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BAP3 amino acid transporter BAP3 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851616, updated on 25-Apr-2024

Summary

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Gene symbol
BAP3
Gene description
amino acid transporter BAP3
Primary source
SGD:S000002453
Locus tag
YDR046C
See related
AllianceGenome:SGD:S000002453
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
PAP1
Summary
Enables amino acid transmembrane transporter activity. Involved in amino acid transport and transmembrane transport. Located in endoplasmic reticulum and mitochondrion. Human ortholog(s) of this gene implicated in cystinuria; lysinuric protein intolerance; and retinitis pigmentosa 68. Orthologous to several human genes including SLC7A1 (solute carrier family 7 member 1); SLC7A14 (solute carrier family 7 member 14); and SLC7A2 (solute carrier family 7 member 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (548762..550576, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene coproporphyrinogen oxidase Neighboring gene DNA-directed RNA polymerase III core subunit RPC11 Neighboring gene uroporphyrinogen decarboxylase HEM12 Neighboring gene Vms1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and chromosomal organization of a gene encoding a putative amino-acid permease from Saccharomyces cerevisiae. Mai B, et al. Gene, 1994 May 27. PMID 8200527
  2. The permease homologue Ssy1p controls the expression of amino acid and peptide transporter genes in Saccharomyces cerevisiae. Didion T, et al. Mol Microbiol, 1998 Feb. PMID 9489675
  3. Stp1p, Stp2p and Abf1p are involved in regulation of expression of the amino acid transporter gene BAP3 of Saccharomyces cerevisiae. de Boer M, et al. Nucleic Acids Res, 2000 Feb 15. PMID 10648791, Free PMC Article
  4. Regulation of expression of the amino acid transporter gene BAP3 in Saccharomyces cerevisiae. De Boer M, et al. Mol Microbiol, 1998 Nov. PMID 9822825
  5. Activity of the yeast Tat2p tryptophan permease is sensitive to the anti-tumor agent 4-phenylbutyrate. Liu M, et al. Curr Genet, 2004 Nov. PMID 15490173

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables amino acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in amino acid transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in organic substance transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
amino acid transporter BAP3
NP_010331.3
  • Amino acid permease; involved in uptake of cysteine, leucine, isoleucine and valine; BAP3 has a paralog, BAP2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    548762..550576 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180354.3 → NP_010331.3  TPA: amino acid transporter BAP3 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010331.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VS34, P41815
    UniProtKB/TrEMBL
    A0A8H8UMW6, A6ZY13, B3LGM1, C7GTA3
    Conserved Domains (1) summary
    COG0833
    Location:40 → 603
    LysP; Amino acid permease [Amino acid transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P41815.2

Gene LinkOut

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