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PF3D7_0202700 octaprenyl pyrophosphate synthase [ Plasmodium falciparum 3D7 ]

Gene ID: 812623, updated on 17-May-2024

Summary

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Gene symbol
PF3D7_0202700
Gene description
octaprenyl pyrophosphate synthase
Primary source
PlasmoDB:PF3D7_0202700
Locus tag
PF3D7_0202700
Gene type
protein coding
RNA name
octaprenyl pyrophosphate synthase
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 2
Exon count:
1
Sequence:
Chromosome: 2; NC_037280.1 (135523..137139)

Chromosome 2 - NC_037280.1Genomic Context describing neighboring genes Neighboring gene early transcribed membrane protein 2 Neighboring gene nucleic acid binding protein, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene palmitoyltransferase DHHC12, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037280.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Critical role for isoprenoids in apicoplast biogenesis by malaria parasites. Okada M, et al. Elife, 2022 Mar 8. PMID 35257658, Free PMC Article
  2. Carotenoid biosynthesis in intraerythrocytic stages of Plasmodium falciparum. Tonhosolo R, et al. J Biol Chem, 2009 Apr 10. PMID 19203994, Free PMC Article
  3. Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum. Tonhosolo R, et al. Biochem J, 2005 Nov 15. PMID 15984931, Free PMC Article
  4. Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Science, 1998 Nov 6. PMID 9804551
  5. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The cloning and characterization of octaprenyl pyrophosphate synthase in P. falciparum is reported.
    Title: Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables prenyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within isoprenoid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within plastid organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in apicoplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
octaprenyl pyrophosphate synthase
XP_001349541.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037280.1 Reference assembly

    Range
    135523..137139
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001349505.1 → XP_001349541.1  octaprenyl pyrophosphate synthase [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001349541.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024VE06, A0A024WE93, A0A024WY20, A0A024XFB8, A0A0L7KIE0, O96130, W4IQG3, W4J7X3, W7FJA4, W7FWJ3, W7K0X7, W7K533
    Conserved Domains (1) summary
    cd00685
    Location:256 → 457
    Trans_IPPS_HT; Trans-Isoprenyl Diphosphate Synthases, head-to-tail
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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