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MAL32 alpha-glucosidase MAL32 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852602, updated on 4-Jan-2025

Summary

Official Symbol
MAL32
Official Full Name
alpha-glucosidase MAL32
Primary source
SGD:S000000503
Locus tag
YBR299W
See related
AllianceGenome:SGD:S000000503; FungiDB:YBR299W; VEuPathDB:YBR299W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables alpha-1,4-glucosidase activity and glucan 1,4-alpha-maltotriohydrolase activity. Involved in maltose catabolic process and sucrose catabolic process. Located in plasma membrane. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to human SLC3A1 (solute carrier family 3 member 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See MAL32 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (805351..807105)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene maltose permease Neighboring gene uncharacterized protein Neighboring gene seripauperin PAU24 Neighboring gene Cos2p

Interactions

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables alpha-1,4-glucosidase activity  
enables alpha-1,4-glucosidase activity PubMed 
enables alpha-1,4-glucosidase activity  
enables alpha-amylase activity  
enables glucan 1,4-alpha-maltotriohydrolase activity  
enables glucan 1,4-alpha-maltotriohydrolase activity PubMed 
enables hydrolase activity, acting on glycosyl bonds  
enables oligo-1,6-glucosidase activity  
enables sucrose alpha-glucosidase activity  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process  
involved_in disaccharide catabolic process  
involved_in maltose catabolic process  
involved_in maltose catabolic process PubMed 
involved_in maltose metabolic process  
involved_in sucrose catabolic process  
involved_in sucrose catabolic process PubMed 
Component Evidence Code Pubs
located_in plasma membrane PubMed 

General protein information

Preferred Names
alpha-glucosidase MAL32
NP_009858.3
  • Maltase (alpha-D-glucosidase); inducible protein involved in maltose catabolism; encoded in the MAL3 complex locus; functional in genomic reference strain S288C; hydrolyzes the disaccharides maltose, turanose, maltotriose, and sucrose

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    805351..807105
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178647.3NP_009858.3  TPA: alpha-glucosidase MAL32 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009858.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQU5, P38158
    UniProtKB/TrEMBL
    A6ZLN9, A6ZUU5, B3LML3, B5VEP2, C7GT48, F8LG06, G2WF18, N1PAX0
    Conserved Domains (2) summary
    cd11333
    Location:15501
    AmyAc_SI_OligoGlu_DGase; Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins
    pfam16657
    Location:511583
    Malt_amylase_C; Maltogenic Amylase, C-terminal domain
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