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ZNF148 zinc finger protein 148 [ Homo sapiens (human) ]

Gene ID: 7707, updated on 7-Apr-2024

Summary

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Official Symbol
ZNF148provided by HGNC
Official Full Name
zinc finger protein 148provided by HGNC
Primary source
HGNC:HGNC:12933
See related
Ensembl:ENSG00000163848 MIM:601897; AllianceGenome:HGNC:12933
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BERF-1; BFCOL1; GDACCF; ZBP-89; ZFP148; pHZ-52; HT-BETA
Summary
The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies. [provided by RefSeq, Feb 2017]
Expression
Ubiquitous expression in thyroid (RPKM 14.7), ovary (RPKM 6.1) and 25 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
3q21.2
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (125225669..125375354, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (127952391..128102007, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (124944513..125094198, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene solute carrier family 12 member 8 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20416 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124839347-124839853 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124839854-124840359 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20417 Neighboring gene RNA, U6 small nuclear 230, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20418 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:124860668-124861491 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14661 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124862005-124862958 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20421 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20422 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20423 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20424 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20425 Neighboring gene NANOG hESC enhancer GRCh37_chr3:124872987-124873488 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14662 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20426 Neighboring gene microRNA 5092 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20427 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124930713-124931312 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14664 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14665 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr3:124950809-124952008 Neighboring gene NANOG hESC enhancer GRCh37_chr3:125058886-125059484 Neighboring gene deoxyuridine triphosphatase pseudogene 1 Neighboring gene DNAJB6 pseudogene 7 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:125087248-125087748 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:125087749-125088249 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14666 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20428 Neighboring gene uncharacterized LOC105374080 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20429 Neighboring gene RNA, U6 small nuclear 232, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Loss of ZNF148 enhances insulin secretion in human pancreatic β cells. de Klerk E, et al. JCI Insight, 2023 Jun 8. PMID 37288664, Free PMC Article
  2. Regulation between two alternative splicing isoforms ZNF148(FL) and ZNF148(ΔN), and their roles in the apoptosis and invasion of colorectal cancer. Liu Y, et al. Pathol Res Pract, 2019 Feb. PMID 30463804
  3. Targeting ZBP-89 for the treatment of hepatocellular carcinoma. Wang N, et al. Expert Opin Ther Targets, 2018 Oct. PMID 30142986
  4. Transcription factor ZNF148 is a negative regulator of human muscle differentiation. Bakke J, et al. Sci Rep, 2017 Aug 15. PMID 28811660, Free PMC Article
  5. ZNF148 modulates TOP2A expression and cell proliferation via ceRNA regulatory mechanism in colorectal cancer. Gao XH, et al. Medicine (Baltimore), 2017 Jan. PMID 28072746, Free PMC Article

See all (119) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Further delineation of the rare GDACCF (global developmental delay, absent or hypoplastic corpus callosum, dysmorphic facies syndrome): genotype and phenotype of 22 patients with ZNF148 mutations.
    Title: Further delineation of the rare GDACCF (global developmental delay, absent or hypoplastic corpus callosum, dysmorphic facies syndrome): genotype and phenotype of 22 patients with ZNF148 mutations.
  2. Upregulation of the ZNF148/PTX3 axis promotes malignant transformation of dendritic cells in glioma stem-like cells microenvironment.
    Title: Upregulation of the ZNF148/PTX3 axis promotes malignant transformation of dendritic cells in glioma stem-like cells microenvironment.
  3. Loss of ZNF148 enhances insulin secretion in human pancreatic beta cells.
    Title: Loss of ZNF148 enhances insulin secretion in human pancreatic β cells.
  4. Identification of the MALAT1/miR-106a-5p/ZNF148 feedback loop in regulating HaCaT cell proliferation, migration and apoptosis.
    Title: Identification of the MALAT1/miR-106a-5p/ZNF148 feedback loop in regulating HaCaT cell proliferation, migration and apoptosis.
  5. Loss of microRNA-147 function alleviates synovial inflammation through ZNF148 in rheumatoid and experimental arthritis.
    Title: Loss of microRNA-147 function alleviates synovial inflammation through ZNF148 in rheumatoid and experimental arthritis.
  6. ZBP-89 negatively regulates self-renewal of liver cancer stem cells via suppression of Notch1 signaling pathway.
    Title: ZBP-89 negatively regulates self-renewal of liver cancer stem cells via suppression of Notch1 signaling pathway.
  7. Here, we show that succinate accumulation induced by SDHB loss of function increased the expression of zinc finger protein 148 (ZNF148, also named ZBP-89) in astrointestinal stromal tumor (GIST) cells. Meanwhile, ZNF148 is found to be phosphorylated by ERK at Ser306, and this phosphorylation results in ZNF148 binding to Forkhead box M1 (FOXM1)
    Title: Upregulation of ZNF148 in SDHB-deficient gastrointestinal stromal tumor potentiates Forkhead box M1-mediated transcription and promotes tumor cell invasion.
  8. ZNF148(FL) could increase proliferation, invasion, and migration of colorectal cancer cells, while ZNF148(DeltaN) showed opposite effect; the two splicing isoforms of ZNF148 may exert a mutual antagonistic effect to each other on the malignant biological activities.
    Title: Regulation between two alternative splicing isoforms ZNF148(FL) and ZNF148(ΔN), and their roles in the apoptosis and invasion of colorectal cancer.
  9. Downregulation of ZNF148 drives the formation of a muscle phenotype with rapid expression of myosin heavy chain, even in proliferative conditions. This phenotype was most likely mediated by the robust and swift upregulation of MYOD and MEF2C.
    Title: Transcription factor ZNF148 is a negative regulator of human muscle differentiation.
  10. ZBP-89 is a potential tumor suppressor in hepatocellular carcinoma (HCC) and it can inhibit the growth of HCC via multiple channels; higher expression of ZBP-89 may predict better survivals and lower recurrence of HCC patients
    Title: Targeting ZBP-89 for the treatment of hepatocellular carcinoma.
Submit: New GeneRIF Correction See all GeneRIFs (42)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies
MedGen: C4310644 OMIM: 617260 GeneReviews: Not available
not available

