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Bpifa3 BPI fold containing family A, member 3 [ Mus musculus (house mouse) ]

Gene ID: 73388, updated on 5-Mar-2024

Summary

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Official Symbol
Bpifa3provided by MGI
Official Full Name
BPI fold containing family A, member 3provided by MGI
Primary source
MGI:MGI:1920638
See related
Ensembl:ENSMUSG00000027482 AllianceGenome:MGI:1920638
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Splunc3; 1700058C13Rik
Summary
Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Orthologous to human BPIFA3 (BPI fold containing family A member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 69.4) See more
Orthologs
human all
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Genomic context

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Location:
2 H1; 2 76.15 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (153972222..153980279)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (154130302..154138359)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene BPI fold containing family A, member 2 Neighboring gene Friend virus susceptibility protein 1-like Neighboring gene STARR-seq mESC enhancer starr_06110 Neighboring gene BPI fold containing family A, member 1 Neighboring gene BPI fold containing family A, member 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†. Lu Y, et al. Biol Reprod, 2019 Aug 1. PMID 31201419, Free PMC Article
  2. Phylogenetic and evolutionary analysis of the PLUNC gene family. Bingle CD, et al. Protein Sci, 2004 Feb. PMID 14739326, Free PMC Article
  3. Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. Bingle CD, et al. Biochem Soc Trans, 2011 Aug. PMID 21787333, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2)  1 citation

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
BPI fold-containing family A member 3
Names
Novel LBP / BPI / CETP family, N-terminal domain containing protein
short palate, lung and nasal epithelium carcinoma-associated protein 3 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291079.1 → NP_001278008.1  BPI fold-containing family A member 3 isoform b precursor

    See identical proteins and their annotated locations for NP_001278008.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in its 3' terminal exon, which results in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a.
    Source sequence(s)
    AK006829, AL732466
    Consensus CDS
    CCDS71163.1
    UniProtKB/Swiss-Prot
    Q9D9J8
    Related
    ENSMUSP00000105368.2, ENSMUST00000109746.8
    Conserved Domains (1) summary
    pfam01273
    Location:40 → 219
    LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

  2. NM_028528.3 → NP_082804.1  BPI fold-containing family A member 3 isoform a precursor

    See identical proteins and their annotated locations for NP_082804.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AK006829, AL732466
    Consensus CDS
    CCDS16924.1
    UniProtKB/TrEMBL
    Q80X83
    Related
    ENSMUSP00000028984.7, ENSMUST00000028984.13
    Conserved Domains (1) summary
    pfam01273
    Location:40 → 219
    LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    153972222..153980279
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500259.2 → XP_006500322.1  BPI fold-containing family A member 3 isoform X1

    Conserved Domains (1) summary
    pfam01273
    Location:14 → 190
    LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

  2. XM_030252118.1 → XP_030107978.1  BPI fold-containing family A member 3 isoform X2

    Conserved Domains (1) summary
    pfam01273
    Location:14 → 190
    LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

RNA

  1. XR_003953724.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D9J8.1 GenPept UniProtKB/Swiss-Prot:Q9D9J8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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