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PF3D7_1469600 acetyl-CoA carboxylase [ Plasmodium falciparum 3D7 ]

Gene ID: 812246, updated on 16-Oct-2023

Summary

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Gene symbol
PF3D7_1469600
Gene description
acetyl-CoA carboxylase
Locus tag
PF3D7_1469600
Gene type
protein coding
RNA name
acetyl-CoA carboxylase
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 14
Exon count:
3
Sequence:
Chromosome: 14; NC_037283.1 (2852150..2862568)

Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene nucleoside transporter 3, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene mediator of RNA polymerase II transcription subunit 6, putative Neighboring gene conserved Plasmodium protein, unknown function

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037283.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Apicoplast acetyl Co-A carboxylase of the human malaria parasite is not targeted by cyclohexanedione herbicides. Goodman CD, et al. Int J Parasitol, 2014 Apr. PMID 24583112
  2. Host biotin is required for liver stage development in malaria parasites. Dellibovi-Ragheb TA, et al. Proc Natl Acad Sci U S A, 2018 Mar 13. PMID 29483266, Free PMC Article
  3. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. Boucher MJ, et al. PLoS Biol, 2018 Sep. PMID 30212465, Free PMC Article
  4. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by GeneDB

Component Evidence Code Pubs
located_in apicoplast HDA PubMed 
located_in apicoplast IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
acetyl-CoA carboxylase
XP_001348838.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037283.1 Reference assembly

    Range
    2852150..2862568
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001348802.2 → XP_001348838.2  acetyl-CoA carboxylase [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001348838.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2I0C1V7, Q8IKE1, W4I806
    Conserved Domains (3) summary
    cd06850
    Location:1303 → 1368
    biotinyl_domain; The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, ...
    COG0439
    Location:500 → 1144
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    cl40687
    Location:2611 → 3278
    Carboxyl_trans; Carboxyl transferase domain
Nucleotide Protein
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