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

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Replication interactions

Interaction Pubs
Knockdown of zinc finger protein 148 (ZNF148) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 PubMed

Go to the HIV-1, Human Interaction Database

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • DKFZp686L18248

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular defense response TAS
Traceable Author Statement
more info
 PubMed 
involved_in gamete generation IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of gene expression IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II EXP
Inferred from Experiment
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in substantia nigra development HEP PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  

General protein information

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Preferred Names
zinc finger protein 148
Names
CACCC box-binding protein
CLL-associated antigen KW-10
transcription factor ZBP-89
zinc finger DNA-binding protein 89

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_052987.1 RefSeqGene

    Range
    5030..154686
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001348424.1 → NP_001335353.1  zinc finger protein 148 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1-11 all encode the same isoform (a).
    Source sequence(s)
    AC108688
    Consensus CDS
    CCDS3031.1
    UniProtKB/Swiss-Prot
    D3DN27, O00389, O43591, Q58EY5, Q6PJ98, Q9UQR1
    UniProtKB/TrEMBL
    Q8TDH4
    Conserved Domains (3) summary
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:171 → 193
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:214 → 238
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001348425.2 → NP_001335354.1  zinc finger protein 148 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-11 all encode the same isoform (a).
    Source sequence(s)
    AA481164, AC108688, BC050260, DA726996
    Consensus CDS
    CCDS3031.1
    UniProtKB/Swiss-Prot
    D3DN27, O00389, O43591, Q58EY5, Q6PJ98, Q9UQR1
    UniProtKB/TrEMBL
    Q8TDH4
    Related
    ENSP00000420448.1, ENST00000485866.5
    Conserved Domains (3) summary
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:171 → 193
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:214 → 238
    zf-H2C2_2; Zinc-finger double domain

  3. NM_001348426.2 → NP_001335355.1  zinc finger protein 148 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-11 all encode the same isoform (a).
    Source sequence(s)
    AA481164, AC108688, BM917104, BQ441085, N27696
    Consensus CDS
    CCDS3031.1
    UniProtKB/Swiss-Prot
    D3DN27, O00389, O43591, Q58EY5, Q6PJ98, Q9UQR1
    UniProtKB/TrEMBL
    Q8TDH4
    Conserved Domains (3) summary
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:171 → 193
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:214 → 238
    zf-H2C2_2; Zinc-finger double domain

  4. NM_001348427.2 → NP_001335356.1  zinc finger protein 148 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-11 all encode the same isoform (a).
    Source sequence(s)
    AA481164, AC108688, AU121036, BM917104, BP237604, DA225087
    Consensus CDS
    CCDS3031.1
    UniProtKB/Swiss-Prot
    D3DN27, O00389, O43591, Q58EY5, Q6PJ98, Q9UQR1
    UniProtKB/TrEMBL
    Q8TDH4
    Related
    ENSP00000420038.2, ENST00000471196.2
    Conserved Domains (3) summary
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:171 → 193
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:214 → 238
    zf-H2C2_2; Zinc-finger double domain

  5. NM_001348428.2 → NP_001335357.1  zinc finger protein 148 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-11 all encode the same isoform (a).
    Source sequence(s)
    AA481164, AC108688, AU121036, BM917104, BP237604, DA780458, DB145818
    Consensus CDS
    CCDS3031.1
    UniProtKB/Swiss-Prot
    D3DN27, O00389, O43591, Q58EY5, Q6PJ98, Q9UQR1
    UniProtKB/TrEMBL
    Q8TDH4
    Conserved Domains (3) summary
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:171 → 193
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:214 → 238
    zf-H2C2_2; Zinc-finger double domain

