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PF3D7_0922200 S-adenosylmethionine synthetase [ Plasmodium falciparum 3D7 ]

Gene ID: 813498, updated on 17-May-2024

Summary

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Gene symbol
PF3D7_0922200
Gene description
S-adenosylmethionine synthetase
Primary source
PlasmoDB:PF3D7_0922200
Locus tag
PF3D7_0922200
See related
VEuPathDB:PF3D7_0922200
Gene type
protein coding
RNA name
S-adenosylmethionine synthetase
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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See PF3D7_0922200 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
1
Sequence:
Chromosome: 9; NC_004330.2 (903362..904570)

Chromosome 9 - NC_004330.2Genomic Context describing neighboring genes Neighboring gene dynein intermediate chain, putative Neighboring gene ubiquitin-like protein, putative Neighboring gene conserved protein, unknown function Neighboring gene para-aminobenzoic acid synthetase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004330.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization and redox regulation of Plasmodium falciparum methionine adenosyltransferase. Pretzel J, et al. J Biochem, 2016 Dec. PMID 27466371
  2. Molecular characterization of Plasmodium falciparum S-adenosylmethionine synthetase. Chiang PK, et al. Biochem J, 1999 Dec 1. PMID 10567242, Free PMC Article
  3. Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13. Gnädig NF, et al. PLoS Pathog, 2020 Apr. PMID 32310999, Free PMC Article
  4. PlasmoSEP: Predicting surface-exposed proteins on the malaria parasite using semisupervised self-training and expert-annotated data. El-Manzalawy Y, et al. Proteomics, 2016 Dec. PMID 27714937, Free PMC Article
  5. Food vacuole proteome of the malarial parasite Plasmodium falciparum. Lamarque M, et al. Proteomics Clin Appl, 2008 Sep. PMID 21136929

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables methionine adenosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within S-adenosylmethionine biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within cell redox homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in Maurer's cleft RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in cell surface RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in extracellular vesicle HDA PubMed 
located_in food vacuole HDA PubMed 
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
S-adenosylmethionine synthetase
XP_001352093.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004330.2 Reference assembly

    Range
    903362..904570
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001352057.1 → XP_001352093.1  S-adenosylmethionine synthetase [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001352093.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024V6I4, A0A024W970, A0A024WSV1, A0A024X880, A0A0L7K949, Q7K6A4, Q9GN14, W4IJA2, W4J0N7, W7F2G9, W7FZK0, W7JD21, W7JXX0
    Conserved Domains (1) summary
    PTZ00104
    Location:1 → 400
    PTZ00104; S-adenosylmethionine synthase; Provisional
Nucleotide Protein
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