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PF3D7_1252200 chitinase [ Plasmodium falciparum 3D7 ]

Gene ID: 811552, updated on 25-Jan-2024

Summary

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Gene symbol
PF3D7_1252200
Gene description
chitinase
Locus tag
PF3D7_1252200
Gene type
protein coding
RNA name
chitinase
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 12
Exon count:
1
Sequence:
Chromosome: 12; NC_037284.1 (2125435..2126571)

Chromosome 12 - NC_037284.1Genomic Context describing neighboring genes Neighboring gene tRNA-Gln Neighboring gene rhoptry neck protein 3 Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037284.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Disruption of Plasmodium falciparum chitinase markedly impairs parasite invasion of mosquito midgut. Tsai YL, et al. Infect Immun, 2001 Jun. PMID 11349075, Free PMC Article
  2. The chitinase PfCHT1 from the human malaria parasite Plasmodium falciparum lacks proenzyme and chitin-binding domains and displays unique substrate preferences. Vinetz JM, et al. Proc Natl Acad Sci U S A, 1999 Nov 23. PMID 10570198, Free PMC Article
  3. Characterisation of Plasmodium invasive organelles; an ookinete microneme proteome. Lal K, et al. Proteomics, 2009 Mar. PMID 19206106, Free PMC Article
  4. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables chitin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables chitinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within chitin catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within symbiont entry into host IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in microneme IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
chitinase
XP_001350904.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037284.1 Reference assembly

    Range
    2125435..2126571
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001350868.1 → XP_001350904.1  chitinase [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001350904.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q8I4R4, Q9U4I9
    UniProtKB/TrEMBL
    A0A024V4Z3, A0A024VPE2, A0A024W3K9, A0A024WL61, A0A024X3B6, A0A0L7KI22, A0A2I0BZ67, W4ICF5, W4J0G7, W7EX35, W7FRK8, W7J8Y9
    Conserved Domains (1) summary
    pfam00704
    Location:55 → 292
    Glyco_hydro_18; Glycosyl hydrolases family 18
Nucleotide Protein
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