U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PF3D7_0206700 adenylosuccinate lyase [ Plasmodium falciparum 3D7 ]

Gene ID: 812659, updated on 16-Oct-2023

Summary

Go to the top of the page Help
Gene symbol
PF3D7_0206700
Gene description
adenylosuccinate lyase
Locus tag
PF3D7_0206700
Gene type
protein coding
RNA name
adenylosuccinate lyase
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 2
Exon count:
1
Sequence:
Chromosome: 2; NC_037280.1 (271594..273009)

Chromosome 2 - NC_037280.1Genomic Context describing neighboring genes Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene DNA-directed RNA polymerase III subunit RPC10, putative Neighboring gene merozoite surface protein 2 Neighboring gene merozoite surface protein 5

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037280.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum. Bulusu V, et al. Biochim Biophys Acta, 2009 Apr. PMID 19111634
  2. A network-based approach reveals novel invasion and Maurer's clefts-related proteins in Plasmodium falciparum. Das D, et al. Mol Omics, 2019 Dec 2. PMID 31631203
  3. Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Science, 1998 Nov 6. PMID 9804551
  4. Identification of Plasmodium falciparum nuclear proteins by mass spectrometry and proposed protein annotation. Briquet S, et al. PLoS One, 2018. PMID 30379851, Free PMC Article
  5. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Oehring SC, et al. Genome Biol, 2012 Nov 26. PMID 23181666, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. detailed kinetic and catalytic mechanism of the recombinant His-tagged adenylosuccinate lyase from Plasmodium falciparum is presented
    Title: Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within purine nucleotide metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in Maurer's cleft RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in nucleus HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
adenylosuccinate lyase
XP_001349577.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037280.1 Reference assembly

    Range
    271594..273009
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001349541.1 → XP_001349577.1  adenylosuccinate lyase [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001349577.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024WEQ5, A0A024WX02, A0A024XET5, A0A0L1I5Y6, A0A0L7K7E9, A0A193PBN1, A0A193PCG6, A0A193PCH1, A0A193PD39, E1CD68, E1CD69, E1CDE8, E1CDI1, E1CDY9, O15918, Q7KWJ4, W4IPH4, W4J859, W7FLF5, W7G238, W7K251
    Conserved Domains (1) summary
    cd01598
    Location:25 → 452
    PurB; PurB_like adenylosuccinases (adenylosuccinate lyase, ASL)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials