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SECISBP2 SECIS binding protein 2 [ Homo sapiens (human) ]

Gene ID: 79048, updated on 13-Apr-2024

Summary

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Official Symbol
SECISBP2provided by HGNC
Official Full Name
SECIS binding protein 2provided by HGNC
Primary source
HGNC:HGNC:30972
See related
Ensembl:ENSG00000187742 MIM:607693; AllianceGenome:HGNC:30972
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SBP2; THMA1
Summary
The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
Expression
Ubiquitous expression in testis (RPKM 20.1), thyroid (RPKM 9.1) and 25 other tissues See more
Orthologs
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Genomic context

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See SECISBP2 in Genome Data Viewer
Location:
9q22.2
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (89318500..89367117)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (101482274..101530894)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (91933415..91974578)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376136 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:91896966-91897484 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20005 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20006 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28527 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28528 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28529 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20007 Neighboring gene microRNA 3153 Neighboring gene CDC28 protein kinase regulatory subunit 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:91978812-91979312 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:91979313-91979813 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28530 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20008 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28531 Neighboring gene semaphorin 4D Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_108523 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_108535 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92020317-92021138 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92021139-92021959 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28535 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:92026366-92026868 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:92026869-92027370 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:92027622-92028122 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:92028123-92028623 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28536 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28537 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92040313-92041172 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28538 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28539 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28540 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28541 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28542 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28543 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:92046837-92047618 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92049183-92049964 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92049965-92050746 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92050747-92051528 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92051529-92052310 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92054729-92055306 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:92057617-92058192 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_108605 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92061728-92062338 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92064045-92064893 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20009 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28545 Neighboring gene proliferation-associated 2G4 pseudogene 6 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92080560-92081256 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92081257-92081952 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92082322-92083285 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28546 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:92086209-92086710 Neighboring gene ubiquitin-conjugating enzyme E2 variant 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. SECISBP2 is a novel prognostic predictor that regulates selenoproteins in diffuse large B-cell lymphoma. Taguchi T, et al. Lab Invest, 2021 Feb. PMID 33077808
  2. Loss of selenocysteine insertion sequence binding protein 2 suppresses the proliferation, migration/invasion and hormone secretion of human trophoblast cells via the PI3K/Akt and ERK signaling pathway. Li M, et al. Placenta, 2017 Jul. PMID 28623977
  3. The SBP2 protein central to selenoprotein synthesis contacts the human ribosome at expansion segment 7L of the 28S rRNA. Kossinova O, et al. RNA, 2014 Jul. PMID 24850884, Free PMC Article
  4. Novel compound heterozygous mutations in the SBP2 gene: characteristic clinical manifestations and the implications of GH and triiodothyronine in longitudinal bone growth and maturation. Hamajima T, et al. Eur J Endocrinol, 2012 Apr. PMID 22247018
  5. Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. Schoenmakers E, et al. J Clin Invest, 2010 Dec. PMID 21084748, Free PMC Article

See all (63) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Human Genetic Disorders Resulting in Systemic Selenoprotein Deficiency.
    Title: Human Genetic Disorders Resulting in Systemic Selenoprotein Deficiency.
  2. SECISBP2 is a novel prognostic predictor that regulates selenoproteins in diffuse large B-cell lymphoma.
    Title: SECISBP2 is a novel prognostic predictor that regulates selenoproteins in diffuse large B-cell lymphoma.
  3. Selenium-sensitive miR-181a-5p to participate and regulate SBP2 at post-transcriptional level.
    Title: Selenium-sensitive miRNA-181a-5p targeting SBP2 regulates selenoproteins expression in cartilage.
  4. SECISBP2 expression in healthy human palatal mucosa is strongly negatively correlated with serum cotinine levels.
    Title: Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes.
  5. In osteoarthritis pro-inflammatory factors mediate miR-181a-5p expression, and then miR-181a-5p regulates the pivotal selenoproteins GPX1 and GPX4 through its target SBP2, resulting in alterations to the overall activity of GPXs, which are the most important oxidation resistance proteins in cartilage.
    Title: The hsa-miR-181a-5p reduces oxidation resistance by controlling SECISBP2 in osteoarthritis.
  6. functions as a vital factor in selenoprotein translation and regulates the pro-oxidant/antioxidant balance in trophoblasts
    Title: Loss of selenocysteine insertion sequence binding protein 2 suppresses the proliferation, migration/invasion and hormone secretion of human trophoblast cells via the PI3K/Akt and ERK signaling pathway.
  7. SBP2 interacts directly with four proteins of the SMN complex and the methylosome core proteins.
    Title: SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation.
  8. SBP2 makes direct contacts with a discrete region of the human 28S rRNA.
    Title: The SBP2 protein central to selenoprotein synthesis contacts the human ribosome at expansion segment 7L of the 28S rRNA.
  9. The patient showed typical symptoms of SBP2 deficiency, and novel compound heterozygous mutations were identified in SBP2 (p.M515fsX563/p.Q79X).
    Title: Novel compound heterozygous mutations in the SBP2 gene: characteristic clinical manifestations and the implications of GH and triiodothyronine in longitudinal bone growth and maturation.
  10. Selenocysteine insertion sequence (SECIS)-binding protein 2 alters conformational dynamics of residues involved in tRNA accommodation in 80 S ribosomes.
    Title: Selenocysteine insertion sequence (SECIS)-binding protein 2 alters conformational dynamics of residues involved in tRNA accommodation in 80 S ribosomes.
Submit: New GeneRIF Correction See all GeneRIFs (22)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Thyroid hormone metabolism, abnormal 1
MedGen: C5676891 OMIM: 609698 GeneReviews: Not available
Compare labs

