA-like_1; ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH)
    PRK09436
    Location:30 → 868
    thrA; bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional
    pfam00742
    Location:676 → 868
    Homoserine_dh; Homoserine dehydrogenase
    cl00452
    Location:30 → 340
    AAK; Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that ...
    cl09141
    Location:443 → 506
    ACT; ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases