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CHD9 chromodomain helicase DNA binding protein 9 [ Homo sapiens (human) ]

Gene ID: 80205, updated on 7-Apr-2024

Summary

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Official Symbol
CHD9provided by HGNC
Official Full Name
chromodomain helicase DNA binding protein 9provided by HGNC
Primary source
HGNC:HGNC:25701
See related
Ensembl:ENSG00000177200 MIM:616936; AllianceGenome:HGNC:25701
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AD013; CHD-9; CReMM; KISH2; PRIC320
Summary
Predicted to enable ATP binding activity; ATP-dependent activity, acting on DNA; and DNA binding activity. Predicted to be involved in DNA duplex unwinding and chromatin organization. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thyroid (RPKM 7.0), ovary (RPKM 6.1) and 25 other tissues See more
Orthologs
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Genomic context

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See CHD9 in Genome Data Viewer
Location:
16q12.2
Exon count:
56
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (53054991..53327497)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (58852750..59125294)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (53088903..53361409)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene MTCH2 pseudogene 4 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:53078114-53078979 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:53089197-53089728 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10831 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:53094537-53094763 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10832 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10833 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10834 Neighboring gene CHD9 neighbor Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10835 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10836 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr16:53119716-53120520 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:53125251-53125936 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr16:53132870-53134069 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10840 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10841 Neighboring gene MPRA-validated peak2596 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7494 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7495 Neighboring gene Sharpr-MPRA regulatory region 10980 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr16:53241747-53242336 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr16:53242337-53242924 Neighboring gene thyroid hormone receptor interactor 13 pseudogene Neighboring gene thyroid hormone receptor interactor 13 pseudogene Neighboring gene small nucleolar RNA U13 Neighboring gene RNA, 5S ribosomal pseudogene 427

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Dynamic interactions of chromatin-related mesenchymal modulator, a chromodomain helicase-DNA-binding protein, with promoters in osteoprogenitors. Shur I, et al. Stem Cells, 2006 May. PMID 16705189
  2. Characterization and functional analysis of CReMM, a novel chromodomain helicase DNA-binding protein. Shur I, et al. J Mol Biol, 2005 Sep 23. PMID 16095617
  3. Gene expression regulation by the Chromodomain helicase DNA-binding protein 9 (CHD9) chromatin remodeler is dispensable for murine development. Alendar A, et al. PLoS One, 2020. PMID 32453735, Free PMC Article
  4. Expression and regulation of CReMM, a chromodomain helicase-DNA-binding (CHD), in marrow stroma derived osteoprogenitors. Marom R, et al. J Cell Physiol, 2006 Jun. PMID 16523501
  5. PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex. Surapureddi S, et al. Biochem Biophys Res Commun, 2006 May 5. PMID 16554032

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Gene expression regulation by the Chromodomain helicase DNA-binding protein 9 (CHD9) chromatin remodeler is dispensable for murine development.
    Title: Gene expression regulation by the Chromodomain helicase DNA-binding protein 9 (CHD9) chromatin remodeler is dispensable for murine development.
  2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
  3. CReMM is a chromodomain helicase-DNA-binding protein expressed by osteoprogenitors
    Title: Expression and regulation of CReMM, a chromodomain helicase-DNA-binding (CHD), in marrow stroma derived osteoprogenitors.
  4. Chromatin immunoprecipitation assay was applied to follow the dynamics of CReMM binding to A/T-rich regions on promoters of genes that play a role in osteoblast maturation.
    Title: Dynamic interactions of chromatin-related mesenchymal modulator, a chromodomain helicase-DNA-binding protein, with promoters in osteoprogenitors.
  5. The CHD9 (CReMM) protein is extensively phosphorylated, has DNA-dependent ATPase activity, and binds to A/T-rich DNA. It is also expressed in mesenchymal progenitors.
    Title: Characterization and functional analysis of CReMM, a novel chromodomain helicase DNA-binding protein.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables helicase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
chromodomain-helicase-DNA-binding protein 9
Names
ATP-dependent helicase CHD9
PPAR-alpha-interacting complex protein 320 kDa
PPAR{gamma}-interacting cofactor 320 kDa
chromatin remodeling factor CHROM1
chromatin-related mesenchymal modulator
ciprofibrate bound protein p240
kismet homolog 2
peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein
proteinx0008
NP_001295248.1
NP_001339056.1
NP_001339085.1
NP_001339086.1
NP_001339087.1
NP_001369282.1
NP_001369283.1
NP_001369284.1
NP_079410.4
XP_005256225.1
XP_006721344.1
XP_006721346.1
XP_011521649.1
XP_016879208.1
XP_016879209.1
XP_016879213.1
XP_024306227.1
XP_024306229.1
XP_047290643.1
XP_047290644.1
XP_047290645.1
XP_047290646.1
XP_047290647.1
XP_047290648.1
XP_047290649.1
XP_047290650.1
XP_047290651.1
XP_047290652.1
XP_047290653.1
XP_047290654.1
XP_047290655.1
XP_047290656.1
XP_047290657.1
XP_047290658.1
XP_047290659.1
XP_047290660.1
XP_047290661.1
XP_047290662.1
XP_047290663.1
XP_047290664.1
XP_047290665.1
XP_047290666.1
XP_054169978.1
XP_054169979.1
XP_054169980.1
XP_054169981.1
XP_054169982.1
XP_054169983.1
XP_054169984.1
XP_054169985.1
XP_054169986.1
XP_054169987.1
XP_054169988.1
XP_054169989.1
XP_054169990.1
XP_054169991.1
XP_054169992.1
XP_054169993.1
XP_054169994.1
XP_054169995.1
XP_054169996.1
XP_054169997.1
XP_054169998.1
XP_054169999.1
XP_054170000.1
XP_054170001.1
XP_054170002.1
XP_054170003.1
XP_054170004.1
XP_054170005.1
XP_054170006.1
XP_054170007.1
XP_054170008.1
XP_054170009.1
XP_054170010.1
XP_054170011.1
XP_054170012.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001308319.2 → NP_001295248.1  chromodomain-helicase-DNA-binding protein 9 isoform 1

    See identical proteins and their annotated locations for NP_001295248.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1 and 7 both encode the same isoform (1).
    Source sequence(s)
    AC007906, AC079416
    Consensus CDS
    CCDS76865.1
    UniProtKB/Swiss-Prot
    B2RTU2, B9ZVQ0, O15025, Q1WF12, Q3L8U1, Q6DTK9, Q9H9V7, Q9UHM2
    UniProtKB/TrEMBL
    B7ZML1
    Related
    ENSP00000396345.2, ENST00000447540.6
    Conserved Domains (6) summary
    smart00592
    Location:2556 → 2600
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:811 → 1480
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG5422
    Location:176 → 362
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
    COG5641
    Location:161 → 558
    GAT1; GATA Zn-finger-containing transcription factor [Transcription]
    cd18663
    Location:770 → 828
    CD2_tandem_CHD5-9_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 5-9, and similar proteins
    cd18668
    Location:686 → 750
    CD1_tandem_CHD5-9_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 5-9, and similar proteins

  2. NM_001352127.3 → NP_001339056.1  chromodomain-helicase-DNA-binding protein 9 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3), as well as variant 2, encodes isoform 2.
    Source sequence(s)
    AC007906, AC079416
    Consensus CDS
    CCDS45485.1
    UniProtKB/TrEMBL
    B7ZML1
    Related
    ENSP00000455307.1, ENST00000564845.5
    Conserved Domains (6) summary
    smart00592
    Location:2540 → 2584
    BRK; domain in transcription and CHROMO domain helicases
    COG5048
    Location:80 → 479
    COG5048; FOG: Zn-finger [General function prediction only]
    cd00024
    Location:692 → 752
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:773 → 827
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam15350
    Location:164 → 355
    ETAA1; Ewing's tumor-associated antigen 1 homolog
    cl26465
    Location:811 → 1480
    SNF2_N; SNF2 family N-terminal domain

  3. NM_001352156.3 → NP_001339085.1  chromodomain-helicase-DNA-binding protein 9 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC007906, AC079416
    Consensus CDS
    CCDS92161.1
    UniProtKB/TrEMBL
    B7ZML1, H3BTW3
    Related
    ENSP00000457355.2, ENST00000565803.2
    Conserved Domains (4) summary
    smart00592
    Location:2083 → 2127
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:218 → 278
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:299 → 353
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    cl26465
    Location:337 → 1006
    SNF2_N; SNF2 family N-terminal domain

  4. NM_001352157.3 → NP_001339086.1  chromodomain-helicase-DNA-binding protein 9 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC007906, AC079416
    UniProtKB/TrEMBL
    Q461N2
    Conserved Domains (4) summary
    smart00592
    Location:2067 → 2111
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:218 → 278
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:299 → 353
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    cl26465
    Location:337 → 1006
    SNF2_N; SNF2 family N-terminal domain

  5. NM_001352158.3 → NP_001339087.1  chromodomain-helicase-DNA-binding protein 9 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC007906, AC079416
    UniProtKB/TrEMBL
    Q461N2
    Conserved Domains (4) summary
    smart00592
    Location:2034 → 2078
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:185 → 245
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:266 → 320
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    cl26465
    Location:304 → 973
    SNF2_N; SNF2 family N-terminal domain

  6. NM_001382353.1 → NP_001369282.1  chromodomain-helicase-DNA-binding protein 9 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variant 1, encodes isoform 1.
    Source sequence(s)
    AC007906, AC079416
    Consensus CDS
    CCDS76865.1
    UniProtKB/Swiss-Prot
    B2RTU2, B9ZVQ0, O15025, Q1WF12, Q3L8U1, Q6DTK9, Q9H9V7, Q9UHM2
    UniProtKB/TrEMBL
    B7ZML1
    Related
    ENSP00000381522.3, ENST00000398510.7
    Conserved Domains (6) summary
    smart00592
    Location:2556 → 2600
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:811 → 1480
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG5422
    Location:176 → 362
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
    COG5641
    Location:161 → 558
    GAT1; GATA Zn-finger-containing transcription factor [Transcription]
    cd18663
    Location:770 → 828
    CD2_tandem_CHD5-9_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 5-9, and similar proteins
    cd18668
    Location:686 → 750
    CD1_tandem_CHD5-9_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 5-9, and similar proteins

  7. NM_001382354.1 → NP_001369283.1  chromodomain-helicase-DNA-binding protein 9 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC007906, AC079416
    UniProtKB/TrEMBL
    Q461N2
    Conserved Domains (5) summary
    smart00592
    Location:2050 → 2094
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:304 → 973
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd18663
    Location:263 → 321
    CD2_tandem_CHD5-9_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 5-9, and similar proteins
    cd18668
    Location:179 → 243
    CD1_tandem_CHD5-9_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 5-9, and similar proteins
    cd18061
    Location:353 → 574
    DEXHc_CHD9; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 9

  8. NM_001382355.1 → NP_001369284.1  chromodomain-helicase-DNA-binding protein 9 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC007906, AC079416
    UniProtKB/TrEMBL
    Q461N2
    Conserved Domains (5) summary
    smart00592
    Location:2049 → 2093
    BRK; domain in transcription and CHROMO domain helicases
    PLN03142
    Location:304 → 973
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd18663
    Location:263 → 321
    CD2_tandem_CHD5-9_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 5-9, and similar proteins
    cd18668
    Location:179 → 243
    CD1_tandem_CHD5-9_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 5-9, and similar proteins
    cd18061
    Location:353 → 574
    DEXHc_CHD9; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 9

  9. NM_025134.7 → NP_079410.4  chromodomain-helicase-DNA-binding protein 9 isoform 2

    See identical proteins and their annotated locations for NP_079410.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variant 3, encodes isoform 2.
    Source sequence(s)
    AC007906, AC079416
    Consensus CDS
    CCDS45485.1
    UniProtKB/TrEMBL
    B7ZML1
    Related
    ENSP00000457466.1, ENST00000566029.5
    Conserved Domains (6) summary
    smart00592
    Location:2540 → 2584
    BRK; domain in transcription and CHROMO domain helicases
    COG5048
    Location:80 → 479
    COG5048; FOG: Zn-finger [General function prediction only]
    cd00024
    Location:692 → 752
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:773 → 827
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam15350
    Location:164 → 355
    ETAA1; Ewing's tumor-associated antigen 1 homolog
    cl26465
    Location:811 → 1480
    SNF2_N; SNF2 family N-terminal domain

RNA

  1. NR_168108.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007906

  2. NR_168109.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007906

  3. NR_168111.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007906

  4. NR_168112.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007906

  5. NR_168114.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007906

  6. NR_168116.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007906

  7. NR_168117.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007906

  8. NR_168119.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007906

  9. NR_168120.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007906

  10. NR_168123.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007906

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    53054991..53327497
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047434707.1 → XP_047290663.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  2. XM_047434693.1 → XP_047290649.1  chromodomain-helicase-DNA-binding protein 9 isoform X2

    UniProtKB/Swiss-Prot
    B2RTU2, B9ZVQ0, O15025, Q1WF12, Q3L8U1, Q6DTK9, Q9H9V7, Q9UHM2

  3. XM_047434692.1 → XP_047290648.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  4. XM_017023719.2 → XP_016879208.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

    UniProtKB/TrEMBL
    B7ZML1
    Conserved Domains (6) summary
    smart00592
    Location:2557 → 2601
    BRK; domain in transcription and CHROMO domain helicases
    COG5048
    Location:80 → 479
    COG5048; FOG: Zn-finger [General function prediction only]
    cd00024
    Location:692 → 752
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:773 → 827
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam15350
    Location:164 → 355
    ETAA1; Ewing's tumor-associated antigen 1 homolog
    cl26465
    Location:811 → 1480
    SNF2_N; SNF2 family N-terminal domain

  5. XM_047434703.1 → XP_047290659.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  6. XM_017023720.2 → XP_016879209.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

    UniProtKB/TrEMBL
    B7ZML1
    Conserved Domains (6) summary
    smart00592
    Location:2557 → 2601
    BRK; domain in transcription and CHROMO domain helicases
    COG5048
    Location:80 → 479
    COG5048; FOG: Zn-finger [General function prediction only]
    cd00024
    Location:692 → 752
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:773 → 827
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam15350
    Location:164 → 355
    ETAA1; Ewing's tumor-associated antigen 1 homolog
    cl26465
    Location:811 → 1480
    SNF2_N; SNF2 family N-terminal domain

  7. XM_047434699.1 → XP_047290655.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  8. XM_024450459.2 → XP_024306227.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

    UniProtKB/TrEMBL
    B7ZML1
    Conserved Domains (6) summary
    smart00592
    Location:2557 → 2601
    BRK; domain in transcription and CHROMO domain helicases
    COG5048
    Location:80 → 479
    COG5048; FOG: Zn-finger [General function prediction only]
    cd00024
    Location:692 → 752
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:773 → 827
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam15350
    Location:164 → 355
    ETAA1; Ewing's tumor-associated antigen 1 homolog
    cl26465
    Location:811 → 1480
    SNF2_N; SNF2 family N-terminal domain

  9. XM_047434695.1 → XP_047290651.1  chromodomain-helicase-DNA-binding protein 9 isoform X3

  10. XM_047434700.1 → XP_047290656.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  11. XM_005256168.5 → XP_005256225.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

