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PF3D7_1026900 biotin--protein ligase 1 [ Plasmodium falciparum 3D7 ]

Gene ID: 8445054, updated on 10-Sep-2023

Summary

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Gene symbol
PF3D7_1026900
Gene description
biotin--protein ligase 1
Locus tag
PF3D7_1026900
Gene type
protein coding
RNA name
biotin--protein ligase 1
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 10
Exon count:
1
Sequence:
Chromosome: 10; NC_037281.1 (1125283..1126167)

Chromosome 10 - NC_037281.1Genomic Context describing neighboring genes Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene 40S ribosomal protein S2 Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene U3 small nucleolar ribonucleoprotein protein MPP10, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037281.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Development of a conditional localization approach to control apicoplast protein trafficking in malaria parasites. Roberts AD, et al. Traffic, 2019 Aug. PMID 31094037, Free PMC Article
  2. Apicoplast acetyl Co-A carboxylase of the human malaria parasite is not targeted by cyclohexanedione herbicides. Goodman CD, et al. Int J Parasitol, 2014 Apr. PMID 24583112
  3. Host biotin is required for liver stage development in malaria parasites. Dellibovi-Ragheb TA, et al. Proc Natl Acad Sci U S A, 2018 Mar 13. PMID 29483266, Free PMC Article
  4. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Plasmodium falciparum acetyl-CoA carboxylase gene product is expressed in blood stage parasites and accumulates in the apicoplast.
    Title: Apicoplast acetyl Co-A carboxylase of the human malaria parasite is not targeted by cyclohexanedione herbicides.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables biotin-[acetyl-CoA-carboxylase] ligase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within biotin carboxyl carrier protein biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
biotin--protein ligase 1
XP_002585414.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037281.1 Reference assembly

    Range
    1125283..1126167
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002585368.1 → XP_002585414.1  biotin--protein ligase 1 [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_002585414.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024V5G2, A0A024VQL8, A0A024WP53, A0A024X7A1, A0A0L0CVM1, A0A0L1ICQ2, A0A0L7K9W0, A0A0L7M3B5, C6S3D7, W4IGA2, W4J246, W7FBB5, W7FUB2, W7K4J6
    Conserved Domains (1) summary
    PTZ00275
    Location:1 → 294
    PTZ00275; biotin-acetyl-CoA-carboxylase ligase; Provisional
Nucleotide Protein
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Gene LinkOut

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