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ45753, DKFZp686C09169

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding EXP
Inferred from Experiment
more info
 PubMed 
enables RNA binding HDA PubMed 
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA 3'-UTR binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ribonucleoprotein complex binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables selenocysteine insertion sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables selenocysteine insertion sequence binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in forebrain neuron development IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
  
involved_in selenocysteine incorporation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in selenocysteine incorporation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in striatum development IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
selenocysteine insertion sequence-binding protein 2
Names
Sec insertion sequence-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012177.2 RefSeqGene

    Range
    5002..46165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001282688.2 → NP_001269617.1  selenocysteine insertion sequence-binding protein 2 isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame acceptor splice site in the 5' coding region compared to variant 1. The encoded isoform (2) is 1 aa shorter than isoform 1.
    Source sequence(s)
    AF380995, AK302852, AL160054, BG572344, BX000356
    UniProtKB/TrEMBL
    B4DZC7
    Conserved Domains (1) summary
    pfam01248
    Location:656 → 756
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  2. NM_001282689.2 → NP_001269618.1  selenocysteine insertion sequence-binding protein 2 isoform 3

    See identical proteins and their annotated locations for NP_001269618.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame acceptor splice site in the 5' coding region, which results in translation initiation from an alternate start codon compared to variant 1. The encoded isoform (3) is shorter, with a distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AK290182, AL929575, BG572344, BP219148
    Consensus CDS
    CCDS65076.1
    UniProtKB/TrEMBL
    B4DR97
    Related
    ENSP00000364959.3, ENST00000339901.8
    Conserved Domains (1) summary
    pfam01248
    Location:584 → 684
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  3. NM_001282690.1 → NP_001269619.1  selenocysteine insertion sequence-binding protein 2 isoform 4

    See identical proteins and their annotated locations for NP_001269619.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) contains an alternate 5' terminal exon, which results in translation initiation from an in-frame downstream start codon compared to variant 1. The encoded isoform (4) has a shorter N-terminus compared to isoform 1
    Source sequence(s)
    AK299161, AL160054, AL929575, BG572344, BX000356
    Consensus CDS
    CCDS65077.1
    UniProtKB/TrEMBL
    B4DR97
    Related
    ENSP00000436650.2, ENST00000534113.6
    Conserved Domains (1) summary
    pfam01248
    Location:589 → 689
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  4. NM_001354696.2 → NP_001341625.1  selenocysteine insertion sequence-binding protein 2 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) uses an alternate in-frame acceptor splice site in the mid-coding region compared to variant 1. The encoded shorter isoform (5) lacks an internal protein segment compared to isoform 1.
    Source sequence(s)
    BC068466, BC099900, BG572344, BP219148
    UniProtKB/TrEMBL
    Q59H19
    Conserved Domains (1) summary
    pfam01248
    Location:618 → 718
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  5. NM_001354697.2 → NP_001341626.1  selenocysteine insertion sequence-binding protein 2 isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) uses an alternate in-frame acceptor splice site in the mid-coding region compared to variant 1. The encoded shorter isoform (6) lacks an internal protein segment compared to isoform 1.
    Source sequence(s)
    BC068466, BG572344, BP219148, KX533480
    UniProtKB/TrEMBL
    Q59H19
    Conserved Domains (1) summary
    pfam01248
    Location:619 → 719
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  6. NM_001354698.2 → NP_001341627.1  selenocysteine insertion sequence-binding protein 2 isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) uses an alternate in-frame acceptor splice site and lacks an in-frame exon in the mid-coding region compared to variant 1. The encoded shorter isoform (7) lacks two internal protein segments compared to isoform 1.
    Source sequence(s)
    BC099900, BG572344, BP219148, KX533480
    UniProtKB/TrEMBL
    Q59H19
    Conserved Domains (1) summary
    pfam01248
    Location:588 → 688
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  7. NM_001354702.2 → NP_001341631.1  selenocysteine insertion sequence-binding protein 2 isoform 8

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) uses an alternate acceptor splice site in the mid-coding region and initiates translation from an alternate start codon compared to variant 1. The encoded isoform (8) is shorter, with a distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AI127999, BC068466, BG572344, BP219148
    Conserved Domains (1) summary
    pfam01248
    Location:362 → 462
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  8. NM_024077.5 → NP_076982.3  selenocysteine insertion sequence-binding protein 2 isoform 1

    See identical proteins and their annotated locations for NP_076982.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longest isoform (1).
    Source sequence(s)
    BC068466, BG572344, BP219148
    Consensus CDS
    CCDS6683.1
    UniProtKB/Swiss-Prot
    F8W892, Q5HYY1, Q7L1Z0, Q8IYC0, Q96T21, Q9H0A1
    UniProtKB/TrEMBL
    B4DZC7
    Related
    ENSP00000364965.3, ENST00000375807.8
    Conserved Domains (1) summary
    pfam01248
    Location:657 → 757
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    89318500..89367117
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047423856.1 → XP_047279812.1  selenocysteine insertion sequence-binding protein 2 isoform X5

    UniProtKB/Swiss-Prot
    F8W892, Q5HYY1, Q7L1Z0, Q8IYC0, Q96T21, Q9H0A1

  2. XM_047423857.1 → XP_047279813.1  selenocysteine insertion sequence-binding protein 2 isoform X5

    UniProtKB/Swiss-Prot
    F8W892, Q5HYY1, Q7L1Z0, Q8IYC0, Q96T21, Q9H0A1

  3. XM_047423859.1 → XP_047279815.1  selenocysteine insertion sequence-binding protein 2 isoform X8

  4. XM_017015122.3 → XP_016870611.1  selenocysteine insertion sequence-binding protein 2 isoform X7

    UniProtKB/TrEMBL
    B4DZC7

  5. XM_024447666.2 → XP_024303434.1  selenocysteine insertion sequence-binding protein 2 isoform X9

    UniProtKB/TrEMBL
    A0A1S5UZH3, Q59H19
    Conserved Domains (1) summary
    pfam01248
    Location:589 → 689
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  6. XM_047423854.1 → XP_047279810.1  selenocysteine insertion sequence-binding protein 2 isoform X1

  7. XM_011519000.3 → XP_011517302.1  selenocysteine insertion sequence-binding protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011517302.1

    UniProtKB/TrEMBL
    B4DR97
    Conserved Domains (1) summary
    pfam01248
    Location:589 → 689
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  8. XM_047423855.1 → XP_047279811.1  selenocysteine insertion sequence-binding protein 2 isoform X3

  9. XM_011519001.2 → XP_011517303.1  selenocysteine insertion sequence-binding protein 2 isoform X2

    UniProtKB/TrEMBL
    B4DR97
    Conserved Domains (1) summary
    pfam01248
    Location:559 → 659
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  10. XM_011519002.2 → XP_011517304.1  selenocysteine insertion sequence-binding protein 2 isoform X3

    UniProtKB/TrEMBL
    B4DR97
    Conserved Domains (1) summary
    pfam01248
    Location:551 → 651
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  11. XM_047423858.1 → XP_047279814.1  selenocysteine insertion sequence-binding protein 2 isoform X6

  12. XM_011519003.2 → XP_011517305.1  selenocysteine insertion sequence-binding protein 2 isoform X4

    UniProtKB/TrEMBL
    B4DR97
    Conserved Domains (1) summary
    pfam01248
    Location:550 → 650
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  13. XM_047423860.1 → XP_047279816.1  selenocysteine insertion sequence-binding protein 2 isoform X10

