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PF3D7_1364900 ferrochelatase [ Plasmodium falciparum 3D7 ]

Gene ID: 813892, updated on 17-May-2024

Summary

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Gene symbol
PF3D7_1364900
Gene description
ferrochelatase
Primary source
PlasmoDB:PF3D7_1364900
Locus tag
PF3D7_1364900
Gene type
protein coding
RNA name
ferrochelatase
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 13
Exon count:
4
Sequence:
Chromosome: 13; NC_004331.3 (2606397..2608050, complement)

Chromosome 13 - NC_004331.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene DNA-directed RNA polymerases I, II, and III subunit RPABC1, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene ribosomal protein S17, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004331.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondrial localization of functional ferrochelatase from Plasmodium falciparum. Nagaraj VA, et al. Mol Biochem Parasitol, 2009 Nov. PMID 19523497
  2. The heme biosynthesis pathway is essential for Plasmodium falciparum development in mosquito stage but not in blood stages. Ke H, et al. J Biol Chem, 2014 Dec 12. PMID 25352601, Free PMC Article
  3. A Prioritized and Validated Resource of Mitochondrial Proteins in Plasmodium Identifies Unique Biology. van Esveld SL, et al. mSphere, 2021 Oct 27. PMID 34494883, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables ferrochelatase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within heme biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

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Preferred Names
ferrochelatase
XP_001350360.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004331.3 Reference assembly

    Range
    2606397..2608050 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001350324.2 → XP_001350360.2  ferrochelatase [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001350360.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024W160, A0A0L7KER5, A0A2I0BS50, Q8ID58, Q8IFR0, W4J1F9
    Conserved Domains (1) summary
    pfam00762
    Location:27 → 346
    Ferrochelatase
Nucleotide Protein
Heading Accession and Version

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