    See identical proteins and their annotated locations for XP_005256225.1

    UniProtKB/TrEMBL
    B7ZML1
    Conserved Domains (6) summary
    smart00592
    Location:2557 → 2601
    BRK; domain in transcription and CHROMO domain helicases
    COG5048
    Location:80 → 479
    COG5048; FOG: Zn-finger [General function prediction only]
    cd00024
    Location:692 → 752
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:773 → 827
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam15350
    Location:164 → 355
    ETAA1; Ewing's tumor-associated antigen 1 homolog
    cl26465
    Location:811 → 1480
    SNF2_N; SNF2 family N-terminal domain

  12. XM_047434694.1 → XP_047290650.1  chromodomain-helicase-DNA-binding protein 9 isoform X3

  13. XM_047434696.1 → XP_047290652.1  chromodomain-helicase-DNA-binding protein 9 isoform X4

  14. XM_047434697.1 → XP_047290653.1  chromodomain-helicase-DNA-binding protein 9 isoform X5

  15. XM_047434698.1 → XP_047290654.1  chromodomain-helicase-DNA-binding protein 9 isoform X6

  16. XM_047434702.1 → XP_047290658.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  17. XM_047434688.1 → XP_047290644.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  18. XM_047434706.1 → XP_047290662.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  19. XM_047434689.1 → XP_047290645.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  20. XM_047434690.1 → XP_047290646.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  21. XM_047434701.1 → XP_047290657.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  22. XM_006721283.4 → XP_006721346.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

    See identical proteins and their annotated locations for XP_006721346.1

    UniProtKB/TrEMBL
    B7ZML1
    Conserved Domains (6) summary
    smart00592
    Location:2557 → 2601
    BRK; domain in transcription and CHROMO domain helicases
    COG5048
    Location:80 → 479
    COG5048; FOG: Zn-finger [General function prediction only]
    cd00024
    Location:692 → 752
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:773 → 827
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam15350
    Location:164 → 355
    ETAA1; Ewing's tumor-associated antigen 1 homolog
    cl26465
    Location:811 → 1480
    SNF2_N; SNF2 family N-terminal domain

  23. XM_047434704.1 → XP_047290660.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  24. XM_047434687.1 → XP_047290643.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  25. XM_047434705.1 → XP_047290661.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  26. XM_011523347.3 → XP_011521649.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

    See identical proteins and their annotated locations for XP_011521649.1

    UniProtKB/TrEMBL
    B7ZML1
    Conserved Domains (6) summary
    smart00592
    Location:2557 → 2601
    BRK; domain in transcription and CHROMO domain helicases
    COG5048
    Location:80 → 479
    COG5048; FOG: Zn-finger [General function prediction only]
    cd00024
    Location:692 → 752
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:773 → 827
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam15350
    Location:164 → 355
    ETAA1; Ewing's tumor-associated antigen 1 homolog
    cl26465
    Location:811 → 1480
    SNF2_N; SNF2 family N-terminal domain

  27. XM_017023724.2 → XP_016879213.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

    UniProtKB/TrEMBL
    B7ZML1
    Conserved Domains (6) summary
    smart00592
    Location:2106 → 2150
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:241 → 301
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:428 → 577
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00176
    Location:412 → 699
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:731 → 845
    Helicase_C; Helicase conserved C-terminal domain
    pfam00385
    Location:323 → 376
    Chromo; Chromo (CHRromatin Organization MOdifier) domain

  28. XM_006721281.3 → XP_006721344.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

    See identical proteins and their annotated locations for XP_006721344.1

    UniProtKB/TrEMBL
    B7ZML1
    Conserved Domains (6) summary
    smart00592
    Location:2557 → 2601
    BRK; domain in transcription and CHROMO domain helicases
    COG5048
    Location:80 → 479
    COG5048; FOG: Zn-finger [General function prediction only]
    cd00024
    Location:692 → 752
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:773 → 827
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam15350
    Location:164 → 355
    ETAA1; Ewing's tumor-associated antigen 1 homolog
    cl26465
    Location:811 → 1480
    SNF2_N; SNF2 family N-terminal domain