  14. XM_024447667.2 → XP_024303435.1  selenocysteine insertion sequence-binding protein 2 isoform X11

    UniProtKB/TrEMBL
    B4DR97
    Conserved Domains (1) summary
    pfam01248
    Location:545 → 645
    Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

  15. XM_047423861.1 → XP_047279817.1  selenocysteine insertion sequence-binding protein 2 isoform X12

  16. XM_047423862.1 → XP_047279818.1  selenocysteine insertion sequence-binding protein 2 isoform X13

  17. XM_047423863.1 → XP_047279819.1  selenocysteine insertion sequence-binding protein 2 isoform X14

    UniProtKB/TrEMBL
    Q9H948

RNA

  1. XR_007061351.1 RNA Sequence

  2. XR_007061350.1 RNA Sequence

  3. XR_007061352.1 RNA Sequence

  4. XR_007061353.1 RNA Sequence

  5. XR_007061354.1 RNA Sequence

  6. XR_007061347.1 RNA Sequence

  7. XR_929840.2 RNA Sequence

  8. XR_007061346.1 RNA Sequence

  9. XR_007061345.1 RNA Sequence

  10. XR_007061348.1 RNA Sequence

  11. XR_007061349.1 RNA Sequence

  12. XR_007061355.1 RNA Sequence

  13. XR_007061356.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    101482274..101530894
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054363775.1 → XP_054219750.1  selenocysteine insertion sequence-binding protein 2 isoform X5

    UniProtKB/Swiss-Prot
    F8W892, Q5HYY1, Q7L1Z0, Q8IYC0, Q96T21, Q9H0A1

  2. XM_054363776.1 → XP_054219751.1  selenocysteine insertion sequence-binding protein 2 isoform X5

    UniProtKB/Swiss-Prot
    F8W892, Q5HYY1, Q7L1Z0, Q8IYC0, Q96T21, Q9H0A1

  3. XM_054363779.1 → XP_054219754.1  selenocysteine insertion sequence-binding protein 2 isoform X8

  4. XM_054363778.1 → XP_054219753.1  selenocysteine insertion sequence-binding protein 2 isoform X7

  5. XM_054363780.1 → XP_054219755.1  selenocysteine insertion sequence-binding protein 2 isoform X9

    UniProtKB/TrEMBL
    A0A1S5UZH3

  6. XM_054363770.1 → XP_054219745.1  selenocysteine insertion sequence-binding protein 2 isoform X1

  7. XM_054363769.1 → XP_054219744.1  selenocysteine insertion sequence-binding protein 2 isoform X1

  8. XM_054363773.1 → XP_054219748.1  selenocysteine insertion sequence-binding protein 2 isoform X3

  9. XM_054363771.1 → XP_054219746.1  selenocysteine insertion sequence-binding protein 2 isoform X2

  10. XM_054363772.1 → XP_054219747.1  selenocysteine insertion sequence-binding protein 2 isoform X3

  11. XM_054363777.1 → XP_054219752.1  selenocysteine insertion sequence-binding protein 2 isoform X6

  12. XM_054363774.1 → XP_054219749.1  selenocysteine insertion sequence-binding protein 2 isoform X4

  13. XM_054363781.1 → XP_054219756.1  selenocysteine insertion sequence-binding protein 2 isoform X10

  14. XM_054363782.1 → XP_054219757.1  selenocysteine insertion sequence-binding protein 2 isoform X11

  15. XM_054363783.1 → XP_054219758.1  selenocysteine insertion sequence-binding protein 2 isoform X12

  16. XM_054363784.1 → XP_054219759.1  selenocysteine insertion sequence-binding protein 2 isoform X13

  17. XM_054363785.1 → XP_054219760.1  selenocysteine insertion sequence-binding protein 2 isoform X14

    UniProtKB/TrEMBL
    Q9H948

RNA

  1. XR_008488072.1 RNA Sequence

  2. XR_008488071.1 RNA Sequence

  3. XR_008488073.1 RNA Sequence

  4. XR_008488074.1 RNA Sequence

  5. XR_008488075.1 RNA Sequence

  6. XR_008488068.1 RNA Sequence

  7. XR_008488065.1 RNA Sequence

  8. XR_008488067.1 RNA Sequence

  9. XR_008488066.1 RNA Sequence

  10. XR_008488069.1 RNA Sequence

  11. XR_008488070.1 RNA Sequence

  12. XR_008488076.1 RNA Sequence

  13. XR_008488077.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q96T21.2 GenPept UniProtKB/Swiss-Prot:Q96T21

Gene LinkOut

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