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RBK1 putative ribokinase [ Saccharomyces cerevisiae S288C ]

Gene ID: 850402, updated on 13-Apr-2024

Summary

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Gene symbol
RBK1
Gene description
putative ribokinase
Primary source
SGD:S000000632
Locus tag
YCR036W
See related
AllianceGenome:SGD:S000000632
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable ribokinase activity. Predicted to be involved in D-ribose catabolic process. Located in cytoplasm and nucleus. Orthologous to human RBKS (ribokinase). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_001135.5 (193297..194298)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene fatty acid elongase ELO2 Neighboring gene exosome non-catalytic core subunit RRP43 Neighboring gene SPX domain-containing inorganic phosphate transporter Neighboring gene Ras family guanine nucleotide exchange factor BUD5 Neighboring gene homeodomain mating type protein alpha2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001135.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The ribokinases of Arabidopsis thaliana and Saccharomyces cerevisiae are required for ribose recycling from nucleotide catabolism, which in plants is not essential to survive prolonged dark stress. Schroeder RY, et al. New Phytol, 2018 Jan. PMID 28921561
  2. The complete sequence of the 8.2 kb segment left of MAT on chromosome III reveals five ORFs, including a gene for a yeast ribokinase. Thierry A, et al. Yeast, 1990 Nov-Dec. PMID 1964349
  3. Genetic pleiotropy in Saccharomyces cerevisiae quantified by high-resolution phenotypic profiling. Ericson E, et al. Mol Genet Genomics, 2006 Jun. PMID 16534619
  4. TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks. Shimada K, et al. Mol Cell, 2013 Sep 26. PMID 24035500
  5. The complete DNA sequence of yeast chromosome III. Oliver SG, et al. Nature, 1992 May 7. PMID 1574125

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ribokinase activity IEA
Inferred from Electronic Annotation
more info
  
enables ribokinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in D-ribose catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in D-ribose catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in D-ribose metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphate-containing compound metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative ribokinase
NP_009965.2
  • Ribokinase, phosphorylates ribose to ribose-5-phosphate; required for recycling ribose during nucleotide metabolism

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 Reference assembly

    Range
    193297..194298
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178750.1 → NP_009965.2  TPA: putative ribokinase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009965.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VR46, P25332
    UniProtKB/TrEMBL
    A0A8H4BUN9, B3LUA5, B5VEY0
    Conserved Domains (1) summary
    cd01174
    Location:2 → 324
    ribokinase; Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25332.2

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