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PF3D7_1454700 6-phosphogluconate dehydrogenase, decarboxylating [ Plasmodium falciparum 3D7 ]

Gene ID: 812102, updated on 16-Oct-2023

Summary

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Gene symbol
PF3D7_1454700
Gene description
6-phosphogluconate dehydrogenase, decarboxylating
Locus tag
PF3D7_1454700
Gene type
protein coding
RNA name
6-phosphogluconate dehydrogenase, decarboxylating
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 14
Exon count:
1
Sequence:
Chromosome: 14; NC_037283.1 (2241433..2242839)

Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene iron sulfur cluster assembly protein, putative Neighboring gene mitochondrial ribosomal protein S11 precursor, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene conserved protein, unknown function

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037283.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target. Haeussler K, et al. J Mol Biol, 2018 Oct 19. PMID 30098336
  2. Proteome mapping of Plasmodium: identification of the P. yoelii remodellome. Siau A, et al. Sci Rep, 2016 Aug 9. PMID 27503796, Free PMC Article
  3. Identification of Plasmodium falciparum nuclear proteins by mass spectrometry and proposed protein annotation. Briquet S, et al. PLoS One, 2018. PMID 30379851, Free PMC Article
  4. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Oehring SC, et al. Genome Biol, 2012 Nov 26. PMID 23181666, Free PMC Article
  5. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables phosphogluconate dehydrogenase (decarboxylating) activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within pentose-phosphate shunt IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to xenobiotic stimulus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol TAS
Traceable Author Statement
more info
 PubMed 
located_in intracellular anatomical structure ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
6-phosphogluconate dehydrogenase, decarboxylating
XP_001348694.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037283.1 Reference assembly

    Range
    2241433..2242839
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001348658.3 → XP_001348694.1  6-phosphogluconate dehydrogenase, decarboxylating [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001348694.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024UYT7, A0A024VZM0, A0A024WH43, A0A024X140, A0A0L1IFL4, A0A0L7K6H8, A0A0L7M897, Q8IKT2, W4I9K0, W4IW03, W7F3T4, W7FMI8, W7JG11, W7JNT3
    Conserved Domains (1) summary
    PTZ00142
    Location:1 → 468
    PTZ00142; 6-phosphogluconate dehydrogenase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
6FQX_A.1
6FQX_B.1
6FQX_C.1
6FQX_D.1
6FQX_E.1
6FQX_F.1
6FQX_G.1
6FQX_H.1
6FQY_A.1
6FQY_B.1
6FQZ_A.1
6FQZ_B.1

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