  6. NM_001348429.2 → NP_001335358.1  zinc finger protein 148 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-11 all encode the same isoform (a).
    Source sequence(s)
    AA481164, AC108688, BQ441085, BU178504
    Consensus CDS
    CCDS3031.1
    UniProtKB/Swiss-Prot
    D3DN27, O00389, O43591, Q58EY5, Q6PJ98, Q9UQR1
    UniProtKB/TrEMBL
    Q8TDH4
    Conserved Domains (3) summary
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:171 → 193
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:214 → 238
    zf-H2C2_2; Zinc-finger double domain

  7. NM_001348430.2 → NP_001335359.1  zinc finger protein 148 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1-11 all encode the same isoform (a).
    Source sequence(s)
    AA481164, AC108688, AF432210, BQ674550
    Consensus CDS
    CCDS3031.1
    UniProtKB/Swiss-Prot
    D3DN27, O00389, O43591, Q58EY5, Q6PJ98, Q9UQR1
    UniProtKB/TrEMBL
    Q8TDH4
    Related
    ENSP00000420335.1, ENST00000484491.5
    Conserved Domains (3) summary
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:171 → 193
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:214 → 238
    zf-H2C2_2; Zinc-finger double domain

  8. NM_001348431.2 → NP_001335360.1  zinc finger protein 148 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 1. Variants 1-11 all encode the same isoform (a).
    Source sequence(s)
    AA481164, AC108688, BQ441085, BU178504, CR980884
    Consensus CDS
    CCDS3031.1
    UniProtKB/Swiss-Prot
    D3DN27, O00389, O43591, Q58EY5, Q6PJ98, Q9UQR1
    UniProtKB/TrEMBL
    Q8TDH4
    Related
    ENSP00000419322.1, ENST00000492394.5
    Conserved Domains (3) summary
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:171 → 193
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:214 → 238
    zf-H2C2_2; Zinc-finger double domain

  9. NM_001348432.2 → NP_001335361.1  zinc finger protein 148 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 1. Variants 1-11 all encode the same isoform (a).
    Source sequence(s)
    AA481164, AC108688, BQ441085, BU178504, DA780458
    Consensus CDS
    CCDS3031.1
    UniProtKB/Swiss-Prot
    D3DN27, O00389, O43591, Q58EY5, Q6PJ98, Q9UQR1
    UniProtKB/TrEMBL
    Q8TDH4
    Related
    ENSP00000514760.1, ENST00000700044.1
    Conserved Domains (3) summary
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:171 → 193
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:214 → 238
    zf-H2C2_2; Zinc-finger double domain

  10. NM_001348433.2 → NP_001335362.1  zinc finger protein 148 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR compared to variant 1. Variants 1-11 all encode the same isoform (a).
    Source sequence(s)
    AA481164, AC108688, BP378362, BU178504, BU941780, CV571288
    Consensus CDS
    CCDS3031.1
    UniProtKB/Swiss-Prot
    D3DN27, O00389, O43591, Q58EY5, Q6PJ98, Q9UQR1
    UniProtKB/TrEMBL
    Q8TDH4
    Conserved Domains (3) summary
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:171 → 193
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:214 → 238
    zf-H2C2_2; Zinc-finger double domain

  11. NM_001348434.2 → NP_001335363.1  zinc finger protein 148 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AA481164, AC108688, AU121036, BM917104, DA492993
    UniProtKB/TrEMBL
    Q8TDH4
    Conserved Domains (3) summary
    sd00017
    Location:131 → 151
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:129 → 151
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:172 → 196
    zf-H2C2_2; Zinc-finger double domain

  12. NM_001348436.2 → NP_001335365.1  zinc finger protein 148 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13) differs in the 5' UTR, 3' UTR, and 3' coding sequence compared to variant 1. The resulting isoform (c) has a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    AC108688, BC050260, DA726996, GD148926
    Related
    ENST00000700212.1
    Conserved Domains (3) summary
    COG5048
    Location:166 → 231
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:185 → 210
    zf-H2C2_2; Zinc-finger double domain

  13. NM_021964.3 → NP_068799.2  zinc finger protein 148 isoform a

    See identical proteins and their annotated locations for NP_068799.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-11 all encode the same isoform (a).
    Source sequence(s)
    AC108688
    Consensus CDS
    CCDS3031.1
    UniProtKB/Swiss-Prot
    D3DN27, O00389, O43591, Q58EY5, Q6PJ98, Q9UQR1
    UniProtKB/TrEMBL
    Q8TDH4
    Related
    ENSP00000353863.4, ENST00000360647.9
    Conserved Domains (3) summary
    sd00017
    Location:173 → 193
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:171 → 193
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:214 → 238
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    125225669..125375354 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    127952391..128102007 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9UQR1.2 GenPept UniProtKB/Swiss-Prot:Q9UQR1

Gene LinkOut

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