  29. XM_047434691.1 → XP_047290647.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  30. XM_047434709.1 → XP_047290665.1  chromodomain-helicase-DNA-binding protein 9 isoform X9

  31. XM_047434710.1 → XP_047290666.1  chromodomain-helicase-DNA-binding protein 9 isoform X10

  32. XM_047434708.1 → XP_047290664.1  chromodomain-helicase-DNA-binding protein 9 isoform X8

  33. XM_024450461.2 → XP_024306229.1  chromodomain-helicase-DNA-binding protein 9 isoform X11

    UniProtKB/TrEMBL
    Q461N2
    Related
    ENST00000219084.10
    Conserved Domains (4) summary
    smart00592
    Location:1896 → 1940
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:31 → 91
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:112 → 166
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    cl26465
    Location:150 → 819
    SNF2_N; SNF2 family N-terminal domain

RNA

  1. XR_007064921.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    58852750..59125294
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054314033.1 → XP_054170008.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  2. XM_054314017.1 → XP_054169992.1  chromodomain-helicase-DNA-binding protein 9 isoform X2

  3. XM_054314016.1 → XP_054169991.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  4. XM_054314008.1 → XP_054169983.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  5. XM_054314029.1 → XP_054170004.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  6. XM_054314009.1 → XP_054169984.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  7. XM_054314024.1 → XP_054169999.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  8. XM_054314011.1 → XP_054169986.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  9. XM_054314019.1 → XP_054169994.1  chromodomain-helicase-DNA-binding protein 9 isoform X3

  10. XM_054314025.1 → XP_054170000.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  11. XM_054314003.1 → XP_054169978.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  12. XM_054314018.1 → XP_054169993.1  chromodomain-helicase-DNA-binding protein 9 isoform X3

  13. XM_054314020.1 → XP_054169995.1  chromodomain-helicase-DNA-binding protein 9 isoform X4

  14. XM_054314021.1 → XP_054169996.1  chromodomain-helicase-DNA-binding protein 9 isoform X5

  15. XM_054314022.1 → XP_054169997.1  chromodomain-helicase-DNA-binding protein 9 isoform X6

  16. XM_054314030.1 → XP_054170005.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  17. XM_054314007.1 → XP_054169982.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  18. XM_054314031.1 → XP_054170006.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  19. XM_054314010.1 → XP_054169985.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  20. XM_054314026.1 → XP_054170001.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  21. XM_054314006.1 → XP_054169981.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  22. XM_054314027.1 → XP_054170002.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  23. XM_054314005.1 → XP_054169980.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  24. XM_054314012.1 → XP_054169987.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  25. XM_054314014.1 → XP_054169989.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  26. XM_054314015.1 → XP_054169990.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  27. XM_054314032.1 → XP_054170007.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  28. XM_054314028.1 → XP_054170003.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  29. XM_054314013.1 → XP_054169988.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  30. XM_054314035.1 → XP_054170010.1  chromodomain-helicase-DNA-binding protein 9 isoform X9

  31. XM_054314036.1 → XP_054170011.1  chromodomain-helicase-DNA-binding protein 9 isoform X10

  32. XM_054314034.1 → XP_054170009.1  chromodomain-helicase-DNA-binding protein 9 isoform X8

  33. XM_054314023.1 → XP_054169998.1  chromodomain-helicase-DNA-binding protein 9 isoform X7

  34. XM_054314004.1 → XP_054169979.1  chromodomain-helicase-DNA-binding protein 9 isoform X1

  35. XM_054314037.1 → XP_054170012.1  chromodomain-helicase-DNA-binding protein 9 isoform X11

RNA

  1. XR_008484740.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_015287.1: Suppressed sequence

    Description
    NM_015287.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3L8U1.2 GenPept UniProtKB/Swiss-Prot:Q3L8U1

Gene LinkOut

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