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CDA2 chitin deacetylase CDA2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851017, updated on 25-Jan-2024

Summary

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Gene symbol
CDA2
Gene description
chitin deacetylase CDA2
Primary source
SGD:S000004299
Locus tag
YLR308W
See related
AllianceGenome:SGD:S000004299
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables chitin deacetylase activity. Involved in ascospore wall assembly. Predicted to be located in ascospore-type prospore. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (747937..748875)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene chitin deacetylase CDA1 Neighboring gene Dpa10p Neighboring gene Imh1p Neighboring gene Ras family guanine nucleotide exchange factor CDC25

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the Specific Mode of Action of a Chitin Deacetylase and Separation of the Partially Acetylated Chitosan Oligosaccharides. Zhu XY, et al. Mar Drugs, 2019 Jan 22. PMID 30678277, Free PMC Article
  2. Expression, purification, and characterization of a cobalt-activated chitin deacetylase (Cda2p) from Saccharomyces cerevisiae. Martinou A, et al. Protein Expr Purif, 2002 Feb. PMID 11812231
  3. Yeast ascospore wall assembly requires two chitin deacetylase isozymes. Christodoulidou A, et al. FEBS Lett, 1999 Oct 29. PMID 10544249
  4. Two sporulation-specific chitin deacetylase-encoding genes are required for the ascospore wall rigidity of Saccharomyces cerevisiae. Christodoulidou A, et al. J Biol Chem, 1996 Dec 6. PMID 8940152
  5. cda1+, encoding chitin deacetylase is required for proper spore formation in Schizosaccharomyces pombe. Matsuo Y, et al. FEBS Lett, 2005 May 9. PMID 15862318

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables chitin binding IEA
Inferred from Electronic Annotation
more info
  
enables chitin deacetylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chitin deacetylase activity IEA
Inferred from Electronic Annotation
more info
  
enables chitin deacetylase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables chitin deacetylase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ascospore wall assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ascospore wall assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in ascospore wall assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
  
involved_in chitin catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in fungal-type cell wall biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in polysaccharide catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in sporulation resulting in formation of a cellular spore IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in ascospore-type prospore IEA
Inferred from Electronic Annotation
more info
  
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
chitin deacetylase CDA2
NP_013411.1
  • Chitin deacetylase; together with Cda1p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    747937..748875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182196.1 → NP_013411.1  TPA: chitin deacetylase CDA2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013411.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VYV2, Q06703
    UniProtKB/TrEMBL
    B3RHI7, B5VNK8, G2WJD1, N1NZZ9
    Conserved Domains (1) summary
    cl15692
    Location:119 → 291
    CE4_SF; Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q06703.1

Gene LinkOut

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